Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   R1T10_RS05735 Genome accession   NZ_CP136807
Coordinates   1176792..1178819 (+) Length   675 a.a.
NCBI ID   WP_002226304.1    Uniprot ID   -
Organism   Neisseria meningitidis NMB     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1171792..1183819
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R1T10_RS05720 - 1172166..1172726 (-) 561 WP_002226302.1 CreA family protein -
  R1T10_RS05725 - 1173054..1174859 (+) 1806 WP_002213276.1 peptidoglycan DD-metalloendopeptidase family protein -
  R1T10_RS05730 - 1174979..1176463 (+) 1485 WP_002226303.1 S41 family peptidase -
  R1T10_RS05735 uvrB 1176792..1178819 (+) 2028 WP_002226304.1 excinuclease ABC subunit UvrB Machinery gene
  R1T10_RS05740 - 1178931..1179218 (+) 288 WP_002241665.1 hypothetical protein -
  R1T10_RS05745 trmB 1179399..1180115 (-) 717 WP_017201004.1 tRNA (guanosine(46)-N7)-methyltransferase TrmB -
  R1T10_RS05750 - 1180237..1181640 (-) 1404 WP_017201005.1 tetratricopeptide repeat protein -
  R1T10_RS05755 uvrC 1181913..1183799 (-) 1887 WP_017201006.1 excinuclease ABC subunit UvrC -

Sequence

Protein


Download         Length: 675 a.a.        Molecular weight: 76842.30 Da        Isoelectric Point: 4.9632

>NTDB_id=815845 R1T10_RS05735 WP_002226304.1 1176792..1178819(+) (uvrB) [Neisseria meningitidis NMB]
MEVIRYPDSPFKLHQPFPPAGDQPTAIAGLLEGLSDGLAYQTLLGVTGSGKTYTMANVIAQSGRPAIIMAHNKTLAAQLY
AEMREFFPENAVEYFVSYYDYYQPEAYVPSRDLFIEKDSAINEHIEQMRLSATKNLMTRDDVIIVATVSAIYGIGDPTEY
QQMVLSVKEGDTIEQRDIIATLVSMQYERGDLDFKRGSFRVRGDVIDVYPAESSENALRISLFDDEIDRLDMFDPLSGSL
IQRVGRYTVFPSSHYVTPRDTVLRACESIKEELRERIDFFTKENRPVEQQRIEQRTRFDLEMLYEMGFCKGIENYSRHFS
GKKEGEPPPTLMDYLPDNAIMFIDESHVTVTQIGGMYKGDASRKQNLVDYGFRLPSARDNRPLKFHEFEKVMPQTVFVSA
TPAKYEEEHAGQVVEQVVRPTGLVDPQIIIRPVATQVDDLMSEINDRIQKGERVLVTTLTKRMAEQLTDYYSELGIKVRY
LHSDIDTVERVEIIRDLRLGLFDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSHRSLIQTIGRAARNVNGVAILYAD
KITDSMKAAIDETERRREKQIKFNEEHGIVPQQIKKQVKDIIDGVYHEEDGGKGRRQGKNKVKVSEIHNEEDAVKEIAKL
EKAMQQAARDLQFEEAAVLRDRIRGIKEGLLFGSE

Nucleotide


Download         Length: 2028 bp        

>NTDB_id=815845 R1T10_RS05735 WP_002226304.1 1176792..1178819(+) (uvrB) [Neisseria meningitidis NMB]
ATGGAAGTCATCCGATACCCCGATTCCCCTTTCAAACTCCACCAACCCTTCCCGCCCGCAGGCGACCAGCCTACCGCTAT
TGCCGGCTTGCTCGAAGGGCTTTCAGACGGCCTTGCCTACCAAACCCTGCTCGGCGTAACCGGTTCGGGCAAAACCTACA
CCATGGCGAACGTCATCGCCCAAAGCGGCCGACCCGCCATCATCATGGCGCACAACAAAACCCTTGCCGCCCAGCTTTAT
GCCGAAATGCGCGAGTTTTTCCCTGAAAACGCGGTGGAATATTTCGTCTCCTACTACGACTATTACCAACCCGAAGCCTA
TGTGCCCAGCCGCGACCTGTTCATTGAAAAAGACAGCGCGATCAACGAACATATCGAGCAGATGCGCCTTTCCGCCACCA
AGAACCTGATGACGCGCGACGACGTGATTATCGTCGCCACCGTGTCCGCCATCTACGGTATCGGCGACCCGACCGAGTAT
CAGCAAATGGTGTTGTCCGTTAAAGAAGGCGACACCATTGAGCAGCGCGACATCATCGCCACGCTCGTTTCCATGCAGTA
CGAGCGCGGCGATTTGGACTTTAAACGCGGCAGCTTCCGCGTGCGTGGCGACGTGATTGACGTGTACCCCGCCGAAAGCT
CCGAAAACGCCTTGCGCATCAGCCTGTTTGACGACGAAATCGACCGCCTCGATATGTTCGACCCGCTTTCAGGCAGCCTT
ATCCAGCGCGTCGGCCGCTACACCGTCTTCCCGTCCAGCCATTACGTTACCCCGCGCGATACCGTCTTGCGCGCCTGCGA
GTCCATCAAAGAAGAATTACGTGAACGCATTGATTTCTTTACCAAAGAAAACCGTCCCGTCGAACAACAACGCATCGAAC
AGCGCACCCGCTTTGACCTCGAAATGCTCTACGAAATGGGCTTCTGCAAAGGCATCGAAAATTACTCCCGGCACTTCTCC
GGCAAAAAAGAAGGCGAACCGCCGCCCACGCTGATGGACTACCTGCCTGACAACGCCATCATGTTCATCGACGAAAGCCA
CGTTACCGTCACCCAAATCGGCGGCATGTACAAAGGCGACGCATCGCGCAAGCAAAACCTCGTCGACTACGGCTTCCGCC
TGCCTTCCGCCCGCGACAACCGCCCGCTCAAATTCCATGAATTTGAAAAAGTCATGCCGCAAACTGTCTTCGTTTCCGCC
ACTCCAGCCAAATACGAAGAAGAACACGCCGGACAAGTGGTCGAACAAGTCGTCCGCCCCACAGGGCTGGTCGACCCCCA
AATCATCATCCGCCCCGTCGCCACCCAAGTCGACGACTTAATGAGCGAAATCAACGACCGCATCCAAAAAGGCGAACGCG
TTCTCGTTACCACCCTCACCAAACGCATGGCGGAGCAACTCACCGACTATTACAGCGAACTCGGCATCAAAGTGCGCTAC
CTGCACAGCGACATTGATACCGTAGAGCGCGTTGAAATCATTAGAGATTTACGGCTCGGCCTGTTTGACGTACTCGTCGG
CATCAACCTCTTGCGCGAAGGCCTCGATATCCCCGAAGTCTCCCTCGTCGCCATCCTCGACGCCGACAAAGAAGGCTTCC
TGCGCTCACACCGCAGCCTGATTCAAACCATAGGCCGCGCCGCGCGCAACGTGAACGGCGTCGCGATTCTGTACGCCGAC
AAAATCACCGACTCTATGAAAGCCGCCATCGACGAAACCGAACGCCGCCGTGAAAAACAAATTAAATTCAACGAAGAACA
CGGCATCGTGCCGCAACAGATTAAAAAACAGGTCAAAGACATCATTGACGGCGTGTACCACGAAGAAGACGGTGGTAAAG
GCCGTAGACAAGGCAAAAACAAGGTTAAAGTCAGCGAAATTCACAACGAAGAAGACGCGGTTAAAGAAATCGCCAAACTG
GAAAAAGCCATGCAGCAGGCAGCTAGGGATTTGCAGTTTGAAGAGGCGGCTGTACTGAGGGATAGGATACGGGGGATTAA
GGAAGGGTTGTTGTTTGGGAGTGAGTAA

Domains

Predicted by InterProScan.

Ultra-violet resistance protein B (UvrB)

(557-598)

Type III restriction enzyme, res subunit (ResIII)

(23-144)

UvrB interaction domain (UvrB_inter)

(165-255)

Helicase conserved C-terminal domain (Helicase_C)

(444-549)

UvrB/uvrC motif (UVR)

(635-668)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

55.656

98.222

0.547
  uvrB Streptococcus pneumoniae R6

55.656

98.222

0.547
  uvrB Streptococcus pneumoniae D39

55.656

98.222

0.547