Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   RYQ61_RS06230 Genome accession   NZ_CP136799
Coordinates   1198778..1199410 (+) Length   210 a.a.
NCBI ID   WP_009568138.1    Uniprot ID   T1ZG08
Organism   Streptococcus intermedius strain XH2169     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1193778..1204410
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RYQ61_RS06210 (RYQ61_06210) - 1194212..1194952 (+) 741 WP_003073671.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  RYQ61_RS06215 (RYQ61_06215) stkP 1194949..1196823 (+) 1875 WP_003073669.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  RYQ61_RS06220 (RYQ61_06220) liaF 1197086..1197784 (+) 699 WP_009568136.1 cell wall-active antibiotics response protein LiaF -
  RYQ61_RS06225 (RYQ61_06225) - 1197781..1198776 (+) 996 WP_082311763.1 sensor histidine kinase -
  RYQ61_RS06230 (RYQ61_06230) vraR 1198778..1199410 (+) 633 WP_009568138.1 response regulator transcription factor Regulator
  RYQ61_RS06235 (RYQ61_06235) - 1199450..1200850 (+) 1401 WP_102567792.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  RYQ61_RS06240 (RYQ61_06240) - 1200852..1201244 (+) 393 WP_003073658.1 S1 RNA-binding domain-containing protein -
  RYQ61_RS06245 (RYQ61_06245) - 1201364..1201681 (-) 318 WP_102567839.1 DUF960 domain-containing protein -
  RYQ61_RS06250 (RYQ61_06250) - 1201801..1202334 (-) 534 WP_003073655.1 DUF402 domain-containing protein -
  RYQ61_RS06255 (RYQ61_06255) recX 1202421..1203197 (-) 777 WP_102567791.1 recombination regulator RecX Regulator
  RYQ61_RS06260 (RYQ61_06260) - 1203261..1204037 (-) 777 WP_102567790.1 aminoglycoside 3'-phosphotransferase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23710.39 Da        Isoelectric Point: 4.8916

>NTDB_id=815676 RYQ61_RS06230 WP_009568138.1 1198778..1199410(+) (vraR) [Streptococcus intermedius strain XH2169]
MQILLVDDHEMVRLGLKSYLDVQNDVDMVVEASNGCEGVEKALSLRPDVIMMDIVMPKMNGIEATLAILKEWPEAKILIL
TSYLDNEKIYPVLDAGAKGYMLKTSSADDILRAVRKVAKGELAIETEVSQKVEYHRNHIELHEELTARERDILGLLAKGY
ENQRIADELFISLKTVKTHVSNILSKLEVSDRTQAVVYAFQHHLVPQDDI

Nucleotide


Download         Length: 633 bp        

>NTDB_id=815676 RYQ61_RS06230 WP_009568138.1 1198778..1199410(+) (vraR) [Streptococcus intermedius strain XH2169]
ATGCAGATTTTATTAGTAGATGATCATGAAATGGTGCGACTTGGTTTGAAGAGCTATTTGGATGTACAAAATGATGTTGA
TATGGTGGTAGAAGCTTCAAATGGTTGTGAAGGGGTGGAAAAGGCTCTGTCATTACGACCAGATGTGATAATGATGGATA
TTGTCATGCCTAAAATGAATGGGATTGAAGCTACACTTGCTATTTTAAAAGAATGGCCTGAAGCTAAAATTCTTATTTTG
ACTTCTTATTTAGATAATGAAAAAATTTACCCAGTTTTAGATGCAGGGGCTAAAGGATACATGCTTAAAACATCTAGTGC
TGACGATATCTTACGAGCAGTTCGAAAGGTAGCCAAGGGTGAACTTGCTATTGAAACAGAGGTCAGTCAGAAAGTGGAAT
ACCATCGAAATCATATTGAATTACATGAAGAGCTAACAGCGCGTGAGCGCGATATTTTAGGTCTATTAGCAAAAGGGTAT
GAAAATCAACGGATAGCAGATGAGTTGTTTATTTCGTTGAAGACTGTTAAAACACATGTATCTAATATCTTATCAAAATT
AGAAGTAAGTGATCGGACACAAGCTGTTGTTTACGCCTTTCAGCACCACCTTGTCCCACAAGATGACATTTAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB T1ZG08

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

53.883

98.095

0.529
  degU Bacillus subtilis subsp. subtilis str. 168

38.839

100

0.414