Detailed information NTG0080786

Bioinformatically predicted

Overview

• Name: comB4
• Type: Machinery gene
• Locus tag: HXS60_RS01405
• Genome accession: NZ_AP023042
• Coordinates: 269779..272214 (+)
• Length: 811 a.a.
• NCBI ID: WP_176486634.1
• Uniprot ID: -
• Organism: Helicobacter suis strain NHP19-4004
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 264779..277214

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HXS60_RS01375 (NHP194004_02820)	-	265912..267087 (+)	1176	WP_064430215.1	site-specific DNA-methyltransferase	-
HXS60_RS01380 (NHP194004_02830)	-	267074..267940 (+)	867	WP_006565094.1	CfrBI family restriction endonuclease	-
HXS60_RS01385 (NHP194004_02840)	-	268110..268880 (+)	771	WP_034375711.1	hypothetical protein	-
HXS60_RS01390 (NHP194004_02850)	comB2	268913..269152 (+)	240	WP_050780158.1	TrbC/VirB2 family protein	Machinery gene
HXS60_RS01395 (NHP194004_02860)	comB3	269163..269426 (+)	264	WP_034375715.1	hypothetical protein	Machinery gene
HXS60_RS01400 (NHP194004_02870)	-	269419..269766 (+)	348	WP_143440944.1	hypothetical protein	-
HXS60_RS01405 (NHP194004_02880)	comB4	269779..272214 (+)	2436	WP_176486634.1	VirB4 family type IV secretion/conjugal transfer ATPase	Machinery gene
HXS60_RS09665 (NHP194004_02890)	-	272219..272428 (+)	210	WP_141556969.1	hypothetical protein	-
HXS60_RS01415 (NHP194004_02900)	-	272438..273529 (+)	1092	WP_176486635.1	VirB8/TrbF family protein	-
HXS60_RS01420 (NHP194004_02910)	-	273526..275055 (+)	1530	WP_006564108.1	TrbG/VirB9 family P-type conjugative transfer protein	-
HXS60_RS01425 (NHP194004_02920)	comB10	275045..276304 (+)	1260	WP_034375723.1	DNA type IV secretion system protein ComB10	Machinery gene

Sequence

Protein

• Length: 811 a.a.
• Molecular weight: 93620.10 Da
• Isoelectric Point: 8.2519

>NTDB_id=80786 HXS60_RS01405 WP_176486634.1 269779..272214(+) (comB4) [Helicobacter suis strain NHP19-4004]
MLSDLFTFCKHKSIDYLAGLMPKTYSMVEENNILGIYDSQFLITKQENLVGLLELQGLSYLNLMQQDLEHYFNARQSALD
SIPLGVHLRIVAKRRKEQIKQNTQIDNPYARAIIAGFESKEIYDNRYYLVFESTTGTLKSFFEKKKLEMSTSIAESQDNQ
ERSKQKNITFINKHSMLKATMQRISHALKDFNPRELNSQEALRFYAEYINGFNIPLKPKMGILSDSYIASDVEFRKDYFL
INFKGKTTYQRFVGVKNYENQTITSVALSCLLHYACELDIIFSIEPLGIFESLHFLKVRKKFSFVNFVKEELDRYIDLVQ
ASRLSMQKIALNVLIRAESKESLDRHTEAVLNLLNNEGLVSKEETIGMIPSYFSFFPGRMDLNYRARYQTSSVMAALILF
EKNNRGFKANSWGDMPLSVFKNLDHSPYLFNFHNQEVQHKGVLAHNIARVNGHTMIIGATGAGKTTLMSYLMMSALKYPN
LDILALDRLNGLYSFTKYFGGVYNNDEEFYINPLTLEDSKENVEFLWSFYTYMLGIESTNKRDKELTEDQNAVRNAIGSM
YADHKKKSKQQEAYEPYTLEEFTNTFIKTQSEQINGTLEPYLQNPIFNAREDCLEFKSRITTINMDSVINNQKDAGLLAY
YIFYKLIHRALHTNRGFFCFINEFKSYAQNALMNDKINLIITQARKVNGVVALALQDIHQLDEVKNADSFIKNMGTLIFY
PQKNINTDKLKDQFGIKLSDLERHFLENTNVSSHQILIKNMNDSTSNVVDVSLAALGKYLPIFSSNASTMAHIKHLIKQY
PTSWREVFVHG

Nucleotide

• Length: 2436 bp

>NTDB_id=80786 HXS60_RS01405 WP_176486634.1 269779..272214(+) (comB4) [Helicobacter suis strain NHP19-4004]
ATGCTAAGTGATTTGTTTACATTTTGCAAACACAAGAGCATTGACTATCTAGCAGGCTTGATGCCTAAAACCTACTCTAT
GGTTGAGGAAAATAATATTCTAGGCATCTACGATTCCCAATTTTTAATCACCAAACAAGAGAATTTAGTAGGGTTGTTGG
AATTGCAGGGCTTGAGTTACTTGAATTTGATGCAACAGGATTTAGAACATTACTTTAATGCCCGCCAGAGTGCATTAGAT
AGTATCCCTCTAGGTGTGCATCTAAGAATTGTGGCTAAAAGAAGAAAAGAGCAAATCAAGCAGAATACACAGATAGATAA
TCCTTATGCTAGGGCTATCATTGCAGGATTTGAGAGCAAAGAGATTTATGATAACCGCTACTATCTTGTCTTTGAGAGCA
CAACAGGCACGCTTAAGAGCTTTTTTGAAAAGAAAAAGCTAGAGATGAGCACTTCTATAGCAGAGAGCCAAGATAATCAA
GAGCGCTCCAAGCAAAAAAACATCACCTTTATTAACAAGCACTCCATGCTCAAAGCAACCATGCAGAGAATAAGCCATGC
ACTCAAAGACTTCAACCCTAGAGAGCTTAACAGCCAAGAAGCCCTTAGATTTTATGCCGAATATATCAATGGCTTTAACA
TTCCTTTAAAACCTAAAATGGGCATTCTCAGCGATAGTTATATTGCTAGTGATGTAGAATTTAGAAAAGATTACTTCCTG
ATCAATTTTAAGGGCAAAACCACCTACCAACGCTTTGTAGGCGTGAAAAACTATGAAAACCAAACCATCACTTCTGTGGC
TCTCTCTTGCTTGTTACACTATGCATGTGAGCTAGACATTATCTTTTCTATAGAGCCTTTGGGCATTTTTGAGAGTTTGC
ATTTCTTAAAAGTACGCAAGAAATTTAGTTTTGTTAATTTTGTCAAAGAGGAGTTAGATAGATACATTGATCTGGTGCAA
GCTTCTAGACTCTCTATGCAAAAAATTGCCTTGAATGTGCTCATCAGAGCAGAAAGCAAAGAGAGTTTAGACAGACACAC
TGAGGCGGTTTTAAACTTGCTTAACAATGAAGGCTTGGTGAGCAAAGAGGAGACTATCGGGATGATACCCTCTTACTTTT
CTTTCTTTCCGGGTCGGATGGACTTAAACTATAGAGCTAGATACCAGACTTCTAGCGTGATGGCGGCCTTGATCTTGTTT
GAAAAGAATAACAGGGGCTTTAAAGCCAACTCTTGGGGGGATATGCCCTTGAGCGTGTTTAAAAACTTAGATCACTCCCC
TTATTTATTCAATTTCCACAACCAAGAAGTGCAACACAAGGGCGTGTTAGCCCACAATATTGCTAGAGTCAATGGACACA
CGATGATTATCGGAGCAACAGGAGCAGGCAAGACCACCTTGATGAGCTATTTGATGATGAGTGCTTTGAAATACCCAAAT
TTAGACATTTTAGCCCTAGATAGACTCAATGGCTTGTATTCCTTCACTAAATACTTTGGAGGGGTGTATAACAATGATGA
GGAGTTTTACATTAACCCTTTGACTTTAGAGGACTCTAAAGAAAATGTAGAGTTTTTGTGGAGCTTTTATACTTACATGC
TAGGCATTGAATCTACCAACAAAAGAGATAAAGAGCTCACAGAAGATCAAAATGCCGTGCGCAATGCTATTGGGAGTATG
TATGCAGACCACAAGAAAAAGAGCAAGCAGCAAGAAGCCTATGAGCCCTATACCTTAGAAGAGTTCACCAACACCTTTAT
TAAGACACAATCTGAACAAATCAATGGCACTTTAGAGCCTTATTTGCAAAACCCCATTTTCAATGCCAGAGAGGATTGCC
TAGAGTTTAAAAGCCGCATCACCACCATTAATATGGATTCTGTGATCAACAACCAAAAAGACGCAGGGCTACTTGCTTAT
TACATTTTCTATAAGCTCATCCATAGAGCCTTGCACACCAATCGGGGCTTTTTTTGCTTCATTAATGAGTTTAAATCCTA
TGCGCAAAATGCGCTGATGAATGACAAGATTAATCTCATCATCACCCAAGCGCGCAAGGTCAATGGGGTGGTTGCTTTGG
CTTTGCAAGACATCCACCAGTTAGATGAAGTGAAAAATGCCGACAGCTTTATTAAAAATATGGGCACACTGATCTTCTAT
CCCCAAAAGAACATCAATACAGACAAGCTCAAAGACCAGTTTGGCATCAAACTTAGCGATTTAGAACGCCATTTCCTAGA
AAACACCAATGTTTCTAGCCACCAGATTTTAATTAAAAATATGAATGATAGCACTTCTAATGTGGTGGATGTGAGTTTGG
CTGCTCTAGGTAAGTATTTGCCTATCTTTAGTTCTAATGCCAGCACTATGGCACATATCAAGCATTTAATCAAACAATAC
CCAACTAGCTGGAGAGAAGTGTTTGTGCATGGGTAA

Domains

Predicted by InterproScan.

• CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB) (187-385)

• Helicase HerA, central domain (DUF87) (450-633)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB4	Helicobacter pylori 26695	51.549	99.507	0.513