Detailed information NTG0081641

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: R8522_RS10070
• Genome accession: NZ_AP026916
• Coordinates: 1960650..1961549 (-)
• Length: 299 a.a.
• NCBI ID: WP_050122824.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900700006
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1955650..1966549

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8522_RS10045 (PC0006_20230)	rsmA	1955887..1956759 (-)	873	WP_001216878.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
R8522_RS11560 (PC0006_20240)	-	1957145..1957291 (-)	147	WP_000333269.1	hypothetical protein	-
R8522_RS10055 (PC0006_20250)	-	1957284..1957925 (-)	642	WP_000565531.1	ABC transporter ATP-binding protein	-
R8522_RS10060 (PC0006_20260)	-	1957927..1959957 (-)	2031	WP_050122819.1	bacteriocin-associated integral membrane family protein	-
R8522_RS10065 (PC0006_20270)	-	1960034..1960330 (-)	297	WP_000815392.1	lactococcin 972 family bacteriocin	-
R8522_RS10070 (PC0006_20280)	comR	1960650..1961549 (-)	900	WP_050122824.1	helix-turn-helix transcriptional regulator	Regulator
R8522_RS10075 (PC0006_20290)	rnmV	1961621..1962181 (-)	561	WP_000660013.1	ribonuclease M5	-
R8522_RS10080 (PC0006_20300)	-	1962181..1962954 (-)	774	WP_050122828.1	TatD family hydrolase	-
R8522_RS10085 (PC0006_20310)	-	1963259..1964230 (-)	972	Protein_1981	DUF1542 domain-containing protein	-
R8522_RS10090 (PC0006_20320)	rpmH	1964436..1964570 (-)	135	WP_000831905.1	50S ribosomal protein L34	-
R8522_RS10095 (PC0006_20330)	-	1964979..1965932 (+)	954	WP_001155321.1	IS30-like element ISSpn8 family transposase	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35365.15 Da
• Isoelectric Point: 4.8298

>NTDB_id=81641 R8522_RS10070 WP_050122824.1 1960650..1961549(-) (comR) [Streptococcus pneumoniae strain PZ900700006]
MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPSLPKLDYIARRLGVPVYSLMPDFSALPSAYLELKYQI
LREPIYGKEEEYDKKEECLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAKLIGDGFLVKKLTEEWQEDVKKYL

Nucleotide

• Length: 900 bp

>NTDB_id=81641 R8522_RS10070 WP_050122824.1 1960650..1961549(-) (comR) [Streptococcus pneumoniae strain PZ900700006]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGA
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGACTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTTCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGAGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGCCTCAGATTATAGAAAAAGAAGCTTATTCAATAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTCTT
TCTTTTGGAACAGAAGAAGGTAACTCAAATAGAGAATTACTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGTAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGAAGCTAATTGGAGATGGATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (70-291)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	37.755	98.328	0.371
comR	Streptococcus suis P1/7	37.801	97.324	0.368
comR	Streptococcus suis 05ZYH33	37.801	97.324	0.368
comR	Streptococcus pyogenes MGAS8232	36.242	99.666	0.361