Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   R4701_RS06675 Genome accession   NZ_CP137114
Coordinates   1310763..1311662 (+) Length   299 a.a.
NCBI ID   WP_000904858.1    Uniprot ID   A0A0H2URY1
Organism   Streptococcus pneumoniae strain 15P3054     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1305763..1316662
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4701_RS06645 - 1305933..1306227 (+) 295 Protein_1284 hypothetical protein -
  R4701_RS06650 - 1306383..1307597 (+) 1215 WP_000666469.1 pyridoxal phosphate-dependent aminotransferase -
  R4701_RS06655 rpmH 1307742..1307876 (+) 135 WP_000831905.1 50S ribosomal protein L34 -
  R4701_RS06660 - 1308082..1309053 (+) 972 Protein_1287 DUF1542 domain-containing protein -
  R4701_RS06665 - 1309358..1310131 (+) 774 WP_000575642.1 TatD family hydrolase -
  R4701_RS06670 rnmV 1310131..1310691 (+) 561 WP_317805802.1 ribonuclease M5 -
  R4701_RS06675 comR 1310763..1311662 (+) 900 WP_000904858.1 helix-turn-helix transcriptional regulator Regulator
  R4701_RS06680 - 1311931..1313961 (+) 2031 WP_000825248.1 bacteriocin-associated integral membrane family protein -
  R4701_RS06685 - 1313963..1314604 (+) 642 WP_000565533.1 ABC transporter ATP-binding protein -
  R4701_RS06690 - 1314597..1314905 (+) 309 Protein_1293 hypothetical protein -
  R4701_RS06695 rsmA 1315036..1315908 (+) 873 WP_001216856.1 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35409.11 Da        Isoelectric Point: 4.7119

>NTDB_id=820132 R4701_RS06675 WP_000904858.1 1310763..1311662(+) (comR) [Streptococcus pneumoniae strain 15P3054]
MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPSLPKLDYIARRLGVPVYSLMPDFSALPSAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAQLIGDEFLVKKLTEEWQEDVKKYL

Nucleotide


Download         Length: 900 bp        

>NTDB_id=820132 R4701_RS06675 WP_000904858.1 1310763..1311662(+) (comR) [Streptococcus pneumoniae strain 15P3054]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGA
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGACTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTTCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGCCTCAGATTATAGAAAAAGAAGCTTATTCAATAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTCTT
TCTTTTGGAACAGAAGAAGGTAACTCAAATAGAGAATTACTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGAAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGCAGCTAATTGGAGATGAATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(70-291)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2URY1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus mutans UA159

37.755

98.328

0.371
  comR Streptococcus suis P1/7

37.457

97.324

0.365
  comR Streptococcus suis 05ZYH33

37.457

97.324

0.365
  comR Streptococcus pyogenes MGAS8232

36.242

99.666

0.361