Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   R6U80_RS09070 Genome accession   NZ_CP137623
Coordinates   1864359..1865726 (-) Length   455 a.a.
NCBI ID   WP_058221011.1    Uniprot ID   -
Organism   Lactococcus lactis strain NCK401     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1859359..1870726
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R6U80_RS09055 (R6U80_09055) - 1860530..1861963 (-) 1434 WP_017864852.1 6-phospho-beta-glucosidase -
  R6U80_RS09060 (R6U80_09060) yidD 1862086..1862352 (-) 267 WP_012898265.1 membrane protein insertion efficiency factor YidD -
  R6U80_RS09065 (R6U80_09065) - 1862469..1864211 (-) 1743 WP_098397274.1 1-deoxy-D-xylulose-5-phosphate synthase -
  R6U80_RS09070 (R6U80_09070) ciaH 1864359..1865726 (-) 1368 WP_058221011.1 cell wall metabolism sensor histidine kinase WalK Regulator
  R6U80_RS09075 (R6U80_09075) ciaR 1865819..1866487 (-) 669 WP_021722129.1 response regulator transcription factor Regulator
  R6U80_RS09080 (R6U80_09080) - 1866665..1867639 (-) 975 WP_058206283.1 LacI family DNA-binding transcriptional regulator -
  R6U80_RS09085 (R6U80_09085) - 1867792..1870047 (-) 2256 WP_012898269.1 glycoside hydrolase family 65 protein -

Sequence

Protein


Download         Length: 455 a.a.        Molecular weight: 51186.72 Da        Isoelectric Point: 9.4771

>NTDB_id=822681 R6U80_RS09070 WP_058221011.1 1864359..1865726(-) (ciaH) [Lactococcus lactis strain NCK401]
MKKIIKKVKSSAIVKNDGKNFLHFFLAFTVIFVALAVIIIQVMQLGMYRATDQNLHNLAQNRVFLEEAANNQLGTSSSQD
SGFGPNNSVIFYDSEGKNFMPSTGSNANISTNFGMSLLQKAMKFNEKHINTIQTVSVKNPYGDNLHYRYYTTSQFIITNS
DGTVTPVYMQIFSNVDQIQDAMSRAMWVIVTTMITFWLLSIIISLYLANWTLRPILAAYEKQKEFVENASHELRTPLAIL
QNRLELLFQKPTATIIDESENISESLSEVRNMRLLTSNLLNLARRDSGIRIEPEATTATYFENIFNSYEMLAENAGKKFS
GHLKLDGTINLDQALIKQLLTILFDNALKYTGDEGEISVDVQKNGGFLVFAVADNGEGISDEDKKKIFDRFFRVDKARTR
QKGGLGLGLSLAKQIVEAYNGKITVEDNKPKGTKFIVRIRVDSTISNPAKIFQKL

Nucleotide


Download         Length: 1368 bp        

>NTDB_id=822681 R6U80_RS09070 WP_058221011.1 1864359..1865726(-) (ciaH) [Lactococcus lactis strain NCK401]
TTGAAGAAAATAATTAAAAAAGTTAAATCTTCAGCTATTGTAAAAAATGATGGGAAAAATTTCCTTCATTTTTTTCTAGC
TTTTACAGTCATTTTTGTTGCTTTAGCCGTGATTATTATTCAAGTCATGCAATTAGGAATGTATCGAGCGACTGACCAAA
ATTTACACAATTTGGCTCAAAACCGAGTGTTTTTGGAAGAAGCAGCGAATAATCAATTAGGAACAAGTAGTTCACAAGAC
AGTGGCTTTGGACCTAATAATAGTGTAATTTTTTATGATTCAGAAGGAAAAAACTTTATGCCGTCAACTGGCTCAAATGC
AAATATAAGTACAAACTTTGGCATGAGTCTTTTGCAAAAAGCAATGAAATTTAATGAAAAACATATAAATACAATTCAGA
CAGTATCTGTAAAAAATCCTTATGGAGATAATTTGCACTATCGTTATTACACAACATCGCAATTTATCATTACAAATTCT
GATGGTACTGTGACGCCAGTTTATATGCAAATTTTTTCAAACGTTGACCAAATTCAAGATGCCATGAGTCGTGCCATGTG
GGTCATTGTGACAACAATGATTACTTTCTGGCTACTATCAATAATTATTAGTTTGTATCTTGCAAATTGGACATTAAGAC
CTATTCTGGCCGCTTATGAAAAACAAAAAGAATTTGTTGAAAATGCTTCACATGAATTGAGAACACCTCTGGCAATCTTG
CAAAATCGTCTAGAATTACTTTTCCAAAAGCCAACAGCAACAATTATTGATGAATCAGAAAATATTTCTGAAAGTTTATC
AGAAGTTCGTAATATGCGTTTATTAACAAGTAACTTACTGAACTTAGCTCGTCGAGATTCTGGAATCAGAATTGAGCCAG
AGGCGACTACGGCAACTTATTTTGAGAATATTTTTAATAGCTATGAAATGCTTGCTGAAAACGCAGGTAAAAAGTTTTCA
GGCCATTTGAAATTAGATGGAACGATTAATTTGGACCAAGCCCTGATTAAACAATTGCTAACCATCTTATTTGATAATGC
TCTTAAATACACGGGTGATGAGGGTGAAATCTCTGTAGATGTTCAAAAAAATGGGGGATTCTTAGTTTTTGCTGTCGCCG
ATAATGGTGAAGGAATTTCTGATGAAGATAAGAAAAAAATCTTTGACCGCTTTTTCCGAGTAGATAAAGCAAGAACGCGT
CAAAAAGGTGGCTTAGGTTTGGGTCTTTCTCTGGCCAAACAAATTGTTGAAGCTTACAATGGGAAGATTACAGTTGAAGA
TAATAAACCTAAAGGTACAAAATTCATTGTTAGAATTCGTGTGGATAGCACAATTTCAAATCCTGCAAAAATTTTCCAAA
AGTTGTAA

Domains

Predicted by InterProScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(222-288)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(332-441)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

48.372

94.505

0.457
  ciaH Streptococcus pneumoniae Rx1

44.444

98.901

0.44
  ciaH Streptococcus pneumoniae D39

44.444

98.901

0.44
  ciaH Streptococcus pneumoniae R6

44.444

98.901

0.44
  ciaH Streptococcus pneumoniae TIGR4

44.444

98.901

0.44