Detailed information NTG0823529

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: QHG38_RS05255
• Genome accession: NZ_CP123979
• Coordinates: 1069860..1070906 (+)
• Length: 348 a.a.
• NCBI ID: WP_011275375.1
• Uniprot ID: A0A2A1K920
• Organism: Staphylococcus haemolyticus strain SH1275
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1064860..1075906

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QHG38_RS05230 (QHG38_05230)	map	1065720..1066472 (+)	753	WP_011275369.1	type I methionyl aminopeptidase	-
QHG38_RS05235 (QHG38_05235)	-	1066597..1067454 (-)	858	WP_011275370.1	SDR family oxidoreductase	-
QHG38_RS05240 (QHG38_05240)	-	1067526..1068538 (-)	1013	Protein_1027	HoxN/HupN/NixA family nickel/cobalt transporter	-
QHG38_RS05245 (QHG38_05245)	-	1068751..1069137 (+)	387	WP_011275373.1	hypothetical protein	-
QHG38_RS05250 (QHG38_05250)	liaF	1069162..1069863 (+)	702	WP_011275374.1	cell wall-active antibiotics response protein LiaF	-
QHG38_RS05255 (QHG38_05255)	vraS	1069860..1070906 (+)	1047	WP_011275375.1	sensor histidine kinase	Regulator
QHG38_RS05260 (QHG38_05260)	vraR	1070896..1071525 (+)	630	WP_049394643.1	two-component system response regulator VraR	Regulator
QHG38_RS05265 (QHG38_05265)	-	1071589..1072800 (-)	1212	WP_011275377.1	YihY/virulence factor BrkB family protein	-
QHG38_RS05270 (QHG38_05270)	-	1072997..1073281 (-)	285	WP_011275378.1	YtxH domain-containing protein	-
QHG38_RS05275 (QHG38_05275)	-	1073287..1073751 (-)	465	WP_049394644.1	low molecular weight protein-tyrosine-phosphatase	-
QHG38_RS05280 (QHG38_05280)	-	1073893..1074102 (+)	210	WP_011275380.1	DUF1128 domain-containing protein	-
QHG38_RS05285 (QHG38_05285)	-	1074116..1075363 (+)	1248	WP_011275381.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40179.58 Da
• Isoelectric Point: 6.0550

>NTDB_id=823529 QHG38_RS05255 WP_011275375.1 1069860..1070906(+) (vraS) [Staphylococcus haemolyticus strain SH1275]
MNHYLRAIGSMLILVYSMLTAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLVIILLCIIVGSILAYKINQQNQWIKS
QIEHAIEGETVGINDQNIELYNETIDLYQTLVPLNQELHRLRMKTQNLTNENYNMNDVKVKKIIENERQRLARELHDSVS
QQLFAASMMLSAIKETKLEAPLDQQIPVLEKMVQESQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVIHDI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQQDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNREDDNNDD

Nucleotide

• Length: 1047 bp

>NTDB_id=823529 QHG38_RS05255 WP_011275375.1 1069860..1070906(+) (vraS) [Staphylococcus haemolyticus strain SH1275]
ATGAACCACTACTTAAGAGCTATCGGTTCAATGCTTATACTAGTTTATAGCATGTTAACCGCGTTCTTATTTATAGATAA
AGTATTTGTTAATATTATCTATTTCCAAGGTATGTTTTATACTCAAATTTTTGGGATACCTGTTTTTCTATTTTTAAATT
TAGTCATCATTTTACTTTGTATTATAGTAGGTTCAATTCTCGCATATAAAATTAATCAACAAAATCAGTGGATTAAGTCG
CAAATTGAGCATGCCATTGAAGGAGAAACAGTAGGTATCAATGATCAAAACATTGAGCTCTATAACGAAACCATAGATCT
TTATCAAACATTAGTTCCTCTAAATCAAGAGTTGCACCGTTTACGAATGAAAACGCAAAACTTAACTAATGAAAATTACA
ATATGAATGATGTCAAAGTTAAGAAAATCATTGAGAATGAACGACAGAGATTAGCTCGCGAGTTACATGACTCTGTAAGT
CAACAACTTTTTGCAGCAAGTATGATGTTATCTGCTATAAAAGAAACAAAATTAGAGGCACCGCTTGATCAACAAATACC
AGTTTTAGAGAAAATGGTTCAGGAATCTCAACTTGAAATGCGCGCATTATTACTTCATTTGAGACCTTTAGGACTAAAAG
ATAAATCACTAGGTGAAGGTATCAAAGATTTAGTTATTGATTTGCAAAAGAAAGTGCCTATGAAAGTCATACACGATATT
CAAGATTTCAAGGTTCCTAAAGGTATAGAAGATCATTTATTTAGAATTACACAAGAGGCTATATCAAATACGTTAAGACA
TTCTAATGGAACTAAAGTCACAGTGGAATTATTTAACCAACAAGATTATCTATTACTTCGAATTCAAGATAATGGTAAGG
GATTCAATGTTGACGAGAAATTAGAACAAAGTTATGGATTAAAAAATATGAGAGAACGCGCATTAGAAATTGGTGCGACA
TTCCATATTGTTTCGTTACCGGATTCTGGAACGAGAATAGAAGTTAAAGCACCATTAAATAGGGAGGATGATAATAATGA
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

3D structure

• AlphaFold DB: A0A2A1K920

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	91.643	99.713	0.914