Detailed information NTG0812844

Bioinformatically predicted

Overview

• Name: comFA
• Type: Machinery gene
• Locus tag: QA712_RS01345
• Genome accession: NZ_CP121539
• Coordinates: 138261..139583 (-)
• Length: 440 a.a.
• NCBI ID: WP_372757356.1
• Uniprot ID: -
• Organism: Lactococcus lactis strain MA5
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 133261..144583

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QA712_RS01315 (QA712_01295)	-	134404..135372 (+)	969	WP_003130649.1	PhoH family protein	-
QA712_RS01320 (QA712_01300)	-	135430..135915 (+)	486	WP_311802577.1	NUDIX hydrolase	-
QA712_RS01325 (QA712_01305)	ybeY	136061..136549 (+)	489	WP_003130652.1	rRNA maturation RNase YbeY	-
QA712_RS01330 (QA712_01310)	-	136533..136988 (+)	456	WP_003130653.1	diacylglycerol kinase family protein	-
QA712_RS01335 (QA712_01315)	-	137002..137580 (+)	579	WP_047206265.1	nucleotidyltransferase family protein	-
QA712_RS01340	-	137614..138264 (-)	651	WP_317366878.1	ComF family protein	-
QA712_RS01345 (QA712_01325)	comFA	138261..139583 (-)	1323	WP_372757356.1	DEAD/DEAH box helicase	Machinery gene
QA712_RS01350 (QA712_01330)	-	139640..140269 (+)	630	WP_003130660.1	YigZ family protein	-
QA712_RS01355 (QA712_01335)	-	140403..140900 (+)	498	WP_003130662.1	VanZ family protein	-
QA712_RS01360 (QA712_01340)	-	140948..141967 (+)	1020	WP_012897709.1	DUF475 domain-containing protein	-
QA712_RS01365 (QA712_01345)	-	142082..142828 (+)	747	WP_372757358.1	bifunctional metallophosphatase/5'-nucleotidase	-
QA712_RS01370 (QA712_01350)	glyQ	143114..144067 (+)	954	WP_003130667.1	glycine--tRNA ligase subunit alpha	-

Sequence

Protein

• Length: 440 a.a.
• Molecular weight: 50201.71 Da
• Isoelectric Point: 10.1470

>NTDB_id=812844 QA712_RS01345 WP_372757356.1 138261..139583(-) (comFA) [Lactococcus lactis strain MA5]
MSTNQEKLFGRLLLKNNILQLIKSTDKISVSKIFSNFLLEAKVNPILGMTSISSNKIKCNRCGTAHIKNSVKLPIGVFYC
PSCIQLGRVRSDEFLYFLPQKNFPKKSYINWSGKLTENQKSISNALCQEINSHQQIIVQAVTGAGKTEMIYQVIEQILEK
GGVVGLASPRIDVCLELHQRLSRDFSCKIPLLYHDGDSYFRAPLIIMTSHQLLRFKEAFDLLIIDEVDAFPFRDNEMLYF
AAEKARKIEGNLIFLTATSTDKLEKDIKKQKLYPLFLPRRFHNFPLVVPKFFWKNKFDKKLIEQRNSGFPLLIFAAEIES
GQEFAKQLQLKFPKEKIAFVASTTKDRLEIVKAFRNKEITILIATSILERGVTFPNVDVFVINSEYPNFTKSSLIQMAGR
VGRSSEHPTGLVSFFHYGKSKAMCQAVREIKKMNQLGGFS

Nucleotide

• Length: 1323 bp

>NTDB_id=812844 QA712_RS01345 WP_372757356.1 138261..139583(-) (comFA) [Lactococcus lactis strain MA5]
ATGAGCACTAATCAAGAAAAGTTATTTGGCCGTTTATTATTAAAAAATAATATTTTACAACTTATAAAAAGTACTGACAA
GATTTCTGTCAGTAAAATTTTTAGTAATTTTTTGTTAGAAGCGAAGGTGAATCCAATTTTGGGAATGACTTCAATTTCTT
CCAATAAAATAAAATGCAACCGTTGTGGGACTGCTCATATAAAAAATTCTGTCAAACTTCCAATTGGTGTATTTTACTGT
CCAAGTTGTATTCAATTAGGTCGAGTCCGCTCCGATGAATTCTTGTACTTTCTGCCACAAAAGAATTTCCCAAAGAAATC
ATATATAAACTGGTCGGGAAAACTGACAGAGAATCAAAAATCAATTTCAAATGCCCTCTGTCAGGAAATTAATTCTCATC
AGCAAATAATTGTCCAAGCTGTGACTGGGGCTGGAAAAACTGAAATGATTTATCAAGTCATTGAGCAAATTTTAGAAAAA
GGTGGAGTTGTTGGTCTAGCTAGTCCAAGAATTGATGTTTGTCTTGAACTTCATCAGCGATTATCACGTGATTTTTCCTG
TAAGATTCCACTCTTATATCATGATGGCGACAGCTATTTCCGAGCTCCATTAATAATAATGACCAGTCATCAGCTTTTAC
GCTTCAAGGAAGCTTTTGATTTGCTGATTATTGATGAGGTTGATGCCTTTCCCTTTAGAGATAATGAAATGCTTTATTTT
GCGGCAGAAAAAGCAAGAAAAATAGAAGGGAATTTAATATTTTTGACCGCAACTTCTACTGACAAACTTGAAAAAGATAT
AAAAAAGCAAAAACTCTATCCTTTGTTTCTGCCGCGTCGTTTTCACAATTTTCCTTTAGTGGTGCCTAAATTTTTTTGGA
AAAATAAATTTGATAAGAAATTAATTGAGCAAAGAAATAGTGGCTTTCCACTTCTAATTTTTGCTGCTGAAATTGAATCT
GGACAAGAATTTGCAAAACAACTACAACTAAAATTTCCTAAAGAAAAAATTGCTTTCGTTGCTTCAACAACAAAAGATAG
ATTGGAAATTGTTAAAGCTTTTAGAAATAAAGAAATTACTATTTTAATAGCGACATCAATTCTTGAACGGGGAGTCACTT
TTCCAAATGTTGATGTTTTTGTCATCAACAGTGAGTACCCAAACTTCACTAAATCCTCACTGATACAAATGGCTGGACGT
GTAGGTCGTAGTTCTGAGCATCCAACAGGCTTAGTTAGTTTTTTTCATTACGGAAAATCCAAAGCAATGTGTCAGGCAGT
TAGAGAAATCAAAAAAATGAATCAACTTGGAGGTTTTTCATGA

Domains

Predicted by InterproScan.

• Helicase conserved C-terminal domain (Helicase_C) (300-404)

• Type III restriction enzyme, res subunit (ResIII) (114-226)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comFA	Lactococcus lactis subsp. cremoris KW2	74	90.909	0.673
comFA/cflA	Streptococcus pneumoniae Rx1	52.764	90.455	0.477
comFA/cflA	Streptococcus pneumoniae D39	52.764	90.455	0.477
comFA/cflA	Streptococcus pneumoniae R6	52.764	90.455	0.477
comFA/cflA	Streptococcus pneumoniae TIGR4	52.764	90.455	0.477
comFA/cflA	Streptococcus mitis SK321	52.513	90.455	0.475
comFA/cflA	Streptococcus mitis NCTC 12261	51.508	90.455	0.466
comFA	Bacillus subtilis subsp. subtilis str. 168	36.83	100	0.375