Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   R4699_RS10600 Genome accession   NZ_CP137105
Coordinates   2094002..2094913 (+) Length   303 a.a.
NCBI ID   WP_000904856.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 16H2092     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 2089002..2099913
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4699_RS10570 - 2089172..2089466 (+) 295 Protein_2044 hypothetical protein -
  R4699_RS10575 - 2089622..2090836 (+) 1215 WP_000666469.1 pyridoxal phosphate-dependent aminotransferase -
  R4699_RS10580 rpmH 2090981..2091115 (+) 135 WP_000831905.1 50S ribosomal protein L34 -
  R4699_RS10585 - 2091321..2092292 (+) 972 Protein_2047 DUF1542 domain-containing protein -
  R4699_RS10590 - 2092597..2093370 (+) 774 WP_000575634.1 TatD family hydrolase -
  R4699_RS10595 rnmV 2093370..2093930 (+) 561 WP_000660011.1 ribonuclease M5 -
  R4699_RS10600 comR 2094002..2094913 (+) 912 WP_000904856.1 XRE family transcriptional regulator Regulator
  R4699_RS10605 - 2095233..2095529 (+) 297 WP_000815394.1 lactococcin 972 family bacteriocin -
  R4699_RS10610 - 2095606..2097636 (+) 2031 WP_317786093.1 bacteriocin-associated integral membrane family protein -
  R4699_RS10615 - 2097638..2098279 (+) 642 WP_000565533.1 ABC transporter ATP-binding protein -
  R4699_RS10620 - 2098272..2098580 (+) 309 WP_000333257.1 hypothetical protein -
  R4699_RS10625 rsmA 2098711..2099583 (+) 873 WP_001216856.1 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA -

Sequence

Protein


Download         Length: 303 a.a.        Molecular weight: 35479.78 Da        Isoelectric Point: 4.5324

>NTDB_id=819094 R4699_RS10600 WP_000904856.1 2094002..2094913(+) (comR) [Streptococcus pneumoniae strain 16H2092]
MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPSLPKLDYIARRLGVPVYSLMPDFSALPSAYLELKYQI
LREPIYGKEEEYDKKEACLEEIEDLFYEQLPNEEKVWFEATRATIDVIRSGRPEYGETVLDDYFKTIYDKELFLINELEV
INLYFAIVLTKIKQGQNQIEEINRIHSFLVRLTNHVELIAPEYLFALSNTLFSGLACLDNLSSYDSLGAYIFSLNHIMEK
TQDFQKKPIILMLEWKLSLIINNDYVSAEQFYQKSKLFADIIENSYLVTMLEKQWQEDLKKYL

Nucleotide


Download         Length: 912 bp        

>NTDB_id=819094 R4699_RS10600 WP_000904856.1 2094002..2094913(+) (comR) [Streptococcus pneumoniae strain 16H2092]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGA
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGACTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTTCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATAGAGGATTTATTTTA
TGAGCAACTTCCTAATGAGGAAAAAGTATGGTTTGAAGCTACTAGAGCAACGATAGATGTTATTCGAAGTGGACGACCAG
AATACGGGGAAACCGTACTGGACGATTATTTTAAAACAATTTATGATAAGGAATTGTTTTTGATAAATGAATTAGAAGTT
ATCAACTTATATTTTGCTATAGTGCTTACAAAGATAAAACAAGGTCAAAATCAGATTGAAGAAATTAACAGAATTCATTC
GTTTTTAGTTCGTTTGACAAATCATGTAGAATTAATTGCACCAGAATATCTGTTTGCTTTAAGTAACACTTTGTTTTCGG
GTCTAGCCTGTTTGGATAACTTGTCATCTTATGATTCACTAGGAGCTTATATCTTTAGCCTTAATCATATAATGGAAAAA
ACACAAGATTTCCAGAAGAAACCAATTATATTAATGTTGGAGTGGAAATTATCTCTAATAATAAACAATGATTATGTTTC
TGCCGAACAGTTCTATCAGAAATCGAAGCTATTTGCTGATATAATAGAAAATTCTTATTTAGTTACTATGTTAGAAAAAC
AATGGCAAGAAGATTTAAAAAAATATTTATAA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(70-295)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus mutans UA159

39.189

97.69

0.383
  comR Streptococcus pyogenes MGAS8232

37.5

100

0.376
  comR Streptococcus suis P1/7

37.627

97.36

0.366
  comR Streptococcus suis 05ZYH33

37.627

97.36

0.366