Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   R4699_RS09955 Genome accession   NZ_CP137105
Coordinates   1989475..1989969 (+) Length   164 a.a.
NCBI ID   WP_224781507.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 16H2092     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1984475..1994969
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4699_RS09930 - 1984971..1986101 (+) 1131 WP_000885068.1 N-acetyldiaminopimelate deacetylase -
  R4699_RS09935 - 1986113..1986652 (+) 540 WP_000834319.1 5-formyltetrahydrofolate cyclo-ligase -
  R4699_RS09940 - 1986636..1987313 (+) 678 WP_000658498.1 rhomboid family intramembrane serine protease -
  R4699_RS09945 galU 1987380..1988279 (-) 900 WP_000202228.1 UTP--glucose-1-phosphate uridylyltransferase GalU -
  R4699_RS09950 - 1988301..1989317 (-) 1017 WP_000415108.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -
  R4699_RS09955 comR 1989475..1989969 (+) 495 WP_224781507.1 helix-turn-helix transcriptional regulator Regulator
  R4699_RS09960 - 1990084..1990536 (-) 453 Protein_1952 transposase -
  R4699_RS09965 phoU 1990577..1991227 (-) 651 WP_050104937.1 phosphate signaling complex protein PhoU -
  R4699_RS09970 pstB 1991242..1991994 (-) 753 WP_000536447.1 phosphate ABC transporter ATP-binding protein PstB -
  R4699_RS09975 pstA 1991996..1992811 (-) 816 WP_000049768.1 phosphate ABC transporter permease PstA -
  R4699_RS09980 pstC 1992804..1993667 (-) 864 WP_000165887.1 phosphate ABC transporter permease subunit PstC -
  R4699_RS09985 - 1993785..1994660 (-) 876 WP_000669493.1 substrate-binding domain-containing protein -

Sequence

Protein


Download         Length: 164 a.a.        Molecular weight: 19780.85 Da        Isoelectric Point: 4.8839

>NTDB_id=819079 R4699_RS09955 WP_224781507.1 1989475..1989969(+) (comR) [Streptococcus pneumoniae strain 16H2092]
MIQYMLIIEVNNSGSSCRLREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRPILTKLKYIAERLEVEDYK
LMPSYIELDKEYLELKYFLMRTPTYEDETIAQKKESVFDKIFEEYYDRLPEEERFIIPNYSYLALTNYTVQKLPEKLVEI
LSFW

Nucleotide


Download         Length: 495 bp        

>NTDB_id=819079 R4699_RS09955 WP_224781507.1 1989475..1989969(+) (comR) [Streptococcus pneumoniae strain 16H2092]
TTGATTCAGTATATGCTTATAATAGAGGTAAACAACTCAGGAAGTTCTTGTAGGTTGCGAGAGTTTGGCGAAAAAATTAA
AAGATTACGTTTGGCTAAAAAAATCAGTCGTTCAGAATTTTGTGGTGATGAGTCTGAATTAAGTATCCGTCAATTAATTA
GAATTGAAAATGGAGAATCCAGACCAATACTAACAAAGTTAAAATATATTGCTGAACGTTTGGAGGTTGAAGATTACAAG
TTGATGCCAAGTTATATAGAGTTGGATAAGGAATACCTAGAATTGAAGTATTTCTTGATGAGGACTCCTACATACGAAGA
TGAAACTATCGCCCAAAAGAAAGAGAGTGTTTTTGATAAGATTTTTGAAGAGTATTATGATAGGCTACCTGAGGAAGAAA
GATTTATCATCCCAAATTATTCATATCTGGCACTAACGAACTACACAGTTCAAAAATTACCAGAAAAGCTAGTTGAAATA
CTGTCCTTCTGGTGA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(90-137)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS8232

55.833

73.171

0.409
  comR Streptococcus pyogenes MGAS315

54.167

73.171

0.396
  comR Streptococcus mutans UA159

52.5

73.171

0.384