Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   R6U80_RS11225 Genome accession   NZ_CP137623
Coordinates   2274516..2275181 (+) Length   221 a.a.
NCBI ID   WP_313791898.1    Uniprot ID   -
Organism   Lactococcus lactis strain NCK401     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2269516..2280181
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R6U80_RS11190 (R6U80_11190) - 2270659..2270988 (-) 330 WP_039116243.1 lactococcin 972 family bacteriocin -
  R6U80_RS11195 (R6U80_11195) - 2271323..2271559 (-) 237 WP_306659750.1 LytTR family transcriptional regulator DNA-binding domain-containing protein -
  R6U80_RS11200 (R6U80_11200) - 2271496..2272014 (-) 519 WP_235586152.1 hypothetical protein -
  R6U80_RS11205 (R6U80_11205) - 2272206..2272427 (+) 222 WP_010906270.1 YqgQ family protein -
  R6U80_RS11210 (R6U80_11210) - 2272461..2273432 (+) 972 WP_017865099.1 ROK family glucokinase -
  R6U80_RS11215 (R6U80_11215) - 2273435..2273821 (+) 387 WP_004254540.1 rhodanese-like domain-containing protein -
  R6U80_RS11220 (R6U80_11220) - 2273903..2274349 (-) 447 WP_058223018.1 DNA starvation/stationary phase protection protein -
  R6U80_RS11225 (R6U80_11225) cclA/cilC 2274516..2275181 (+) 666 WP_313791898.1 prepilin peptidase Machinery gene
  R6U80_RS11230 (R6U80_11230) dinB 2275132..2276226 (-) 1095 WP_023164600.1 DNA polymerase IV -
  R6U80_RS11235 (R6U80_11235) - 2276305..2276796 (-) 492 WP_010906273.1 prolyl-tRNA synthetase associated domain-containing protein -
  R6U80_RS11240 (R6U80_11240) - 2276875..2278368 (-) 1494 WP_015427125.1 basic amino acid/polyamine antiporter -
  R6U80_RS11245 (R6U80_11245) - 2278560..2279690 (-) 1131 WP_004254526.1 aminotransferase -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25664.87 Da        Isoelectric Point: 8.8481

>NTDB_id=822703 R6U80_RS11225 WP_313791898.1 2274516..2275181(+) (cclA/cilC) [Lactococcus lactis strain NCK401]
MDILFIFVIGSIFGSFFGLIVDRIPLRKSIIFGRSHCDSCQQLLAYRDLIPIFSQISSGSHCRYCKSKIPYLYVFLEFSS
ALIFILAWVNYLKPSQFLLIILSLILSAFDYRQHSFPFVIWFIFALSFILIFPLSPLFYFWLILAVLAEKFNLRVGSGDF
LWFFTASFSLTFLNEMLLLQIACSLGIIYYLITKKRVEIAFIPFLTIAYLMLLFGHQILSP

Nucleotide


Download         Length: 666 bp        

>NTDB_id=822703 R6U80_RS11225 WP_313791898.1 2274516..2275181(+) (cclA/cilC) [Lactococcus lactis strain NCK401]
ATGGACATTTTATTTATATTTGTAATTGGAAGTATTTTTGGTTCCTTTTTTGGCTTAATAGTTGACCGTATTCCCCTAAG
AAAATCAATTATTTTTGGACGCTCACATTGTGATTCTTGTCAGCAACTTTTAGCCTATCGTGATCTAATTCCTATTTTTT
CTCAAATAAGCTCTGGCTCACATTGCCGTTATTGTAAAAGTAAAATTCCATATTTATATGTTTTTTTGGAGTTCTCATCA
GCTTTAATTTTTATTTTAGCTTGGGTAAATTATCTTAAACCTAGTCAATTTTTACTGATTATTCTTTCACTAATTTTATC
TGCTTTTGATTATCGTCAGCACAGTTTTCCTTTTGTTATCTGGTTTATTTTTGCACTCAGTTTTATTTTAATATTTCCTC
TTTCTCCCCTTTTCTATTTTTGGCTTATTTTAGCCGTCTTAGCTGAAAAATTCAATTTAAGAGTTGGCAGCGGTGATTTT
TTATGGTTTTTTACCGCTTCATTTTCTCTAACTTTCTTAAACGAAATGCTGCTCCTTCAAATCGCTTGTTCACTTGGTAT
CATTTATTATCTAATCACAAAAAAACGAGTTGAAATTGCCTTCATCCCGTTTCTAACTATTGCATATCTAATGTTGCTTT
TTGGGCACCAAATTCTGTCACCGTAA

Domains

Predicted by InterProScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-90)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus mitis SK321

37.443

99.095

0.371
  cclA/cilC Streptococcus pneumoniae Rx1

37.674

97.285

0.367
  cclA/cilC Streptococcus pneumoniae D39

37.674

97.285

0.367
  cclA/cilC Streptococcus pneumoniae R6

37.674

97.285

0.367
  cclA/cilC Streptococcus pneumoniae TIGR4

37.209

97.285

0.362