Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   R4712_RS05025 Genome accession   NZ_CP137110
Coordinates   996898..997791 (-) Length   297 a.a.
NCBI ID   WP_000343891.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 16H2041     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 991898..1002791
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4712_RS05000 - 993371..993862 (-) 492 WP_000671990.1 hypothetical protein -
  R4712_RS05005 - 993843..994439 (-) 597 WP_000687787.1 ATP-binding cassette domain-containing protein -
  R4712_RS05010 - 994436..994918 (-) 483 WP_001232094.1 stage II sporulation protein M -
  R4712_RS05015 - 994915..996051 (-) 1137 WP_000698828.1 hypothetical protein -
  R4712_RS05020 - 996058..996354 (-) 297 WP_000837726.1 uberolysin/carnocyclin family circular bacteriocin -
  R4712_RS05025 comR 996898..997791 (-) 894 WP_000343891.1 XRE family transcriptional regulator Regulator
  R4712_RS05030 - 997812..998006 (-) 195 WP_000756776.1 hypothetical protein -
  R4712_RS05035 - 998415..998540 (-) 126 WP_000346297.1 PncF family bacteriocin immunity protein -
  R4712_RS05040 blpU 998543..998773 (-) 231 WP_001093068.1 bacteriocin-like peptide BlpU -
  R4712_RS05045 - 998976..999275 (-) 300 Protein_1007 transposase family protein -
  R4712_RS05050 - 999312..999545 (-) 234 WP_000136449.1 acyl carrier protein -
  R4712_RS05055 plsX 999551..1000543 (-) 993 WP_044812845.1 phosphate acyltransferase PlsX -
  R4712_RS05060 recO 1000540..1001310 (-) 771 WP_000616164.1 DNA repair protein RecO Machinery gene
  R4712_RS05065 - 1001307..1002476 (-) 1170 WP_000366342.1 pyridoxal phosphate-dependent aminotransferase -

Sequence

Protein


Download         Length: 297 a.a.        Molecular weight: 34476.90 Da        Isoelectric Point: 4.6063

>NTDB_id=819620 R4712_RS05025 WP_000343891.1 996898..997791(-) (comR) [Streptococcus pneumoniae strain 16H2041]
MDELKREIGYKIKTIRRSCGKTQIDICGDESELTIRQLARIENGQALATLPKLLLIADKLGVSLQNIVDVKVIEIPKGFL
KLKDELIHSQTYADKGRIERKEAILEEIYENYYENLPEEEQLIVDVTQARFDIYGSSDVTYGLGLVEEYFQQLLKKKYFS
VNDLLIIELYFFCCAMGLEDKEHFEELAQKVLLCSEYEDKDSLVQMEKVLLSLFIQIQTEDSLIYIQTFEKIIAKTRHVF
YRPHLFLLKAKYALFVDKNVAEAESFYEKAISLAELLDDQVLVQKILAEKQIDFPTT

Nucleotide


Download         Length: 894 bp        

>NTDB_id=819620 R4712_RS05025 WP_000343891.1 996898..997791(-) (comR) [Streptococcus pneumoniae strain 16H2041]
ATGGATGAGTTGAAACGTGAAATTGGTTATAAAATCAAAACTATTAGGCGATCTTGTGGAAAAACTCAGATAGATATTTG
TGGTGATGAATCAGAGTTGACGATTCGTCAGCTAGCACGTATTGAAAATGGGCAAGCTTTAGCAACACTTCCTAAATTAT
TATTGATTGCGGATAAACTTGGAGTATCATTACAGAATATTGTGGATGTTAAGGTTATAGAGATTCCAAAAGGATTCCTA
AAACTCAAAGATGAGCTGATTCATTCTCAAACCTACGCTGATAAGGGAAGAATCGAACGAAAAGAAGCTATACTTGAGGA
AATATATGAAAACTATTATGAGAATTTGCCTGAGGAAGAGCAGTTAATTGTGGATGTGACACAAGCTCGTTTTGATATTT
ATGGTAGTTCAGATGTGACCTACGGTTTAGGGTTAGTGGAAGAATATTTCCAGCAGTTATTAAAAAAGAAATATTTTTCT
GTAAATGATTTGTTGATTATTGAATTGTATTTCTTTTGTTGTGCTATGGGATTAGAAGATAAAGAACATTTTGAGGAGTT
AGCTCAAAAAGTATTGCTATGTTCAGAATATGAAGATAAGGATAGCCTAGTTCAGATGGAAAAAGTTCTTCTGAGCCTAT
TTATCCAAATTCAGACAGAAGATAGTCTGATATATATTCAAACATTTGAGAAAATTATTGCTAAAACAAGACATGTTTTT
TACCGACCTCATCTATTTTTGTTAAAGGCGAAATATGCTTTATTTGTAGATAAGAATGTGGCAGAGGCAGAAAGTTTCTA
TGAAAAGGCGATTTCTCTAGCAGAATTGCTAGATGATCAGGTATTAGTTCAGAAAATTTTAGCAGAAAAACAAATAGATT
TCCCAACAACCTGA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(76-290)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus mutans UA159

37

100

0.374