Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   QFX48_RS07875 Genome accession   NZ_CP123746
Coordinates   1624579..1625265 (-) Length   228 a.a.
NCBI ID   WP_001792568.1    Uniprot ID   A0A133PXY3
Organism   Staphylococcus aureus strain 1.3     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1619579..1630265
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QFX48_RS07855 rpsT 1620493..1620744 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  QFX48_RS07860 holA 1620789..1621763 (-) 975 WP_304984666.1 DNA polymerase III subunit delta -
  QFX48_RS07865 comEC 1621820..1624021 (-) 2202 WP_001566051.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  QFX48_RS07870 - 1624026..1624487 (-) 462 WP_000439693.1 ComE operon protein 2 -
  QFX48_RS07875 comEA 1624579..1625265 (-) 687 WP_001792568.1 ComEA family DNA-binding protein Machinery gene
  QFX48_RS07880 - 1625305..1626021 (-) 717 WP_000084829.1 class I SAM-dependent methyltransferase -
  QFX48_RS07885 rsfS 1626024..1626377 (-) 354 WP_001088022.1 ribosome silencing factor -
  QFX48_RS07890 yqeK 1626378..1626962 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  QFX48_RS07895 nadD 1626952..1627521 (-) 570 WP_000725162.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  QFX48_RS07900 yhbY 1627524..1627814 (-) 291 WP_000955231.1 ribosome assembly RNA-binding protein YhbY -
  QFX48_RS07905 aroE 1627818..1628624 (-) 807 WP_000666761.1 shikimate dehydrogenase -
  QFX48_RS07910 yqeH 1628638..1629738 (-) 1101 WP_001280141.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25863.49 Da        Isoelectric Point: 9.3305

>NTDB_id=822303 QFX48_RS07875 WP_001792568.1 1624579..1625265(-) (comEA) [Staphylococcus aureus strain 1.3]
MVLLYQFLLRYKDFLTQWKLYILSAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHEKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=822303 QFX48_RS07875 WP_001792568.1 1624579..1625265(-) (comEA) [Staphylococcus aureus strain 1.3]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTCTAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGAAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTTGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A133PXY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

98.238

99.561

0.978
  comEA Staphylococcus aureus N315

97.357

99.561

0.969