Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA   Type   Machinery gene
Locus tag   HT081_RS10920 Genome accession   NZ_AP023073
Coordinates   2093178..2094431 (+) Length   417 a.a.
NCBI ID   WP_003696286.1    Uniprot ID   A0AB74ETB0
Organism   Neisseria gonorrhoeae strain TUM15753     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2088178..2099431
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HT081_RS10900 (TUM15753C_20890) - 2088928..2089929 (+) 1002 WP_003686999.1 thiamine ABC transporter substrate-binding protein -
  HT081_RS10905 (TUM15753C_20900) - 2090023..2090871 (+) 849 WP_003687000.1 mechanosensitive ion channel family protein -
  HT081_RS10910 (TUM15753C_20910) - 2090898..2091380 (+) 483 WP_003694396.1 CinA family protein -
  HT081_RS10915 (TUM15753C_20920) msrAB 2091464..2093032 (-) 1569 WP_003694393.1 bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB -
  HT081_RS10920 (TUM15753C_20930) pilA 2093178..2094431 (+) 1254 WP_003696286.1 signal recognition particle-docking protein FtsY Machinery gene
  HT081_RS10925 - 2094545..2094682 (-) 138 WP_172760541.1 hypothetical protein -
  HT081_RS10930 (TUM15753C_20940) - 2094696..2095490 (-) 795 Protein_2119 opacity family porin -
  HT081_RS10935 - 2095417..2095572 (+) 156 WP_172763131.1 hypothetical protein -
  HT081_RS10940 (TUM15753C_20950) pilE 2096084..2096566 (-) 483 WP_172762861.1 pilin Machinery gene
  HT081_RS10945 - 2096935..2097078 (-) 144 WP_172763123.1 hypothetical protein -
  HT081_RS10950 - 2097183..2097263 (-) 81 Protein_2123 pilin -
  HT081_RS10955 (TUM15753C_20960) pilE 2097381..2097800 (-) 420 WP_172760461.1 pilin Machinery gene
  HT081_RS10960 (TUM15753C_20970) lpxC 2097920..2098843 (-) 924 WP_172760462.1 UDP-3-O-acyl-N-acetylglucosamine deacetylase -

Sequence

Protein


Download         Length: 417 a.a.        Molecular weight: 44331.70 Da        Isoelectric Point: 4.8647

>NTDB_id=81103 HT081_RS10920 WP_003696286.1 2093178..2094431(+) (pilA) [Neisseria gonorrhoeae strain TUM15753]
MFSFFRRKKKQETPALEEAQVQETAAKVESEVAQIVGNIKEDVESLAESVKGRAESAVETVSGAVEQVKETVAEMPSEAG
EAAERVESAKEAVAETVGEAVGQVQEAVATTEEHKLGWAARLKQGLAKSRDKMAKSLAGVFGGGQIGEDLYEELETVLIT
GDMGMEATEYLMKDVRGRVSLKGLKDGNELRGALKEALYDLIKPLEKPLVLPETKEPFVIMLAGINGAGKTTSIGKLAKY
FQAQGKSVLLAAGDTFRAAAREQLQAWGGRNNVTVISQTTGDSAAVCFDAVQAAKARGIDIVLADTAGRLPTQLHLMEEI
KKVKRVLQKAIPGAPHEIIVVLDANIGQNAVNQVKAFDDALGLTGLIVTKLDGTAKGGILAALASDRPVPVRYIGVGEGI
DDLRPFDARAFVDALLD

Nucleotide


Download         Length: 1254 bp        

>NTDB_id=81103 HT081_RS10920 WP_003696286.1 2093178..2094431(+) (pilA) [Neisseria gonorrhoeae strain TUM15753]
ATGTTCAGCTTCTTCCGTCGCAAGAAAAAACAGGAAACGCCGGCTCTCGAGGAGGCCCAAGTTCAGGAAACCGCAGCAAA
AGTAGAATCTGAAGTTGCTCAAATAGTTGGAAATATTAAAGAAGATGTCGAATCTTTAGCAGAAAGCGTCAAAGGGCGGG
CCGAATCTGCCGTTGAAACCGTCAGCGGTGCGGTTGAACAGGTAAAGGAAACCGTTGCCGAGATGCCGTCTGAAGCAGGG
GAAGCGGCGGAACGCGTTGAATCCGCAAAAGAAGCTGTTGCCGAAACCGTCGGCGAGGCTGTCGGGCAAGTTCAAGAAGC
CGTTGCGACAACTGAAGAACACAAGCTCGGTTGGGCTGCGCGTTTGAAACAAGGCTTGGCCAAATCACGCGACAAAATGG
CGAAATCGCTGGCCGGCGTGTTCGGCGGCGGACAAATCGGCGAGGATTTGTACGAAGAGCTGGAAACCGTGCTGATTACC
GGCGATATGGGCATGGAGGCCACCGAATACCTGATGAAAGACGTGCGCGGCCGCGTCAGCCTCAAAGGGCTGAAAGACGG
CAACGAATTGCGCGGCGCGTTGAAAGAAGCCTTGTACGACCTGATTAAGCCGTTGGAAAAACCGCTGGTCTTGCCCGAAA
CTAAAGAGCCTTTCGTGATTATGCTTGCCGGTATCAACGGCGCGGGCAAAACCACGTCTATCGGCAAACTCGCCAAATAT
TTCCAAGCGCAGGGCAAATCCGTATTGCTGGCGGCAGGCGATACTTTCCGCGCCGCCGCGCGCGAGCAGCTTCAGGCTTG
GGGCGGGCGCAACAATGTAACCGTGATTTCACAAACCACGGGCGATTCCGCCGCTGTGTGCTTCGATGCCGTCCAAGCCG
CGAAAGCGCGCGGGATCGACATCGTGCTTGCCGACACCGCCGGCCGCCTGCCCACGCAGCTTCATTTGATGGAAGAAATC
AAAAAAGTGAAGCGCGTGCTGCAAAAAGCCATTCCCGGCGCGCCGCACGAAATTATCGTCGTACTCGATGCCAATATCGG
GCAAAACGCCGTCAACCAAGTCAAAGCCTTTGACGACGCATTGGGGCTGACGGGGCTTATCGTTACCAAACTCGACGGCA
CGGCAAAAGGCGGCATCCTCGCCGCGCTTGCTTCCGACCGCCCCGTCCCCGTCCGCTACATCGGCGTGGGCGAAGGCATA
GACGACCTGCGCCCGTTTGACGCGCGTGCGTTTGTGGACGCACTGCTGGATTGA

Domains

Predicted by InterproScan.

SRP54-type protein, GTPase domain (SRP54)

(217-416)

SRP54-type protein, helical bundle domain (SRP54_N)

(132-198)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA Neisseria gonorrhoeae MS11

100

100

1

Multiple sequence alignment