Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   RMP65_RS02235 Genome accession   NZ_CP135089
Coordinates   429301..429942 (+) Length   213 a.a.
NCBI ID   WP_024413700.1    Uniprot ID   -
Organism   Streptococcus suis strain ID34567     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 424301..434942
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RMP65_RS02215 (RMP65_02215) - 424602..425339 (+) 738 WP_004194145.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  RMP65_RS02220 (RMP65_02220) pknB 425339..427003 (+) 1665 Protein_399 Stk1 family PASTA domain-containing Ser/Thr kinase -
  RMP65_RS10270 - 427118..427333 (+) 216 Protein_400 serine/threonine protein kinase -
  RMP65_RS02225 (RMP65_02225) liaF 427621..428316 (+) 696 WP_012774984.1 cell wall-active antibiotics response protein LiaF -
  RMP65_RS02230 (RMP65_02230) - 428313..429329 (+) 1017 WP_002937028.1 sensor histidine kinase -
  RMP65_RS02235 (RMP65_02235) vraR 429301..429942 (+) 642 WP_024413700.1 response regulator transcription factor Regulator
  RMP65_RS02240 (RMP65_02240) - 429992..431392 (+) 1401 WP_313680638.1 Cof-type HAD-IIB family hydrolase -
  RMP65_RS02245 (RMP65_02245) - 431394..431765 (+) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -
  RMP65_RS02250 (RMP65_02250) cysK 431791..432717 (-) 927 WP_002937015.1 cysteine synthase A -
  RMP65_RS02255 (RMP65_02255) - 432807..433439 (-) 633 WP_313680639.1 YigZ family protein -
  RMP65_RS02260 (RMP65_02260) comFA/cflA 433496..434788 (+) 1293 WP_313680640.1 DEAD/DEAH box helicase Machinery gene

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23818.41 Da        Isoelectric Point: 4.8970

>NTDB_id=808917 RMP65_RS02235 WP_024413700.1 429301..429942(+) (vraR) [Streptococcus suis strain ID34567]
MNTIRVMLVDDHEMVRLGLKSYLNLQPDVEVVAEASDGEEGLAKALEVKPDVVVMDLVMPKMTGVEATLALLKEWPQAQI
VILTSYLDNEKIYPVLEAGARGYMLKTSSADEILVAIRKVAIGEYAIETEVEKKVEHHKRHPDLHDDLTAREREILTLLA
KGYDNQRIADESFISLKTVKTHVSNILSKLAVSDRTQAVVYAFQHGLVAQEDQ

Nucleotide


Download         Length: 642 bp        

>NTDB_id=808917 RMP65_RS02235 WP_024413700.1 429301..429942(+) (vraR) [Streptococcus suis strain ID34567]
ATGAATACGATTCGAGTGATGCTGGTTGACGACCATGAGATGGTTCGTCTAGGATTGAAAAGTTACTTAAATTTACAGCC
AGATGTTGAAGTAGTTGCAGAAGCTAGTGATGGCGAGGAAGGTTTGGCTAAAGCATTAGAGGTTAAACCCGATGTTGTAG
TGATGGACTTGGTTATGCCCAAGATGACTGGCGTAGAAGCAACCTTGGCCTTGCTGAAGGAATGGCCGCAAGCGCAGATT
GTCATCCTGACCTCCTACCTAGATAATGAGAAAATCTATCCTGTGCTAGAAGCAGGAGCTCGTGGCTATATGTTGAAAAC
GTCAAGTGCTGACGAAATCTTAGTAGCCATCCGCAAGGTAGCTATTGGAGAATATGCTATTGAGACAGAAGTAGAGAAAA
AAGTAGAGCACCATAAACGCCACCCAGATTTACATGATGACTTGACAGCTCGTGAACGCGAAATCTTGACGCTGTTAGCC
AAGGGATATGATAATCAACGAATTGCAGATGAGTCCTTCATTTCCCTAAAAACTGTTAAGACCCATGTTTCCAATATCTT
ATCCAAACTAGCTGTTAGCGATCGTACTCAAGCAGTTGTTTATGCTTTCCAGCATGGTTTGGTGGCGCAAGAGGACCAAT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.589

97.183

0.531
  degU Bacillus subtilis subsp. subtilis str. 168

38.938

100

0.413