Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   R6K63_RS11975 Genome accession   NZ_CP137556
Coordinates   2499464..2501440 (+) Length   658 a.a.
NCBI ID   WP_023435200.1    Uniprot ID   -
Organism   Pseudomonas aeruginosa strain CDC1270     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2494464..2506440
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R6K63_RS11960 - 2495542..2496708 (-) 1167 WP_223656181.1 glutathione-independent formaldehyde dehydrogenase -
  R6K63_RS11965 - 2497223..2498164 (-) 942 WP_054572497.1 LysR family transcriptional regulator -
  R6K63_RS11970 - 2498657..2499088 (+) 432 WP_029885976.1 DUF488 family protein -
  R6K63_RS11975 uvrB 2499464..2501440 (+) 1977 WP_023435200.1 excinuclease ABC subunit UvrB Machinery gene
  R6K63_RS11980 - 2501590..2502495 (-) 906 WP_023435201.1 LysR family transcriptional regulator -
  R6K63_RS11985 - 2502650..2503057 (+) 408 WP_023435202.1 ketosteroid isomerase-related protein -
  R6K63_RS11990 - 2503059..2503667 (+) 609 WP_023435203.1 GNAT family acetyltransferase -
  R6K63_RS11995 - 2503664..2504554 (+) 891 WP_006402492.1 carbon-nitrogen hydrolase family protein -
  R6K63_RS12000 frmR 2504837..2505112 (+) 276 WP_007182548.1 formaldehyde-responsive transcriptional repressor FrmR -
  R6K63_RS12005 - 2505172..2506281 (+) 1110 WP_023435204.1 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase -

Sequence

Protein


Download         Length: 658 a.a.        Molecular weight: 74248.36 Da        Isoelectric Point: 5.1657

>NTDB_id=822347 R6K63_RS11975 WP_023435200.1 2499464..2501440(+) (uvrB) [Pseudomonas aeruginosa strain CDC1270]
MSTGTFILHSSYTPAGDQPEAIARLLSDIEEGATHQTLKGITGSGKTFTMANVIHRLKRPTLILAPNKTLTAQLYGEMKH
FFPENAVEYFVSYYDYFQPEIYMPGTDRFIPKDSAINDHLERLRLSTTKSLIERRDVIVVASVSSIYGLGDPDAYRALQI
ALSPGVKINQRELIRRLALLQYDRTERTLKRATFRVQGDVIDIFPADSEHRAVRVELLDDSVASVQWLDPVTGKTLGAID
HYLVSPKTLFAPPTNKIDSASKKILADMEERVAELNRNNRLVEANRLYERITHDVEMMREVGYCSGMENYSCYFSDRDPA
SPPITLLDYLPKDGLLFVDESHVMVPQISAMYRGDQARKETLIDYGFRLPSSKNNRPLNFGEFEKVKPQTIFVSATPGDY
ELKVSKDRVVEQVIRPTGLLDPEVEVRKSDGYIDDLLAEISKCVKKKNRVLVTTLTKVSAEELTDFLTDHGIRARYMHSD
IKAEDRVEIINGLRAGEFDVLIGISLLREGLDIPEASLVAILDADRAGFLRSAQALIQMIGRVARNENGKAILYADVTTP
AMKQAIDETNRRRQLQIAFNEENGISPVSSVRKLAGEETSTEEPTVHTEAFCENLSDLCDQITAKEQQLLEFTDTGDEQR
VEDIRHQLDGLYRQFIYI

Nucleotide


Download         Length: 1977 bp        

>NTDB_id=822347 R6K63_RS11975 WP_023435200.1 2499464..2501440(+) (uvrB) [Pseudomonas aeruginosa strain CDC1270]
ATGTCAACCGGTACGTTCATTCTGCACTCCAGCTATACGCCGGCGGGGGACCAGCCAGAGGCGATAGCGCGCCTACTGTC
GGACATAGAAGAAGGTGCGACACACCAGACGCTGAAAGGTATCACCGGCTCAGGTAAGACCTTTACGATGGCGAATGTGA
TTCATCGTCTGAAGCGGCCCACATTGATCTTGGCTCCTAACAAGACGTTGACCGCGCAGCTTTATGGTGAAATGAAGCAC
TTCTTTCCCGAGAATGCTGTCGAGTACTTCGTTTCCTACTACGATTATTTTCAGCCCGAGATCTATATGCCGGGCACCGA
TCGTTTCATTCCAAAGGACTCGGCCATCAACGACCACCTTGAGCGCCTACGCCTGTCCACGACCAAATCCTTGATTGAGC
GCCGCGATGTGATCGTCGTCGCTTCGGTGTCTTCAATCTACGGCCTGGGTGACCCGGATGCGTACCGAGCGTTACAGATC
GCTCTGTCCCCTGGCGTCAAAATAAACCAGAGAGAGCTGATTCGTCGCTTGGCTCTGCTGCAATATGATCGCACTGAGCG
CACTCTCAAACGTGCAACGTTTCGGGTGCAAGGTGATGTGATCGATATCTTTCCTGCTGATTCCGAGCATAGGGCAGTTC
GGGTGGAACTGCTGGATGACTCTGTTGCGTCTGTTCAATGGCTAGACCCTGTTACAGGTAAAACGCTGGGGGCAATTGAC
CATTACTTGGTTTCGCCAAAGACGCTTTTTGCACCGCCCACGAATAAAATAGATTCCGCGTCCAAGAAGATACTCGCTGA
TATGGAAGAGCGGGTTGCCGAGCTTAACAGAAATAATCGCTTGGTCGAGGCAAACAGGCTGTACGAGCGGATCACGCATG
ACGTGGAGATGATGCGCGAGGTAGGCTATTGTTCGGGGATGGAGAATTATTCCTGCTACTTCAGCGACCGGGACCCGGCC
TCGCCTCCGATCACATTGCTGGATTACCTGCCGAAAGATGGGCTTCTGTTCGTCGATGAATCCCACGTCATGGTGCCACA
GATATCCGCAATGTACCGGGGGGATCAGGCGCGCAAGGAGACGTTGATAGATTACGGGTTCCGCTTGCCTTCGTCTAAGA
ACAATCGCCCGTTGAACTTTGGTGAATTCGAGAAGGTCAAGCCACAGACCATCTTCGTTTCCGCGACGCCGGGTGACTAC
GAGTTGAAGGTGTCGAAAGACAGGGTTGTCGAACAGGTTATCAGGCCGACGGGACTGCTTGATCCCGAGGTTGAGGTGCG
CAAATCGGATGGGTACATAGATGATCTGCTTGCTGAAATATCGAAGTGCGTGAAGAAGAAAAATCGCGTGCTCGTGACCA
CGCTGACGAAGGTCAGTGCAGAAGAGCTAACGGATTTCTTGACGGACCATGGGATTCGAGCGCGCTACATGCATTCGGAC
ATAAAAGCGGAGGATCGTGTTGAGATCATCAATGGCCTGCGCGCAGGAGAGTTCGATGTTTTGATTGGGATTAGCCTTTT
GCGCGAAGGGCTGGATATTCCCGAGGCATCATTGGTTGCTATTCTCGATGCGGATCGGGCAGGCTTCCTGCGGTCGGCCC
AGGCACTCATTCAGATGATAGGTCGAGTTGCTCGGAATGAAAACGGAAAGGCGATCTTGTACGCCGACGTGACGACTCCG
GCGATGAAACAGGCGATCGATGAGACAAATAGGCGCAGGCAGCTTCAAATTGCCTTTAACGAAGAAAATGGAATTTCTCC
GGTCTCCTCTGTGCGAAAACTAGCAGGAGAAGAGACGAGTACGGAGGAGCCCACAGTTCATACCGAGGCTTTTTGCGAGA
ATTTGTCCGACCTTTGCGACCAAATTACTGCCAAGGAGCAACAGTTGCTCGAATTTACTGATACTGGCGACGAGCAGCGC
GTGGAAGATATCCGTCATCAGTTGGATGGGTTGTACCGGCAATTTATTTATATCTAA

Domains

Predicted by InterProScan.

Ultra-violet resistance protein B (UvrB)

(553-593)

Type III restriction enzyme, res subunit (ResIII)

(17-103)

Helicase conserved C-terminal domain (Helicase_C)

(435-546)

UvrB interaction domain (UvrB_inter)

(160-250)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

52.981

89.21

0.473
  uvrB Streptococcus pneumoniae R6

52.981

89.21

0.473
  uvrB Streptococcus pneumoniae D39

52.981

89.21

0.473