Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   R8563_RS01870 Genome accession   NZ_AP026917
Coordinates   361721..362353 (+) Length   210 a.a.
NCBI ID   WP_000698434.1    Uniprot ID   Q9S1J7
Organism   Streptococcus pneumoniae strain PZ900700007     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 356721..367353
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8563_RS01845 (PC0007_03580) mvaD 356999..357952 (+) 954 WP_000373457.1 diphosphomevalonate decarboxylase -
  R8563_RS01850 (PC0007_03590) - 357939..358946 (+) 1008 WP_000562425.1 phosphomevalonate kinase -
  R8563_RS01855 (PC0007_03600) fni 358930..359940 (+) 1011 WP_000210625.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  R8563_RS01860 (PC0007_03610) liaF 360017..360715 (+) 699 WP_001224637.1 cell wall-active antibiotics response protein LiaF -
  R8563_RS01865 (PC0007_03620) - 360712..361707 (+) 996 WP_000743659.1 sensor histidine kinase -
  R8563_RS01870 (PC0007_03630) vraR 361721..362353 (+) 633 WP_000698434.1 response regulator transcription factor Regulator
  R8563_RS01875 - 362429..363122 (+) 694 Protein_367 DNA alkylation repair protein -
  R8563_RS01880 (PC0007_03660) - 363272..363511 (+) 240 WP_000754501.1 hypothetical protein -
  R8563_RS01885 (PC0007_03670) cbpG 363592..364413 (+) 822 WP_001100136.1 choline-binding protein CbpG -
  R8563_RS01890 (PC0007_03680) cbpF 364432..365454 (+) 1023 WP_000771059.1 choline-binding protein CbpF -
  R8563_RS01895 - 365582..366930 (-) 1349 Protein_371 IS3 family transposase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23553.03 Da        Isoelectric Point: 4.5791

>NTDB_id=81687 R8563_RS01870 WP_000698434.1 361721..362353(+) (vraR) [Streptococcus pneumoniae strain PZ900700007]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=81687 R8563_RS01870 WP_000698434.1 361721..362353(+) (vraR) [Streptococcus pneumoniae strain PZ900700007]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGATTGGGCTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAATATTCTTGCCAAACT
TGAAGTCAGCGATCGTACCCAGGCGGCTGTCTATGCCTTTCAGCACCATTTGGTGGGGCAAGAGGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9S1J7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41

Multiple sequence alignment