Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   R6U80_RS02500 Genome accession   NZ_CP137623
Coordinates   489360..491438 (+) Length   692 a.a.
NCBI ID   WP_023189444.1    Uniprot ID   -
Organism   Lactococcus lactis strain NCK401     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 484360..496438
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R6U80_RS02480 (R6U80_02480) - 486306..486776 (-) 471 WP_003130820.1 Rrf2 family transcriptional regulator -
  R6U80_RS02485 (R6U80_02485) gap 486949..487962 (+) 1014 WP_003130818.1 type I glyceraldehyde-3-phosphate dehydrogenase -
  R6U80_RS02490 (R6U80_02490) def 488105..488740 (-) 636 WP_003130816.1 peptide deformylase -
  R6U80_RS02495 (R6U80_02495) - 488888..489349 (+) 462 WP_308858979.1 RNA pyrophosphohydrolase -
  R6U80_RS02500 (R6U80_02500) uvrB 489360..491438 (+) 2079 WP_023189444.1 excinuclease ABC subunit UvrB Machinery gene
  R6U80_RS02505 (R6U80_02505) - 491634..492443 (+) 810 WP_081200248.1 ABC transporter substrate-binding protein -
  R6U80_RS02510 (R6U80_02510) - 492458..493576 (+) 1119 WP_058220806.1 M20 family metallopeptidase -
  R6U80_RS02515 (R6U80_02515) fabZ 493644..494099 (-) 456 WP_003130498.1 3-hydroxyacyl-ACP dehydratase FabZ -
  R6U80_RS02520 (R6U80_02520) fabI 494375..495127 (+) 753 WP_012897290.1 enoyl-ACP reductase FabI -

Sequence

Protein


Download         Length: 692 a.a.        Molecular weight: 79103.41 Da        Isoelectric Point: 4.5652

>NTDB_id=822650 R6U80_RS02500 WP_023189444.1 489360..491438(+) (uvrB) [Lactococcus lactis strain NCK401]
MAIERITDNKFELVSKYEPAGDQGEAIAELVDNIENGEKAQILRGATGTGKTYTMSQVIARTGKPTLVMAHNKTLAGQLY
SEFKEFFPNNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEY
QDSVVSLRPGQEISRDQLLNDLVGIQFERNDIDFQRGCFRVRGDVVEVFPASRDEHAFRVEFFGDEIDRIREIEVLTGQV
LGEVDHLAIFPATHFMTNDDRMEESIAKIEAELEEQLKVFRSEGKLLEAQRLEQRTNYDIEMLREMGYCNGVENYSRHMD
GREEGEPPYTLLDFFPDDFMIMIDESHMTMGQVKGMYNGDRARKEMLCNYGFRLPSALDNRPLKREEFESHVHQIVYVSA
TPGDYEMEQTDTIVEQIIRPTGLLDPVVEVRPMMGQIDDLVGEIHKRAEKNERVFVTTLTKKMSEDLTAYFKEMGIKVKY
MHSDIKTLERTEIIRDLRLGVFDVLVGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVILYSD
MAKALDENDPADKEILDSGYYTEYEGQKYKITRSMKHAMDETARRREIQMAYNEEHGITPQTIKKEIRDLIAITKKTDSG
EIEEVDASAMTKKERKALVKKLEKEMQQAASALDFEGAAQLRDMVLELRAMD

Nucleotide


Download         Length: 2079 bp        

>NTDB_id=822650 R6U80_RS02500 WP_023189444.1 489360..491438(+) (uvrB) [Lactococcus lactis strain NCK401]
ATGGCTATAGAAAGAATAACAGATAATAAATTTGAACTTGTTTCAAAATATGAGCCAGCCGGTGACCAAGGTGAGGCGAT
TGCTGAGTTAGTAGATAATATAGAGAATGGGGAAAAAGCTCAAATTTTACGTGGAGCAACAGGAACAGGGAAAACTTACA
CCATGAGTCAAGTGATTGCACGGACAGGTAAACCTACTCTTGTTATGGCCCATAATAAAACACTGGCTGGTCAATTATAC
AGTGAATTTAAAGAGTTTTTTCCAAATAATGCAGTCGAGTATTTCGTATCCTACTATGATTATTATCAACCCGAAGCCTA
TGTGCCAAGTTCTGACACCTATATTGAAAAAGACAGTTCGGTCAATGATGAAATTGATAAATTGCGTCATAGTGCGACCT
CAAGCTTATTGGAGCGTAATGATGTGATTGTTGTGGCCTCAGTTTCTTGTATTTATGGATTGGGTTCACCCAAAGAGTAT
CAAGATTCGGTGGTTTCATTGCGCCCAGGTCAAGAAATTTCTCGTGACCAACTTTTAAATGATTTGGTAGGAATTCAATT
TGAGCGAAATGATATTGACTTTCAACGGGGCTGTTTCCGAGTTCGCGGGGATGTTGTAGAAGTTTTTCCAGCCTCTCGTG
ATGAGCATGCCTTTCGTGTTGAATTTTTCGGTGATGAAATTGACCGTATCCGTGAAATTGAAGTTTTGACCGGACAAGTT
TTAGGTGAAGTAGACCATTTGGCAATTTTCCCAGCGACACATTTCATGACAAATGATGACCGTATGGAAGAATCAATTGC
CAAGATAGAAGCAGAATTAGAAGAACAATTAAAAGTTTTCCGCTCAGAAGGAAAACTTCTTGAGGCTCAACGCTTAGAAC
AAAGAACCAACTACGATATCGAAATGCTCCGTGAAATGGGTTATTGTAATGGGGTCGAAAACTATTCACGTCATATGGAT
GGGCGCGAGGAAGGCGAACCTCCGTATACTTTGCTTGATTTCTTTCCTGATGATTTCATGATTATGATTGATGAATCACA
CATGACAATGGGGCAAGTAAAAGGAATGTATAACGGTGACAGAGCCCGTAAAGAAATGCTTTGTAATTACGGATTCCGCC
TGCCTTCAGCGCTCGATAACCGTCCTTTAAAAAGAGAAGAATTTGAAAGTCATGTGCATCAAATTGTTTATGTTTCAGCA
ACCCCTGGGGATTATGAGATGGAGCAGACCGATACCATTGTTGAACAAATTATTCGTCCAACAGGTCTATTAGATCCTGT
CGTAGAAGTTCGACCAATGATGGGACAAATCGATGATTTAGTTGGTGAAATTCATAAACGAGCTGAGAAAAACGAACGAG
TATTCGTCACGACTTTGACTAAAAAGATGTCAGAAGATTTAACTGCCTATTTCAAGGAAATGGGGATAAAAGTTAAATAT
ATGCACTCGGATATCAAAACATTAGAACGAACCGAAATTATTCGGGATTTGCGTTTAGGAGTCTTTGATGTTCTGGTGGG
AATAAATCTGCTTCGCGAAGGGATTGACGTGCCAGAAGTTTCTTTAGTCGCGATTTTGGATGCTGATAAAGAAGGATTTT
TACGTAATGAGCGTGGCTTGATTCAGACCATTGGTCGTGCAGCACGTAATAGTGAAGGCCATGTTATTCTTTATTCTGAT
ATGGCTAAAGCCCTTGATGAAAATGATCCTGCGGATAAAGAAATCTTAGATAGTGGTTATTATACAGAATACGAGGGTCA
AAAGTATAAAATAACGCGTTCAATGAAACATGCGATGGATGAAACAGCCCGTCGACGTGAAATTCAAATGGCTTATAATG
AAGAACATGGAATCACACCTCAAACGATCAAAAAAGAAATTCGTGATTTGATTGCCATTACTAAGAAAACTGATTCTGGT
GAGATTGAAGAAGTCGATGCAAGTGCGATGACTAAGAAAGAACGTAAAGCATTAGTCAAAAAACTTGAAAAAGAAATGCA
ACAAGCGGCTAGCGCCCTCGACTTTGAAGGAGCTGCTCAGTTACGTGATATGGTATTAGAATTACGTGCAATGGATTGA

Domains

Predicted by InterProScan.

UvrB interaction domain (UvrB_inter)

(165-255)

Helicase conserved C-terminal domain (Helicase_C)

(441-550)

Type III restriction enzyme, res subunit (ResIII)

(19-144)

Ultra-violet resistance protein B (UvrB)

(590-628)

UvrB/uvrC motif (UVR)

(657-690)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

82.029

99.711

0.818
  uvrB Streptococcus pneumoniae D39

82.029

99.711

0.818
  uvrB Streptococcus pneumoniae TIGR4

81.884

99.711

0.816