Detailed information NTG0813770

Bioinformatically predicted

Overview

• Name: micB
• Type: Regulator
• Locus tag: QBE57_RS02245
• Genome accession: NZ_CP121670
• Coordinates: 445386..446735 (+)
• Length: 449 a.a.
• NCBI ID: WP_002935841.1
• Uniprot ID: G7SGQ2
• Organism: Streptococcus suis strain HBXY-SL
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 440386..451735

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QBE57_RS02220	-	441497..442156 (-)	660	WP_002935828.1	amino acid ABC transporter permease	-
QBE57_RS02225	-	442171..442869 (-)	699	WP_012028333.1	amino acid ABC transporter permease	-
QBE57_RS02230	-	442884..443723 (-)	840	WP_012027305.1	transporter substrate-binding domain-containing protein	-
QBE57_RS02235	-	443734..444495 (-)	762	WP_012027304.1	amino acid ABC transporter ATP-binding protein	-
QBE57_RS02240	micA	444689..445393 (+)	705	WP_004298854.1	response regulator YycF	Regulator
QBE57_RS02245	micB	445386..446735 (+)	1350	WP_002935841.1	cell wall metabolism sensor histidine kinase VicK	Regulator
QBE57_RS02250	vicX	446742..447545 (+)	804	WP_024410918.1	MBL fold metallo-hydrolase	Regulator
QBE57_RS02255	vga(F)	447800..449185 (+)	1386	WP_171935704.1	ABC-F type ribosomal protection protein Vga(F)	-
QBE57_RS02260	pbp2b	449300..451345 (+)	2046	WP_216655091.1	penicillin-binding protein PBP2B	-

Sequence

Protein

• Length: 449 a.a.
• Molecular weight: 51039.08 Da
• Isoelectric Point: 4.5202

>NTDB_id=813770 QBE57_RS02245 WP_002935841.1 445386..446735(+) (micB) [Streptococcus suis strain HBXY-SL]
MINQLRYLMTTAEFWFVVILIGFLIALTVLLIENYRDNKQIKQLNQKVNALIEGNYADVLDMRGSPEITDMANSLNDLSE
VIRLTHDNLEQEKTRLTSILSYMSDGVIATDRIGRIIMINDMAQKQLGLSSQKQEQYHLLEVLDLSDRYTLRDLLAQTPE
IVIDHTNENEEFLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMMRMITDLLSLSRIDNQVGQIDVELINFTAFVTFILNRFDQMKNADSDKVYTIVRDYQISPIW
VEIDTDKMTQVLDNILNNAIKYSPDGGTITFSMKTTDSQLIVSVSDEGLGIPKADLPRIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGHGSTFTIVLPYSKDIALDEWDDSDEEE

Nucleotide

• Length: 1350 bp

>NTDB_id=813770 QBE57_RS02245 WP_002935841.1 445386..446735(+) (micB) [Streptococcus suis strain HBXY-SL]
ATGATTAATCAATTACGTTATTTAATGACCACGGCAGAATTTTGGTTTGTTGTCATTTTGATTGGCTTTCTAATTGCTCT
GACGGTCCTTTTGATTGAAAACTATCGGGATAATAAGCAAATTAAACAACTCAATCAAAAAGTCAACGCCTTAATTGAGG
GGAATTATGCAGATGTGTTAGACATGAGGGGAAGTCCTGAAATCACAGACATGGCGAATTCTCTTAATGATCTGTCCGAG
GTCATCCGCTTAACTCATGATAATTTAGAACAAGAAAAGACGCGTCTGACTTCCATCTTGTCCTATATGAGTGACGGTGT
TATTGCTACAGACCGTATCGGACGGATCATCATGATTAACGATATGGCCCAGAAACAGTTGGGGCTTTCTAGCCAAAAGC
AGGAGCAGTATCACCTGCTCGAGGTTTTAGATTTATCAGATCGTTACACATTGAGAGATTTGTTGGCTCAGACACCTGAG
ATTGTGATTGATCACACCAATGAAAACGAAGAATTTCTGACTTTACGCGCTAATTTTGCCACGATTCGTAGTGAGAGTGG
TCTGATTTCTGGCTTGGTTGTCGTCTTACATGATATGACCGAGCAGGCCAAGGAAGAACGGGAACGTAGGCTGTTTGTGT
CAAATGTGAGTCATGAATTGCGTACGCCATTGACTTCCGTCAAATCCTATCTAGAGGCTCTGGATGAGGGAGCGCTGACG
GAGTCTGTTGCACCGAGTTTTGTTAAGGTATCCTTAGATGAGACCAACCGCATGATGCGGATGATTACAGATCTCCTAAG
CTTATCGCGTATTGATAATCAAGTTGGTCAGATAGATGTTGAACTGATAAACTTTACTGCTTTTGTGACCTTTATTCTTA
ACCGTTTTGACCAAATGAAAAATGCTGATTCTGATAAGGTCTATACGATTGTTCGTGACTATCAAATCAGTCCTATTTGG
GTTGAGATTGATACAGATAAGATGACTCAGGTTTTGGATAATATCTTAAATAATGCCATTAAATATTCGCCAGATGGCGG
GACAATTACCTTCAGCATGAAGACCACAGATAGTCAGTTGATTGTATCCGTCTCAGACGAAGGTCTGGGGATTCCGAAAG
CAGATTTACCTAGAATTTTTGACCGATTTTATCGCGTGGACAAGGCACGATCTCGTGCTCAAGGCGGTACAGGTCTTGGT
TTAGCTATTGCAAAAGAAATCGTGAAACAACATAAGGGCTTTATCTGGGCTAAAAGCGAATATGGTCATGGCTCAACGTT
TACAATTGTCTTGCCGTACAGCAAGGACATCGCACTAGATGAGTGGGATGATTCAGATGAGGAAGAATAG

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (324-434)

• PAS fold (PAS) (96-199)

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

3D structure

• AlphaFold DB: G7SGQ2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
micB	Streptococcus pneumoniae Cp1015	70.183	97.105	0.682
vicK	Streptococcus mutans UA159	70.72	89.755	0.635