Detailed information
Bioinformatically predicted
Overview
| Name | comP | Type | Machinery gene |
| Locus tag | HT081_RS02155 | Genome accession | NZ_AP023073 |
| Coordinates | 441420..441869 (+) | Length | 149 a.a. |
| NCBI ID | WP_002214937.1 | Uniprot ID | A0AA44U8B7 |
| Organism | Neisseria gonorrhoeae strain TUM15753 | ||
| Function | DNA binding; DNA uptake; receptor of DNA uptake sequence (DUS) (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 434437..488438 | 441420..441869 | within | 0 |
Gene organization within MGE regions
Location: 434437..488438
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HT081_RS02120 (TUM15753C_04030) | - | 434437..435090 (+) | 654 | Protein_399 | TIGR01621 family pseudouridine synthase | - |
| HT081_RS11810 | - | 440716..440835 (+) | 120 | Protein_400 | competence protein ComE | - |
| HT081_RS02150 (TUM15753C_04040) | comE | 440937..441332 (+) | 396 | WP_003703428.1 | helix-hairpin-helix domain-containing protein | Machinery gene |
| HT081_RS02155 (TUM15753C_04050) | comP | 441420..441869 (+) | 450 | WP_002214937.1 | type IV pilin protein | Machinery gene |
| HT081_RS02165 | - | 442779..443369 (+) | 591 | WP_080229150.1 | DNA cytosine methyltransferase | - |
| HT081_RS02170 (TUM15753C_04060) | - | 443366..443737 (+) | 372 | WP_012503918.1 | DNA cytosine methyltransferase | - |
| HT081_RS11815 (TUM15753C_04070) | - | 443751..444608 (+) | 858 | WP_012503917.1 | ATP-binding protein | - |
| HT081_RS11820 (TUM15753C_04080) | - | 444798..445394 (+) | 597 | WP_012503916.1 | TIGR02391 family protein | - |
| HT081_RS02180 (TUM15753C_04090) | - | 445400..445822 (+) | 423 | WP_003691751.1 | very short patch repair endonuclease | - |
| HT081_RS02185 (TUM15753C_04100) | - | 445961..447306 (+) | 1346 | Protein_408 | replication initiation factor domain-containing protein | - |
| HT081_RS02190 (TUM15753C_04110) | - | 447351..447641 (+) | 291 | WP_012503914.1 | hypothetical protein | - |
| HT081_RS02195 (TUM15753C_04120) | - | 447646..447843 (+) | 198 | WP_003689600.1 | hypothetical protein | - |
| HT081_RS02200 (TUM15753C_04130) | - | 447917..448135 (+) | 219 | WP_003691584.1 | major capsid protein | - |
| HT081_RS02205 | - | 448142..448420 (+) | 279 | WP_003691583.1 | hypothetical protein | - |
| HT081_RS02210 (TUM15753C_04140) | - | 448548..448865 (+) | 318 | WP_003689167.1 | DUF1132 family protein | - |
| HT081_RS02215 | - | 448807..450360 (+) | 1554 | Protein_414 | IgG-binding virulence factor TspB family protein | - |
| HT081_RS02220 (TUM15753C_04150) | - | 450374..450664 (+) | 291 | WP_017147034.1 | DUF2523 domain-containing protein | - |
| HT081_RS02225 (TUM15753C_04160) | - | 450674..451759 (+) | 1086 | WP_003698930.1 | zonular occludens toxin domain-containing protein | - |
| HT081_RS02230 (TUM15753C_04170) | - | 451880..452239 (+) | 360 | WP_003689732.1 | hypothetical protein | - |
| HT081_RS02235 (TUM15753C_04180) | - | 452871..453833 (-) | 963 | WP_172763125.1 | IS110 family transposase | - |
| HT081_RS02240 | - | 453836..454018 (-) | 183 | Protein_419 | glycosyltransferase | - |
| HT081_RS02245 (TUM15753C_04190) | ribA | 454186..454779 (-) | 594 | WP_003689161.1 | GTP cyclohydrolase II | - |
| HT081_RS02250 (TUM15753C_04200) | - | 454772..455446 (-) | 675 | WP_172760565.1 | hypothetical protein | - |
| HT081_RS02260 (TUM15753C_04210) | - | 455737..455931 (-) | 195 | WP_003689159.1 | AlpA family transcriptional regulator | - |
| HT081_RS11825 (TUM15753C_04220) | - | 455957..456169 (-) | 213 | WP_003698676.1 | hypothetical protein | - |
| HT081_RS11830 | - | 456141..456371 (-) | 231 | WP_003695893.1 | hypothetical protein | - |
| HT081_RS02270 (TUM15753C_04230) | - | 456368..457351 (-) | 984 | WP_050170976.1 | hypothetical protein | - |
| HT081_RS02275 (TUM15753C_04240) | - | 457462..457677 (-) | 216 | WP_003691538.1 | hypothetical protein | - |
| HT081_RS02280 (TUM15753C_04250) | - | 457729..458220 (-) | 492 | WP_004464807.1 | siphovirus Gp157 family protein | - |
| HT081_RS02285 (TUM15753C_04260) | - | 458217..458399 (-) | 183 | WP_003691535.1 | hypothetical protein | - |
| HT081_RS02290 (TUM15753C_04270) | - | 458539..459225 (-) | 687 | WP_012503754.1 | phage replication initiation protein, NGO0469 family | - |
| HT081_RS02295 (TUM15753C_04280) | - | 459294..459455 (-) | 162 | WP_003693867.1 | hypothetical protein | - |
| HT081_RS02300 (TUM15753C_04290) | - | 459452..459730 (-) | 279 | WP_003691529.1 | NGO1622 family putative holin | - |
| HT081_RS02305 (TUM15753C_04310) | - | 459883..460215 (-) | 333 | WP_003687946.1 | hypothetical protein | - |
| HT081_RS02310 (TUM15753C_04320) | - | 460356..460643 (-) | 288 | WP_050155496.1 | hypothetical protein | - |
| HT081_RS02315 (TUM15753C_04330) | - | 460640..461116 (-) | 477 | WP_012504141.1 | hypothetical protein | - |
| HT081_RS02320 (TUM15753C_04340) | - | 461149..461349 (-) | 201 | WP_003692842.1 | hypothetical protein | - |
| HT081_RS02325 (TUM15753C_04350) | - | 461547..461960 (-) | 414 | WP_003687963.1 | hypothetical protein | - |
| HT081_RS02330 (TUM15753C_04360) | - | 461957..462418 (-) | 462 | WP_003687965.1 | helix-turn-helix transcriptional regulator | - |
| HT081_RS02335 (TUM15753C_04370) | - | 462435..462872 (-) | 438 | WP_003687967.1 | hypothetical protein | - |
| HT081_RS02340 (TUM15753C_04380) | - | 462987..463703 (-) | 717 | WP_003687969.1 | LexA family transcriptional regulator | - |
| HT081_RS02345 (TUM15753C_04390) | - | 463772..464008 (+) | 237 | WP_003687971.1 | Cro/CI family transcriptional regulator | - |
| HT081_RS02350 (TUM15753C_04400) | - | 464088..464243 (+) | 156 | WP_003689578.1 | hypothetical protein | - |
| HT081_RS02355 (TUM15753C_04410) | - | 464220..464408 (-) | 189 | WP_003691445.1 | hypothetical protein | - |
| HT081_RS02360 (TUM15753C_04420) | - | 464581..464808 (+) | 228 | WP_003698261.1 | helix-turn-helix domain-containing protein | - |
| HT081_RS11835 (TUM15753C_04440) | - | 464926..465393 (+) | 468 | WP_229692802.1 | hypothetical protein | - |
| HT081_RS11840 (TUM15753C_04450) | - | 465488..465991 (+) | 504 | WP_010360005.1 | hypothetical protein | - |
| HT081_RS02370 (TUM15753C_04460) | - | 465988..467349 (+) | 1362 | WP_172760560.1 | DnaB-like helicase C-terminal domain-containing protein | - |
| HT081_RS02375 (TUM15753C_04470) | - | 467366..467617 (+) | 252 | WP_172761191.1 | hypothetical protein | - |
| HT081_RS02380 (TUM15753C_04480) | - | 467631..468125 (+) | 495 | WP_172760575.1 | DUF3310 domain-containing protein | - |
| HT081_RS02385 (TUM15753C_04490) | - | 468439..468588 (+) | 150 | WP_010360014.1 | hypothetical protein | - |
| HT081_RS11845 (TUM15753C_04500) | - | 468617..468898 (+) | 282 | WP_003689109.1 | hypothetical protein | - |
| HT081_RS02390 (TUM15753C_04510) | - | 468889..469326 (+) | 438 | WP_172760534.1 | RusA family crossover junction endodeoxyribonuclease | - |
| HT081_RS02395 (TUM15753C_04520) | - | 469319..469624 (+) | 306 | WP_003687981.1 | nuclease domain-containing protein | - |
| HT081_RS02400 (TUM15753C_04530) | - | 469621..470004 (+) | 384 | WP_003690918.1 | recombination protein NinB | - |
| HT081_RS02405 (TUM15753C_04540) | - | 469995..470513 (+) | 519 | WP_172760533.1 | HNH endonuclease signature motif containing protein | - |
| HT081_RS02410 (TUM15753C_04550) | - | 470578..471000 (+) | 423 | WP_003690919.1 | hypothetical protein | - |
| HT081_RS11850 (TUM15753C_04560) | - | 471000..471539 (+) | 540 | WP_003690920.1 | hypothetical protein | - |
| HT081_RS02425 (TUM15753C_04570) | - | 471520..472794 (+) | 1275 | WP_047919159.1 | PBSX family phage terminase large subunit | - |
| HT081_RS02430 (TUM15753C_04580) | - | 472779..475046 (+) | 2268 | WP_225577699.1 | hypothetical protein | - |
| HT081_RS02435 (TUM15753C_04590) | - | 475284..476480 (+) | 1197 | WP_003693452.1 | hypothetical protein | - |
| HT081_RS02440 (TUM15753C_04600) | - | 476477..483784 (+) | 7308 | WP_172762838.1 | PLxRFG domain-containing protein | - |
| HT081_RS02450 (TUM15753C_04620) | - | 484410..485705 (+) | 1296 | WP_003693441.1 | DUF4043 family protein | - |
| HT081_RS02455 (TUM15753C_04630) | - | 485764..486237 (+) | 474 | WP_113852114.1 | hypothetical protein | - |
| HT081_RS02460 (TUM15753C_04640) | - | 486243..486728 (+) | 486 | WP_003693438.1 | hypothetical protein | - |
| HT081_RS02465 (TUM15753C_04650) | - | 486725..487378 (+) | 654 | WP_227719074.1 | hypothetical protein | - |
| HT081_RS02470 (TUM15753C_04660) | - | 487401..487550 (+) | 150 | WP_017146863.1 | hypothetical protein | - |
| HT081_RS02475 (TUM15753C_04670) | - | 487587..488438 (-) | 852 | WP_003693432.1 | Bro-N domain-containing protein | - |
Sequence
Protein
Download Length: 149 a.a. Molecular weight: 16834.81 Da Isoelectric Point: 9.7951
>NTDB_id=81062 HT081_RS02155 WP_002214937.1 441420..441869(+) (comP) [Neisseria gonorrhoeae strain TUM15753]
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYVEKAKINAVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYVEKAKINAVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK
Nucleotide
Download Length: 450 bp
>NTDB_id=81062 HT081_RS02155 WP_002214937.1 441420..441869(+) (comP) [Neisseria gonorrhoeae strain TUM15753]
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATGTTGAGAAAGCAAAGATAAATGCAGTGCGGGCAGCCTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGATTTAAACAAACATCTACCAAATGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATCGCGCGCGGGGCTTTAGACAGTAAATTCATGTTGAAGGCGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAAAATCTAGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGTAGTGACG
GGCTGGATTATTTTAAAGGAAATGATAAGGACTGCAAGTTACTTAAGTAG
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATGTTGAGAAAGCAAAGATAAATGCAGTGCGGGCAGCCTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGATTTAAACAAACATCTACCAAATGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATCGCGCGCGGGGCTTTAGACAGTAAATTCATGTTGAAGGCGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAAAATCTAGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGTAGTGACG
GGCTGGATTATTTTAAAGGAAATGATAAGGACTGCAAGTTACTTAAGTAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comP | Neisseria gonorrhoeae MS11 |
100 |
100 |
1 |
| comP | Neisseria meningitidis 8013 |
99.329 |
100 |
0.993 |
| comP | Neisseria subflava NJ9703 |
49.66 |
98.658 |
0.49 |