Detailed information    

insolico Bioinformatically predicted

Overview

Name   brsR   Type   Regulator
Locus tag   R4712_RS04380 Genome accession   NZ_CP137110
Coordinates   875377..875817 (+) Length   146 a.a.
NCBI ID   WP_000861956.1    Uniprot ID   A0A0H2UNA2
Organism   Streptococcus pneumoniae strain 16H2041     
Function   antagonizing the proteolysis of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 870377..880817
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4712_RS04355 ribE 870419..871054 (+) 636 WP_000493842.1 riboflavin synthase -
  R4712_RS04360 - 871074..872279 (+) 1206 WP_000456639.1 bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II -
  R4712_RS04365 ribE 872280..872747 (+) 468 WP_001099502.1 6,7-dimethyl-8-ribityllumazine synthase -
  R4712_RS04370 hexB 873072..875021 (-) 1950 WP_288176778.1 DNA mismatch repair endonuclease MutL Machinery gene
  R4712_RS04375 - 875164..875289 (+) 126 WP_001813544.1 hypothetical protein -
  R4712_RS04380 brsR 875377..875817 (+) 441 WP_000861956.1 LytTR family DNA-binding domain-containing protein Regulator
  R4712_RS04385 - 875814..876272 (+) 459 WP_000745054.1 DUF3021 domain-containing protein -
  R4712_RS04390 - 876498..877760 (+) 1263 WP_000075789.1 NRAMP family divalent metal transporter -
  R4712_RS04395 nrdI 878053..878523 (-) 471 WP_000849621.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
  R4712_RS04400 - 878601..879134 (-) 534 WP_000729030.1 hypothetical protein -
  R4712_RS04405 - 879186..880472 (-) 1287 WP_000278868.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 146 a.a.        Molecular weight: 17183.84 Da        Isoelectric Point: 5.3783

>NTDB_id=819616 R4712_RS04380 WP_000861956.1 875377..875817(+) (brsR) [Streptococcus pneumoniae strain 16H2041]
MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIKGKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSI
DLRLYQVLKLLPTNFIQISQSEIINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL

Nucleotide


Download         Length: 441 bp        

>NTDB_id=819616 R4712_RS04380 WP_000861956.1 875377..875817(+) (brsR) [Streptococcus pneumoniae strain 16H2041]
ATGAAAGTAGAACTACAGATTAGTGAGACTTACGAGGAGGAAAAGCTGATTGTCCAAGCACCTCAAGAAACCGAAAAAGT
CCAGAAAGTCATCGAGTTCGCAGAAAATCTGGACCAAAGAGAAAAAATCAAAGGAAAAATCGATGATCAGGTCTATCTAG
TTGAGATTGGCAAGATTCAGCGCTTCTATATCGAGAATCGGAAGGTTCTAGCAGAAACCGCGAGTCAGACCTACAGCATT
GATTTGCGACTCTATCAGGTTCTTAAACTCTTGCCAACCAATTTTATCCAAATTTCCCAATCAGAAATCATCAATATCGA
TTCCATCTCTCACCTCAAGCTCACGCCAAACGGTCTGGTAGAAATTTTCTTGAAAAACGAAAGCTTCACCTACTCTTCAC
GCCGTTATCTAAAAACCATCAAGGAGAAATTAGAACTATGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(50-144)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UNA2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  brsR Streptococcus mutans UA159

36.054

100

0.363