Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   R4708_RS00700 Genome accession   NZ_CP137104
Coordinates   151236..153224 (-) Length   662 a.a.
NCBI ID   WP_000610410.1    Uniprot ID   C1CR65
Organism   Streptococcus pneumoniae strain LM     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 146236..158224
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4708_RS00660 coaB 146523..147212 (+) 690 WP_000699489.1 phosphopantothenate--cysteine ligase -
  R4708_RS00665 coaC 147224..147775 (+) 552 WP_001284130.1 phosphopantothenoylcysteine decarboxylase -
  R4708_RS00670 - 147759..148322 (+) 564 WP_000747408.1 ECF transporter S component -
  R4708_RS00675 - 148618..149145 (+) 528 WP_001097402.1 ECF transporter S component -
  R4708_RS00680 - 149157..149672 (+) 516 WP_000159178.1 transcription repressor NadR -
  R4708_RS00685 - 149669..150136 (-) 468 WP_000091545.1 8-oxo-dGTP diphosphatase -
  R4708_RS00690 - 150209..150676 (-) 468 WP_000449706.1 GNAT family N-acetyltransferase -
  R4708_RS00695 - 150663..151226 (-) 564 WP_000639833.1 GNAT family N-acetyltransferase -
  R4708_RS00700 uvrB 151236..153224 (-) 1989 WP_000610410.1 excinuclease ABC subunit UvrB Machinery gene
  R4708_RS00705 - 153301..154254 (-) 954 WP_000792112.1 CPBP family intramembrane glutamic endopeptidase -
  R4708_RS00710 - 154424..156589 (+) 2166 WP_000726258.1 ABC transporter substrate-binding protein/permease -
  R4708_RS00715 - 156589..157329 (+) 741 WP_001096313.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 662 a.a.        Molecular weight: 75786.89 Da        Isoelectric Point: 4.6065

>NTDB_id=818873 R4708_RS00700 WP_000610410.1 151236..153224(-) (uvrB) [Streptococcus pneumoniae strain LM]
MINRITDNKFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMGATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYG
EFKEFFPENAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFRVEFFGDEIDRIREVEALTGQVL
GEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQLAVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDG
RSEGEPPYTLLDFFPDDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKNERTFITTLTKKMAEDLTDYFKEMGIKVKYM
HSDIKTLERTEIIRDLRLGVFDVLVGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADT
VTQSMQRAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVSKEEDKEVDINSLNKQERKELVKKLEKQMQEAV
EVLDFELAAQIRDMMLEVKALD

Nucleotide


Download         Length: 1989 bp        

>NTDB_id=818873 R4708_RS00700 WP_000610410.1 151236..153224(-) (uvrB) [Streptococcus pneumoniae strain LM]
ATGATTAACCGCATTACAGATAATAAATTTAAACTAGTATCAAAATATCAACCATCAGGAGATCAACCCCAAGCTATCGA
GCAGTTGGTAGATAATATCGAGGGTGGAGAAAAAGCTCAGATTCTGATGGGGGCGACCGGAACAGGGAAGACCTATACCA
TGAGTCAGGTCATTTCCAAAGTCAATAAACCCACTCTAGTCATTGCCCACAATAAAACTCTGGCTGGTCAGCTCTATGGG
GAGTTCAAGGAATTTTTCCCTGAAAATGCAGTTGAGTACTTCGTATCCTACTATGACTATTACCAGCCAGAAGCCTATGT
CCCTTCTAGTGATACCTATATTGAGAAGGATAGTTCTGTCAATGACGAGATTGACAAGCTTCGTCACTCAGCGACTTCAG
CCCTATTGGAGCGCAATGATGTTATTGTCGTGGCCTCGGTCTCTTGTATCTATGGTCTGGGTTCGCCCAAGGAATACGCT
GATAGTGTCGTTAGTCTCCGTCCAGGTCTTGAAATTTCCCGTGATAAACTCTTGAATGACTTGGTGGATATCCAATTTGA
GCGAAATGATATTGATTTCCAACGGGGAAGATTTCGCGTTCGTGGGGATGTGGTGGAGATTTTCCCTGCTTCCCGTGATG
AACACGCTTTTCGAGTAGAATTTTTTGGAGACGAAATTGACCGTATTCGTGAGGTTGAAGCTTTGACAGGTCAAGTCCTT
GGAGAAGTGGATCATTTAGCGATTTTCCCTGCGACTCACTTTGTGACCAATGACGACCACATGGAAGTTGCTATTGCCAA
GATTCAAGCAGAATTAGAAGAGCAACTAGCTGTCTTTGAAAAGGAAGGCAAACTGCTTGAAGCCCAGCGCTTGAAACAAC
GGACAGAGTACGATATCGAAATGCTGCGTGAGATGGGCTATACCAACGGGGTTGAGAACTATTCACGTCACATGGATGGA
CGGAGCGAAGGAGAGCCTCCTTACACACTTCTTGATTTCTTTCCAGATGATTTCTTAATCATGATTGACGAGAGCCACAT
GACCATGGGACAAATCAAGGGCATGTACAATGGAGACCGTTCTCGTAAGGAAATGTTAGTAAATTACGGTTTCCGTTTGC
CGTCTGCTCTGGACAATCGTCCTCTCCGTCGGGAGGAGTTTGAAAGCCATGTGCACCAGATTGTTTACGTTTCAGCGACA
CCTGGTGACTATGAAAATGAACAGACTGAGACAGTGATTGAGCAAATCATTCGTCCAACGGGACTCTTGGATCCAGAGGT
GGAAGTCCGTCCGACTATGGGACAGATTGATGACCTCTTAGGTGAAATTAATGCTCGTGTTGAGAAGAACGAACGAACCT
TTATCACCACGTTGACCAAGAAAATGGCAGAAGACTTGACCGACTACTTCAAGGAAATGGGTATCAAGGTCAAGTACATG
CACTCGGATATCAAGACATTGGAGCGGACTGAGATTATCCGTGACCTGCGCTTGGGTGTCTTTGATGTCTTGGTCGGAAT
CAACCTCCTTCGTGAAGGGATTGACGTTCCTGAAGTGAGCCTCGTAGCGATTCTTGATGCTGACAAGGAAGGTTTCCTTC
GTAACGAACGTGGACTCATCCAGACCATTGGACGTGCCGCCCGTAACAGTGAAGGTCATGTTATCATGTATGCGGACACG
GTTACCCAGTCTATGCAACGTGCTATCGATGAAACTGCCCGCCGTCGCAAAATCCAGATGGCCTATAATGAAGAGCATGG
TATCGTACCACAGACAATCAAGAAAGAAATCCGTGACCTGATTGCTGTGACCAAGGCAGTTTCTAAGGAAGAAGACAAGG
AAGTTGATATCAATAGCCTCAACAAACAAGAGCGCAAAGAACTTGTTAAGAAACTCGAAAAACAAATGCAAGAAGCCGTC
GAAGTGCTTGACTTTGAACTAGCAGCTCAGATTCGTGATATGATGCTGGAAGTGAAGGCGTTGGATTAG

Domains

Predicted by InterProScan.

Ultra-violet resistance protein B (UvrB)

(556-598)

Helicase conserved C-terminal domain (Helicase_C)

(443-549)

UvrB/uvrC motif (UVR)

(626-660)

Type III restriction enzyme, res subunit (ResIII)

(17-143)

UvrB interaction domain (UvrB_inter)

(164-254)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C1CR65

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

99.547

100

0.995
  uvrB Streptococcus pneumoniae D39

99.547

100

0.995
  uvrB Streptococcus pneumoniae TIGR4

99.396

100

0.994