Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   F6I35_RS04535 Genome accession   NZ_CP136160
Coordinates   866478..868466 (+) Length   662 a.a.
NCBI ID   WP_024052272.1    Uniprot ID   A0A412PMG2
Organism   Streptococcus anginosus strain UMB8616     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 861478..873466
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F6I35_RS04520 (F6I35_0004520) - 862342..863082 (-) 741 WP_070241651.1 amino acid ABC transporter ATP-binding protein -
  F6I35_RS04525 (F6I35_0004525) - 863082..865265 (-) 2184 WP_150867009.1 ABC transporter substrate-binding protein/permease -
  F6I35_RS04530 (F6I35_0004530) - 865428..866387 (+) 960 WP_070815113.1 CPBP family intramembrane glutamic endopeptidase -
  F6I35_RS04535 (F6I35_0004535) uvrB 866478..868466 (+) 1989 WP_024052272.1 excinuclease ABC subunit UvrB Machinery gene
  F6I35_RS04540 (F6I35_0004540) - 868497..869042 (+) 546 WP_070241648.1 DUF1697 domain-containing protein -
  F6I35_RS04545 (F6I35_0004545) pptA 869172..869915 (+) 744 WP_070241647.1 ABC transporter ATP-binding protein Regulator
  F6I35_RS04550 (F6I35_0004550) - 869905..871545 (+) 1641 WP_150867007.1 hypothetical protein -
  F6I35_RS04555 (F6I35_0004555) hemW 871671..872801 (+) 1131 WP_024052268.1 radical SAM family heme chaperone HemW -

Sequence

Protein


Download         Length: 662 a.a.        Molecular weight: 75735.65 Da        Isoelectric Point: 4.4831

>NTDB_id=812856 F6I35_RS04535 WP_024052272.1 866478..868466(+) (uvrB) [Streptococcus anginosus strain UMB8616]
MINRITDNKFKLVSKYEPSGDQPQAIEQLVDNIEGGEKAQILMGATGTGKTYTMSQVIQKVNKPTLVIAHNKTLAGQLYG
EFKEFFPDNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYS
DSVVSLRPGLEISRDQLLNDLVDIQFERNDIDFQRGKFRVRGDVVEIFPASRDEHAFRVEFFGDEIDRIREVEVLTGQVL
GEVDHLAIFPATHFMTNDENMEIAIGKIQAELEDQLGFFEREGKLLEAQRLKQRTDYDIEMLREMGYTNGVENYSRHMDG
RSEGEPPYTLLDFFPDDFLIMVDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGDYEREQTDTVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINVRTEKNERTFITTLTKKMAEDLTDYFKEMGVKVKYM
HSDIKTLERTEIIRDLRLGVFDVLVGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADT
ITDSMQKAMDETARRRQIQMAYNEEHGIVPQTIQKEIRDLISVTKSALPDKEEVVDIESLNKQERKDMIKKLEGQMQEAA
GLLDFELAAQIRDMILEIKAVD

Nucleotide


Download         Length: 1989 bp        

>NTDB_id=812856 F6I35_RS04535 WP_024052272.1 866478..868466(+) (uvrB) [Streptococcus anginosus strain UMB8616]
ATGATAAATAGAATTACGGACAATAAATTTAAATTAGTTTCCAAGTATGAGCCTTCAGGAGATCAACCACAGGCGATTGA
GCAATTAGTGGATAATATAGAGGGTGGTGAGAAAGCTCAGATTCTCATGGGAGCGACAGGAACTGGGAAGACCTACACTA
TGAGTCAGGTCATCCAAAAGGTCAATAAACCGACCCTAGTTATCGCTCATAATAAAACCCTGGCTGGTCAGCTCTATGGT
GAGTTTAAGGAGTTTTTTCCTGACAATGCGGTTGAATACTTCGTGTCTTACTATGACTATTACCAACCGGAAGCCTATGT
GCCTTCTAGTGATACCTATATTGAGAAGGACAGCTCGGTCAATGATGAGATTGACAAACTTCGTCACTCAGCAACCTCGG
CTCTCTTGGAGCGCAACGATGTGATTGTTGTGGCATCAGTCAGCTGCATTTATGGTTTGGGCTCGCCTAAGGAATACTCC
GATAGCGTGGTCAGTCTGCGACCTGGTTTAGAGATTTCACGGGATCAACTTCTCAATGATTTGGTTGATATTCAATTTGA
GCGCAATGATATTGACTTTCAGCGGGGAAAATTTCGTGTGCGTGGCGATGTTGTGGAAATCTTCCCAGCTTCTCGCGATG
AACATGCCTTTCGGGTGGAATTTTTCGGTGATGAAATTGACCGCATTCGAGAAGTGGAAGTATTGACAGGTCAAGTGTTG
GGCGAAGTAGACCATTTAGCTATTTTTCCTGCCACTCACTTTATGACCAATGACGAAAATATGGAGATTGCTATTGGCAA
GATTCAAGCGGAATTAGAAGATCAGCTAGGCTTTTTTGAAAGAGAAGGGAAGCTTTTAGAAGCTCAGCGGTTGAAGCAAA
GAACGGACTATGATATTGAAATGCTGCGCGAAATGGGCTACACGAATGGTGTAGAGAATTATTCTCGCCACATGGACGGA
CGGAGTGAAGGTGAGCCACCTTACACTTTATTAGATTTCTTTCCTGATGATTTTTTAATCATGGTAGACGAAAGTCATAT
GACGATGGGGCAGATTAAAGGGATGTACAATGGTGACCGCTCGCGGAAGGAAATGCTGGTCAATTATGGTTTCCGCCTGC
CGTCTGCCTTGGACAATCGTCCGCTGCGTCGGGAAGAATTTGAAAGTCATGTGCACCAGATTGTTTACGTGTCTGCTACA
CCAGGGGATTATGAGCGAGAGCAGACGGATACAGTAATTGAGCAAATTATTCGACCAACTGGACTGCTGGATCCAGAAGT
TGAAGTGCGTCCGACTATGGGGCAAATAGATGATCTTTTAGGGGAAATCAACGTACGTACTGAAAAGAATGAGCGGACTT
TTATCACGACGTTGACTAAAAAGATGGCAGAAGATCTGACGGATTACTTTAAAGAAATGGGTGTCAAGGTCAAGTACATG
CACTCAGACATCAAGACTTTGGAGCGTACCGAGATTATCCGAGACCTGCGCTTGGGTGTTTTTGACGTTCTGGTTGGGAT
TAACCTGCTACGCGAGGGAATTGACGTTCCTGAAGTAAGCTTGGTTGCCATTCTCGATGCCGATAAGGAAGGTTTCCTAC
GTAACGAACGTGGCTTAATCCAGACCATTGGTCGCGCTGCCCGTAATAGTGAAGGCCACGTCATCATGTATGCTGACACG
ATCACAGATTCCATGCAAAAAGCTATGGATGAAACCGCCCGTCGTCGTCAGATTCAAATGGCTTATAATGAAGAACATGG
TATTGTACCGCAAACAATCCAGAAAGAAATCCGTGACCTAATCAGTGTGACAAAATCTGCTCTACCAGACAAGGAAGAAG
TGGTAGATATTGAAAGTCTTAACAAGCAGGAACGTAAAGATATGATTAAGAAACTAGAGGGACAAATGCAAGAAGCGGCT
GGTCTTTTGGATTTCGAACTTGCCGCTCAAATTCGCGATATGATTTTGGAGATTAAGGCGGTGGATTAG

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(626-660)

Helicase conserved C-terminal domain (Helicase_C)

(445-549)

Type III restriction enzyme, res subunit (ResIII)

(17-143)

Ultra-violet resistance protein B (UvrB)

(556-598)

UvrB interaction domain (UvrB_inter)

(164-254)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A412PMG2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

92.145

100

0.921
  uvrB Streptococcus pneumoniae D39

92.145

100

0.921
  uvrB Streptococcus pneumoniae TIGR4

91.994

100

0.92