Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvA   Type   Machinery gene
Locus tag   R3H37_RS08640 Genome accession   NZ_CP136948
Coordinates   1760515..1761111 (-) Length   198 a.a.
NCBI ID   WP_011285268.1    Uniprot ID   Q48QW4
Organism   Streptococcus pyogenes strain Spyo01     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1755515..1766111
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R3H37_RS08605 (R3H37_08610) - 1755574..1755879 (-) 306 WP_002982199.1 DUF1292 domain-containing protein -
  R3H37_RS08610 (R3H37_08615) ruvX 1755891..1756310 (-) 420 WP_002982196.1 Holliday junction resolvase RuvX -
  R3H37_RS08615 (R3H37_08620) - 1756307..1756576 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  R3H37_RS08620 (R3H37_08625) spx 1756691..1757089 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  R3H37_RS08625 (R3H37_08630) recA 1757380..1758516 (-) 1137 WP_002992179.1 recombinase RecA Machinery gene
  R3H37_RS08630 (R3H37_08635) cinA 1758605..1759876 (-) 1272 WP_030126182.1 competence/damage-inducible protein A Machinery gene
  R3H37_RS08635 (R3H37_08640) - 1759945..1760505 (-) 561 WP_011018314.1 DNA-3-methyladenine glycosylase I -
  R3H37_RS08640 (R3H37_08645) ruvA 1760515..1761111 (-) 597 WP_011285268.1 Holliday junction branch migration protein RuvA Machinery gene
  R3H37_RS08645 (R3H37_08650) - 1761113..1762333 (-) 1221 WP_053308678.1 MDR family MFS transporter -
  R3H37_RS08650 (R3H37_08655) hexB 1762344..1764326 (-) 1983 WP_053308679.1 DNA mismatch repair endonuclease MutL Machinery gene

Sequence

Protein


Download         Length: 198 a.a.        Molecular weight: 21811.12 Da        Isoelectric Point: 6.2537

>NTDB_id=816485 R3H37_RS08640 WP_011285268.1 1760515..1761111(-) (ruvA) [Streptococcus pyogenes strain Spyo01]
MYDYIKGQLTKITAKYIVVETNGLGYIINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI
GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGNTKARSNKAGNTQLDEAIEAL
LALGYKAAELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide


Download         Length: 597 bp        

>NTDB_id=816485 R3H37_RS08640 WP_011285268.1 1760515..1761111(-) (ruvA) [Streptococcus pyogenes strain Spyo01]
ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAACAAATGGACTAGGCTATAT
TATCAATGTAGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAACTGGTAACCATTTATCTGCATCAAGTGATTCGTG
AGGATGCTCACCTGTTGTTTGGTTTTCACACGGAAGACGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCAGGTATT
GGTCCGACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA
GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG
CTCCACAAGAGACTGGTAATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC
CTTGCCCTCGGTTATAAGGCAGCGGAATTGAAGAAAATTCGTGCCTTCTTTGAAGGAACCTCTGAAACGGCCGAACAATA
CATCAAATCAGCCCTTAAACTATTAATGAAAGGCTAG

Domains

Predicted by InterProScan.

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA N terminal domain (RuvA_N)

(1-61)

RuvA, C-terminal domain (RuvA_C)

(152-196)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q48QW4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvA Streptococcus pneumoniae TIGR4

67.005

99.495

0.667
  ruvA Streptococcus pneumoniae R6

67.005

99.495

0.667
  ruvA Streptococcus pneumoniae D39

67.005

99.495

0.667
  ruvA Bacillus subtilis subsp. subtilis str. 168

41.379

100

0.424