Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   QFX60_RS07865 Genome accession   NZ_CP123748
Coordinates   1624652..1625338 (-) Length   228 a.a.
NCBI ID   WP_001792568.1    Uniprot ID   A0A133PXY3
Organism   Staphylococcus aureus strain 1.2     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1619652..1630338
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QFX60_RS07845 rpsT 1620566..1620817 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  QFX60_RS07850 holA 1620862..1621836 (-) 975 WP_304984666.1 DNA polymerase III subunit delta -
  QFX60_RS07855 comEC 1621893..1624094 (-) 2202 WP_001566051.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  QFX60_RS07860 - 1624099..1624560 (-) 462 WP_000439693.1 ComE operon protein 2 -
  QFX60_RS07865 comEA 1624652..1625338 (-) 687 WP_001792568.1 ComEA family DNA-binding protein Machinery gene
  QFX60_RS07870 - 1625378..1626094 (-) 717 WP_000084829.1 class I SAM-dependent methyltransferase -
  QFX60_RS07875 rsfS 1626097..1626450 (-) 354 WP_001088022.1 ribosome silencing factor -
  QFX60_RS07880 yqeK 1626451..1627035 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  QFX60_RS07885 nadD 1627025..1627594 (-) 570 WP_000725162.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  QFX60_RS07890 yhbY 1627597..1627887 (-) 291 WP_000955231.1 ribosome assembly RNA-binding protein YhbY -
  QFX60_RS07895 aroE 1627891..1628697 (-) 807 WP_000666761.1 shikimate dehydrogenase -
  QFX60_RS07900 yqeH 1628711..1629811 (-) 1101 WP_001280141.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25863.49 Da        Isoelectric Point: 9.3305

>NTDB_id=822383 QFX60_RS07865 WP_001792568.1 1624652..1625338(-) (comEA) [Staphylococcus aureus strain 1.2]
MVLLYQFLLRYKDFLTQWKLYILSAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHEKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=822383 QFX60_RS07865 WP_001792568.1 1624652..1625338(-) (comEA) [Staphylococcus aureus strain 1.2]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTCTAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGAAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTTGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A133PXY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

98.238

99.561

0.978
  comEA Staphylococcus aureus N315

97.357

99.561

0.969