Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   R5016_RS01925 Genome accession   NZ_CP137507
Coordinates   408364..410340 (+) Length   658 a.a.
NCBI ID   WP_023093409.1    Uniprot ID   A0A6N1X1N0
Organism   Pseudomonas aeruginosa strain HPA0698     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 403364..415340
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R5016_RS01910 (R5016_01910) - 404449..405615 (-) 1167 WP_020924942.1 glutathione-independent formaldehyde dehydrogenase -
  R5016_RS01915 (R5016_01915) - 406130..407071 (-) 942 WP_028698648.1 LysR family transcriptional regulator -
  R5016_RS01920 (R5016_01920) - 407557..407988 (+) 432 WP_023628836.1 DUF488 family protein -
  R5016_RS01925 (R5016_01925) uvrB 408364..410340 (+) 1977 WP_023093409.1 excinuclease ABC subunit UvrB Machinery gene
  R5016_RS01930 (R5016_01930) - 410491..411396 (-) 906 WP_023093410.1 LysR family transcriptional regulator -
  R5016_RS01935 (R5016_01935) - 411551..411958 (+) 408 WP_017514126.1 ketosteroid isomerase-related protein -
  R5016_RS01940 (R5016_01940) - 411960..412568 (+) 609 WP_023093411.1 GNAT family N-acetyltransferase -
  R5016_RS01945 (R5016_01945) - 412565..413455 (+) 891 WP_023093412.1 carbon-nitrogen hydrolase family protein -
  R5016_RS01950 (R5016_01950) frmR 413738..414013 (+) 276 WP_023093413.1 formaldehyde-responsive transcriptional repressor FrmR -
  R5016_RS01955 (R5016_01955) - 414073..415182 (+) 1110 WP_011871467.1 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase -

Sequence

Protein


Download         Length: 658 a.a.        Molecular weight: 74366.54 Da        Isoelectric Point: 5.1679

>NTDB_id=821533 R5016_RS01925 WP_023093409.1 408364..410340(+) (uvrB) [Pseudomonas aeruginosa strain HPA0698]
MSTGMFILHSNYTPAGDQPEAIARLLSDIEDGATHQTLKGITGSGKTFTMANVIHRLKRPTLILAPNKTLTAQLYGEMKH
FFPENAVEYFVSYYDYFQPEIYMPGTDRFIPKDSAINDHLERLRLSTTKSLIERRDVIVVASVSSIYGLGDPDAYRALQI
ALSPGVKLNQRELIRRLALLQYDRTERTLKRATFRVQGDVIDIFPADSEYRAVRVELLDDTVASVQWMDPVTGKTLGEID
HYLVSPKTLFAPPTNKIDSASKKILADMEERVAELNRNNRLVEANRLYERITHDVEMMREVGYCSGMENYSCYFSDRDAA
SPPITLLDYLPKDGLLFVDESHVMVPQISAMYRGDQARKDTLIDYGFRLPSSKNNRPLNFDEFEKVKPQTIFVSATPGDY
ELRVSKGRVVEQVIRPTGLLDPKVEVRKADGYIDDLLAEISKCVKRKNRVLVTTLTKVSAEELTDFLTDNGIRARYMHSD
IKAEDRVEIINGLRAGEFDVLIGISLLREGLDIPEASLVAILDADRAGFLRSAHALIQMIGRVARNENGKAILYADAVTP
AMKQAIDETNRRRQLQIAFNEENGISPASSVRKLAGEETNTEEPTVHSEAFCENLSDLCDQITAKEQQLLEFTDTGDEQR
VEDIRRQLDGLYRQFIYI

Nucleotide


Download         Length: 1977 bp        

>NTDB_id=821533 R5016_RS01925 WP_023093409.1 408364..410340(+) (uvrB) [Pseudomonas aeruginosa strain HPA0698]
ATGTCAACCGGTATGTTTATTCTGCACTCCAACTATACGCCGGCGGGGGACCAGCCAGAGGCGATAGCGCGCCTGCTGTC
GGACATAGAAGACGGTGCGACGCACCAGACGCTGAAAGGTATCACCGGCTCAGGTAAGACCTTCACCATGGCCAATGTGA
TTCATCGTCTGAAGCGGCCTACGTTGATCTTGGCTCCTAACAAGACGTTGACCGCGCAGCTTTATGGTGAAATGAAGCAC
TTCTTTCCTGAGAACGCGGTCGAGTACTTCGTTTCCTACTACGATTATTTTCAGCCCGAAATCTATATGCCGGGCACCGA
TCGTTTCATTCCAAAGGACTCGGCCATCAATGACCACCTTGAGCGCCTGCGCCTGTCCACGACCAAATCCTTGATTGAGC
GTCGTGACGTGATCGTCGTCGCTTCGGTGTCTTCAATCTACGGCCTGGGTGATCCAGATGCATACCGAGCGCTACAGATC
GCTCTGTCCCCTGGGGTCAAACTAAACCAGAGAGAGCTAATTCGTCGCTTGGCTTTGCTGCAATATGATCGCACGGAGCG
CACTCTCAAGCGTGCAACGTTCCGCGTCCAAGGTGATGTGATTGACATTTTCCCCGCTGATTCCGAGTACAGGGCGGTTC
GGGTGGAACTGTTGGATGACACTGTTGCGTCTGTCCAATGGATGGACCCTGTTACCGGCAAGACGTTGGGAGAGATAGAC
CATTATTTGGTTTCGCCAAAAACGCTTTTCGCACCGCCCACGAACAAAATAGATTCCGCGTCCAAAAAGATACTCGCTGA
TATGGAAGAGCGGGTTGCCGAGCTGAACAGGAATAATCGCTTGGTCGAGGCAAACAGGCTGTACGAGCGGATCACGCATG
ACGTGGAAATGATGCGCGAGGTCGGCTATTGCTCGGGGATGGAGAATTATTCCTGCTACTTCAGCGACCGAGACGCAGCT
TCTCCTCCGATCACGTTGCTGGATTATTTGCCGAAAGACGGGCTGCTGTTCGTCGATGAATCTCATGTCATGGTGCCACA
GATATCCGCAATGTACCGGGGGGATCAGGCGCGCAAGGACACGCTGATCGATTACGGGTTCCGTTTGCCTTCATCGAAGA
ACAACCGGCCATTGAACTTTGACGAGTTCGAGAAGGTCAAGCCTCAGACCATCTTTGTTTCCGCTACTCCGGGCGACTAC
GAGCTGAGGGTGTCGAAAGGCAGGGTTGTCGAACAGGTTATCAGGCCAACGGGACTGCTTGACCCCAAGGTTGAAGTGCG
GAAAGCGGATGGATACATAGATGACCTGCTTGCCGAAATATCGAAGTGCGTGAAGAGAAAGAATCGAGTGCTTGTGACTA
CGCTGACGAAGGTCAGTGCAGAAGAGCTAACGGATTTCTTGACGGACAACGGGATTCGAGCGCGCTACATGCATTCGGAC
ATAAAAGCGGAGGATCGTGTTGAGATCATCAATGGCCTGCGCGCAGGAGAGTTCGATGTTTTGATTGGGATTAGTCTTTT
GCGCGAAGGGCTGGATATTCCAGAGGCATCATTGGTTGCCATTCTCGATGCAGACCGTGCAGGGTTCTTGCGTTCGGCCC
ATGCGCTCATTCAGATGATCGGTCGAGTCGCTCGGAATGAAAACGGCAAGGCGATCTTGTACGCCGACGCGGTGACGCCG
GCGATGAAGCAGGCGATCGATGAGACCAATAGGCGCAGGCAGCTTCAAATTGCCTTTAACGAGGAAAATGGGATTTCTCC
AGCCTCGTCTGTGCGAAAACTAGCAGGGGAAGAGACGAATACGGAGGAGCCCACCGTTCATTCCGAGGCTTTCTGCGAGA
ACTTGTCCGACCTTTGCGATCAGATCACTGCCAAGGAACAGCAGCTACTCGAATTTACCGATACCGGTGACGAGCAGCGC
GTCGAAGACATTCGTCGTCAGTTGGATGGGTTGTACCGGCAATTCATTTACATCTAA

Domains

Predicted by InterProScan.

Type III restriction enzyme, res subunit (ResIII)

(17-100)

UvrB interaction domain (UvrB_inter)

(160-250)

Helicase conserved C-terminal domain (Helicase_C)

(435-546)

Ultra-violet resistance protein B (UvrB)

(553-593)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6N1X1N0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

52.462

89.514

0.47
  uvrB Streptococcus pneumoniae R6

52.462

89.514

0.47
  uvrB Streptococcus pneumoniae D39

52.462

89.514

0.47