Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   P8P68_RS07295 Genome accession   NZ_CP121467
Coordinates   1487208..1488506 (+) Length   432 a.a.
NCBI ID   WP_278275829.1    Uniprot ID   A0AAX3TIS1
Organism   Streptococcus sp. D7B5     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1482208..1493506
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P8P68_RS07270 (P8P68_07270) rpsB 1483046..1483825 (+) 780 WP_000268475.1 30S ribosomal protein S2 -
  P8P68_RS07275 (P8P68_07275) tsf 1483905..1484945 (+) 1041 WP_278275825.1 translation elongation factor Ts -
  P8P68_RS07280 (P8P68_07280) cysK 1485034..1485960 (-) 927 WP_278275826.1 cysteine synthase A -
  P8P68_RS07285 (P8P68_07285) - 1486057..1486500 (-) 444 WP_278275827.1 PH domain-containing protein -
  P8P68_RS07290 (P8P68_07290) - 1486516..1487151 (-) 636 WP_278275828.1 YigZ family protein -
  P8P68_RS07295 (P8P68_07295) comFA/cflA 1487208..1488506 (+) 1299 WP_278275829.1 DEAD/DEAH box helicase Machinery gene
  P8P68_RS07300 (P8P68_07300) comFC/cflB 1488503..1489165 (+) 663 WP_000995720.1 ComF family protein Machinery gene
  P8P68_RS07305 (P8P68_07305) raiA 1489245..1489793 (+) 549 WP_000599111.1 ribosome-associated translation inhibitor RaiA -
  P8P68_RS07310 (P8P68_07310) - 1489875..1491053 (+) 1179 WP_000656057.1 acetyl-CoA C-acetyltransferase -
  P8P68_RS07315 (P8P68_07315) - 1491210..1493183 (+) 1974 WP_278275830.1 DHH family phosphoesterase -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49463.44 Da        Isoelectric Point: 8.3096

>NTDB_id=812246 P8P68_RS07295 WP_278275829.1 1487208..1488506(+) (comFA/cflA) [Streptococcus sp. D7B5]
MKVNPNYLGRLFTEKELTKEERQMAVKLPAMRKEKGKLFCQRCNSSILEEWHLPVGAYYCRECLLMKRVRSDQALYYFPQ
EDFPKQDVLKWRGQLTPFQEKVSEGLLQAVDKQEPTLVHAVTGAGKTEMIYQVVAKVINEGGAVCLASPRIDVCLELYKR
LQNDFACEIALIHGESEPYFRTPLVVATTHQLLKFYHAFDLLIVDEVDAFPYVDNSVLYYAVNKCVKEEGLRIFLTATST
DELDKKVRTGELKRLSLPRRFHGNPLIIPKPVWLSDFNCYLDKSQLSPKLKTYIEKQRRTGFPLLLFASEIQKGEKLKEI
LQEQFPNENIGFVSSVTVDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGGRVGRSMDR
PTGELLFFHDGLNASIKKAIKEIKQMNKEAGL

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=812246 P8P68_RS07295 WP_278275829.1 1487208..1488506(+) (comFA/cflA) [Streptococcus sp. D7B5]
ATGAAAGTAAATCCAAATTACCTCGGTCGCTTGTTTACTGAGAAAGAATTAACGAAAGAAGAACGTCAGATGGCGGTGAA
ACTGCCGGCAATGAGAAAAGAGAAAGGGAAACTGTTTTGTCAACGTTGTAATAGTAGTATTCTAGAAGAATGGCATTTAC
CTGTAGGTGCTTACTATTGTAGGGAGTGTTTATTGATGAAGAGGGTCAGGAGTGATCAAGCTTTATACTATTTTCCGCAG
GAGGATTTTCCTAAGCAAGACGTCCTCAAATGGCGTGGTCAGTTAACACCTTTTCAAGAAAAAGTTTCAGAGGGACTTCT
TCAAGCGGTAGACAAGCAAGAGCCAACCTTGGTTCACGCTGTAACAGGAGCGGGAAAGACAGAGATGATTTATCAAGTTG
TGGCTAAAGTGATTAATGAAGGTGGTGCAGTTTGTTTAGCCAGCCCTCGAATTGATGTGTGTTTGGAGCTGTATAAACGA
CTGCAGAATGACTTTGCTTGTGAGATAGCACTAATTCATGGTGAGTCAGAACCCTATTTTCGAACACCACTAGTTGTTGC
AACGACTCATCAGCTGTTAAAATTTTATCATGCTTTTGACTTGCTGATAGTGGATGAAGTAGATGCCTTTCCTTATGTTG
ACAACTCTGTTCTTTACTATGCTGTAAACAAATGTGTAAAGGAGGAGGGGTTAAGGATATTTCTTACAGCGACCTCTACA
GATGAGTTAGATAAAAAGGTTCGCACTGGAGAATTAAAAAGGTTAAGCTTGCCAAGACGATTTCATGGAAATCCATTGAT
TATTCCAAAGCCAGTTTGGTTATCGGATTTTAATTGTTATTTAGATAAGAGTCAGTTATCTCCAAAGTTAAAAACCTATA
TAGAGAAACAGAGGAGGACCGGTTTTCCATTACTGCTTTTTGCATCAGAAATTCAGAAAGGTGAGAAGTTGAAAGAAATC
CTGCAGGAGCAGTTCCCGAATGAGAATATTGGTTTTGTGTCCTCTGTTACAGTAGATCGATTAGAGCAGGTGCAAGCTTT
TCGAGATGGAGAACTAACAATACTGATCAGTACAACAATATTGGAACGCGGAGTCACCTTCCCTTGTGTGGATGTTTTCG
TAGTAGAAGCTAATCATCGACTCTTTACCAAGTCTAGCTTGATTCAGATTGGTGGTCGAGTTGGACGTAGTATGGACAGA
CCAACTGGTGAGTTGCTCTTCTTTCATGATGGGTTAAATGCTTCCATCAAGAAGGCAATCAAGGAAATCAAGCAGATGAA
CAAGGAGGCGGGATTATGA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(94-209)

Helicase conserved C-terminal domain (Helicase_C)

(294-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

89.815

100

0.898
  comFA/cflA Streptococcus pneumoniae Rx1

89.815

100

0.898
  comFA/cflA Streptococcus pneumoniae D39

89.815

100

0.898
  comFA/cflA Streptococcus pneumoniae R6

89.815

100

0.898
  comFA/cflA Streptococcus pneumoniae TIGR4

89.583

100

0.896
  comFA/cflA Streptococcus mitis SK321

89.12

100

0.891
  comFA Lactococcus lactis subsp. cremoris KW2

51.1

94.676

0.484
  comFA Latilactobacillus sakei subsp. sakei 23K

39.091

100

0.398