Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   QHG38_RS05260 Genome accession   NZ_CP123979
Coordinates   1070896..1071525 (+) Length   209 a.a.
NCBI ID   WP_049394643.1    Uniprot ID   -
Organism   Staphylococcus haemolyticus strain SH1275     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1065896..1076525
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QHG38_RS05235 (QHG38_05235) - 1066597..1067454 (-) 858 WP_011275370.1 SDR family oxidoreductase -
  QHG38_RS05240 (QHG38_05240) - 1067526..1068538 (-) 1013 Protein_1027 HoxN/HupN/NixA family nickel/cobalt transporter -
  QHG38_RS05245 (QHG38_05245) - 1068751..1069137 (+) 387 WP_011275373.1 hypothetical protein -
  QHG38_RS05250 (QHG38_05250) liaF 1069162..1069863 (+) 702 WP_011275374.1 cell wall-active antibiotics response protein LiaF -
  QHG38_RS05255 (QHG38_05255) vraS 1069860..1070906 (+) 1047 WP_011275375.1 sensor histidine kinase Regulator
  QHG38_RS05260 (QHG38_05260) vraR 1070896..1071525 (+) 630 WP_049394643.1 two-component system response regulator VraR Regulator
  QHG38_RS05265 (QHG38_05265) - 1071589..1072800 (-) 1212 WP_011275377.1 YihY/virulence factor BrkB family protein -
  QHG38_RS05270 (QHG38_05270) - 1072997..1073281 (-) 285 WP_011275378.1 YtxH domain-containing protein -
  QHG38_RS05275 (QHG38_05275) - 1073287..1073751 (-) 465 WP_049394644.1 low molecular weight protein-tyrosine-phosphatase -
  QHG38_RS05280 (QHG38_05280) - 1073893..1074102 (+) 210 WP_011275380.1 DUF1128 domain-containing protein -
  QHG38_RS05285 (QHG38_05285) - 1074116..1075363 (+) 1248 WP_011275381.1 aminopeptidase -
  QHG38_RS05290 (QHG38_05290) - 1075396..1075929 (+) 534 WP_011275382.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23561.21 Da        Isoelectric Point: 5.0058

>NTDB_id=823530 QHG38_RS05260 WP_049394643.1 1070896..1071525(+) (vraR) [Staphylococcus haemolyticus strain SH1275]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEIVGEGESGKDAIAKAHELKPDLILMDLLMDDMDGVEATTQIKKDLPHVKVV
MLTSFIEDKEVYRALDAGVDSYILKTTSASDIADAVRKTFNGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=823530 QHG38_RS05260 WP_049394643.1 1070896..1071525(+) (vraR) [Staphylococcus haemolyticus strain SH1275]
ATGACGATTAAAGTTTTGTTCGTTGATGACCATGAAATGGTTCGAATTGGGATATCAAGTTATCTATCAACACAATCTGA
CATTGAGATAGTTGGAGAAGGGGAATCTGGTAAAGATGCCATTGCAAAAGCTCATGAATTAAAACCTGATTTAATTCTTA
TGGATTTATTAATGGATGATATGGATGGCGTTGAAGCAACTACTCAAATCAAAAAAGATTTGCCACATGTTAAAGTTGTA
ATGTTAACTAGTTTTATTGAAGATAAAGAGGTATATAGAGCATTAGATGCTGGTGTAGATAGCTATATTTTAAAAACGAC
TAGTGCTAGTGATATAGCCGACGCAGTACGCAAAACTTTTAATGGTGAATCCGTATTTGAACCAGAAGTTTTAGTTAAGA
TGCGTAACAGAATGAAGAAACGTGCAGAATTATATGAAATGCTGACTGAGCGTGAAATGGAAATTTTATTATTAATTGCA
AAAGGTTATTCAAATCAAGAAATAGCGAGTGCTTCTCATATTACAATTAAAACCGTTAAAACTCATGTAAGTAATATATT
GAGTAAATTAGAAGTACAAGATAGAACACAAGCCGTAATTTATGCATTCCAACATAATTTGATTCAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

95.215

100

0.952
  degU Bacillus subtilis subsp. subtilis str. 168

33.929

100

0.364