Detailed information NTG0812227

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: P8P68_RS05955
• Genome accession: NZ_CP121467
• Coordinates: 1234903..1235913 (-)
• Length: 336 a.a.
• NCBI ID: WP_001090635.1
• Uniprot ID: I0Q241
• Organism: Streptococcus sp. D7B5
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1229903..1240913

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P8P68_RS05940 (P8P68_05940)	-	1229950..1231935 (-)	1986	WP_278275762.1	CAP domain-containing protein	-
P8P68_RS05945 (P8P68_05945)	-	1232432..1233823 (-)	1392	WP_000453118.1	Cof-type HAD-IIB family hydrolase	-
P8P68_RS05950 (P8P68_05950)	-	1233889..1234851 (+)	963	WP_001124799.1	asparaginase	-
P8P68_RS05955 (P8P68_05955)	ccpA	1234903..1235913 (-)	1011	WP_001090635.1	catabolite control protein A	Regulator
P8P68_RS05960 (P8P68_05960)	-	1236118..1236435 (+)	318	WP_000886044.1	DUF960 domain-containing protein	-
P8P68_RS05965 (P8P68_05965)	-	1236486..1237769 (-)	1284	WP_278275763.1	DUF308 domain-containing protein	-
P8P68_RS05970 (P8P68_05970)	folK	1237762..1238583 (-)	822	WP_278275764.1	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	-
P8P68_RS05975 (P8P68_05975)	folE	1238742..1239296 (-)	555	WP_000380931.1	GTP cyclohydrolase I FolE	-
P8P68_RS05980 (P8P68_05980)	-	1239277..1240599 (-)	1323	WP_278275765.1	folylpolyglutamate synthase/dihydrofolate synthase family protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37214.23 Da
• Isoelectric Point: 5.5033

>NTDB_id=812227 P8P68_RS05955 WP_001090635.1 1234903..1235913(-) (ccpA) [Streptococcus sp. D7B5]
MNTDDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
TLAKGIDDIAEMYKYNIVLANSDEDDEKEVSVVNTLFSKQVDGIIFMGYHLTEKIRSEFSRSRTPVVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLLKENEKIAFVSGPLVDDINGKVRLIGYKEALKKAGHSYSEGLVFESKYSYDDGYALAERLISSQ
ATAAVVTGDELAAGVLNGLADHGVSVPEEFEIITTDDSQIARFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERRSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=812227 P8P68_RS05955 WP_001090635.1 1234903..1235913(-) (ccpA) [Streptococcus sp. D7B5]
ATGAACACAGATGATACAGTAACGATTTATGACGTCGCCCGTGAAGCAGGAGTTTCAATGGCAACAGTTAGCCGTGTCGT
TAATGGCAACAAGAATGTTAAAGAGAACACTCGAAAAAAAGTCCTAGAAGTGATTGATCGCTTGGACTATCGTCCAAATG
CGGTAGCACGTGGTTTGGCTAGCAAGAAAACAACGACAGTCGGAGTTGTGATTCCTAACATTACCAATGGTTATTTCTCA
ACACTTGCTAAGGGGATTGACGACATTGCTGAAATGTACAAGTATAACATTGTCCTAGCAAATAGTGATGAGGATGATGA
AAAGGAAGTTTCAGTGGTTAACACTCTCTTTTCAAAACAAGTCGATGGGATTATCTTTATGGGCTATCACTTGACTGAAA
AGATTCGTTCAGAATTCTCTCGTTCACGGACACCGGTTGTTCTTGCCGGTACTGTGGATGTAGAACACCAACTTCCAAGT
GTGAATATTGACTACAAACAAGCAACGATTGATGCCGTGAGCTACCTTCTCAAAGAAAACGAGAAAATTGCTTTTGTGAG
TGGACCACTCGTCGATGATATCAATGGCAAGGTTCGTTTGATTGGTTACAAGGAAGCCTTGAAAAAAGCTGGACATTCTT
ATAGCGAGGGATTGGTCTTTGAATCAAAATACAGCTATGATGATGGTTATGCCTTGGCAGAACGCTTGATTTCATCACAA
GCTACAGCCGCAGTTGTAACAGGCGATGAATTGGCAGCAGGTGTCCTAAATGGTTTGGCTGACCACGGTGTGTCTGTACC
AGAAGAGTTTGAAATCATTACGACAGATGACTCTCAGATTGCACGATTCACTCGTCCAAACTTGACTACTATTGCCCAAC
CTCTTTATGACTTAGGTGCTATCAGCATGCGTATGTTGACTAAGATTATGCATAAGGAAGAATTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGCCGCTCTACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

3D structure

• AlphaFold DB: I0Q241

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	94.345	100	0.943
ccpA	Streptococcus gordonii str. Challis substr. CH1	88.623	99.405	0.881
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568