Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   RM376_RS16355 Genome accession   NZ_CP134717
Coordinates   3387416..3389437 (-) Length   673 a.a.
NCBI ID   WP_000042530.1    Uniprot ID   Q0TJR9
Organism   Escherichia coli strain RIVM_C036204     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 3382416..3394437
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RM376_RS16320 (RM376_16320) ybhL 3382529..3383233 (-) 705 WP_000373624.1 Bax inhibitor-1/YccA family protein -
  RM376_RS16325 (RM376_16325) moaE 3383370..3383822 (-) 453 WP_000852287.1 molybdopterin synthase catalytic subunit MoaE -
  RM376_RS16330 (RM376_16330) moaD 3383824..3384069 (-) 246 WP_000611261.1 molybdopterin synthase sulfur carrier subunit -
  RM376_RS16335 (RM376_16335) moaC 3384062..3384547 (-) 486 WP_000080885.1 cyclic pyranopterin monophosphate synthase MoaC -
  RM376_RS16340 (RM376_16340) moaB 3384550..3385062 (-) 513 WP_000084639.1 molybdenum cofactor biosynthesis protein B -
  RM376_RS16345 (RM376_16345) moaA 3385084..3386073 (-) 990 WP_001298683.1 GTP 3',8-cyclase MoaA -
  RM376_RS16350 (RM376_16350) yvcK 3386470..3387378 (+) 909 WP_001298685.1 uridine diphosphate-N-acetylglucosamine-binding protein YvcK -
  RM376_RS16355 (RM376_16355) uvrB 3387416..3389437 (-) 2022 WP_000042530.1 excinuclease ABC subunit UvrB Machinery gene
  RM376_RS16360 (RM376_16360) bioD 3390016..3390693 (-) 678 WP_000030930.1 dethiobiotin synthase -
  RM376_RS16365 (RM376_16365) bioC 3390686..3391441 (-) 756 WP_000246762.1 malonyl-ACP O-methyltransferase BioC -
  RM376_RS16370 (RM376_16370) bioF 3391428..3392582 (-) 1155 WP_000638125.1 8-amino-7-oxononanoate synthase -
  RM376_RS16375 (RM376_16375) bioB 3392579..3393619 (-) 1041 WP_000951223.1 biotin synthase BioB -

Sequence

Protein


Download         Length: 673 a.a.        Molecular weight: 76211.09 Da        Isoelectric Point: 4.8843

>NTDB_id=807724 RM376_RS16355 WP_000042530.1 3387416..3389437(-) (uvrB) [Escherichia coli strain RIVM_C036204]
MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEF
FPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLH
LTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFDEEVERLSLFDPLTGQIVSTIPR
FTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLENNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGE
PPPTLFDYLPADGLLVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYVSATPGNYE
LEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDI
DTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPS
MAKAIGETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVPMDMSPKALQQKIHELE
GLMMQHAQNLEFEEAAQIRDQLHLLRELFIAAS

Nucleotide


Download         Length: 2022 bp        

>NTDB_id=807724 RM376_RS16355 WP_000042530.1 3387416..3389437(-) (uvrB) [Escherichia coli strain RIVM_C036204]
ATGAGTAAACCGTTCAAACTGAATTCCGCTTTTAAACCTTCTGGCGATCAGCCGGAGGCGATTCGACGTCTCGAAGAGGG
GCTGGAAGATGGCCTGGCGCACCAGACGTTACTTGGCGTGACTGGCTCCGGGAAAACCTTCACCATTGCCAATGTCATTG
CTGACCTTCAGCGCCCAACCATGGTACTTGCGCCCAACAAAACGCTGGCGGCCCAGCTGTATGGCGAAATGAAAGAATTC
TTTCCGGAAAACGCGGTGGAATATTTCGTCTCCTACTACGACTACTATCAGCCGGAGGCCTATGTACCGAGTTCCGACAC
CTTCATTGAGAAAGATGCCTCGGTAAACGAACATATCGAACAGATGCGTTTGTCCGCCACCAAAGCGATGCTGGAGCGGC
GTGATGTGGTTGTGGTGGCGTCTGTTTCCGCGATTTATGGTCTGGGCGATCCTGATTTATATCTCAAGATGATGCTCCAT
CTCACGGTCGGTATGATTATCGATCAGCGCGCGATCCTGCGCCGACTGGCGGAGCTGCAATATGCTCGTAATGATCAAGC
ATTCCAGCGTGGTACTTTCCGTGTTCGTGGCGAGGTGATTGATATCTTCCCGGCAGAATCGGATGACATTGCACTTCGCG
TGGAGCTGTTTGACGAGGAGGTGGAACGATTGTCGTTATTTGACCCGCTGACCGGGCAGATTGTTTCCACTATTCCACGT
TTTACCATCTACCCGAAAACGCACTACGTCACGCCACGCGAGCGCATCGTCCAGGCGATGGAGGAGATCAAAGAAGAGCT
GGCCGCCAGACGTAAAGTGCTATTGGAAAACAACAAACTGCTGGAAGAGCAGCGGCTGACCCAGCGTACCCAGTTTGATC
TGGAGATGATGAACGAGCTAGGCTACTGTTCGGGGATTGAGAACTACTCGCGCTTCCTCTCCGGTCGTGGACCGGGTGAG
CCACCGCCGACGCTGTTTGATTACCTGCCTGCTGATGGGCTGCTGGTGGTCGATGAATCTCACGTCACCATTCCACAAAT
TGGCGGCATGTATCGCGGTGACCGGGCGCGTAAAGAGACACTGGTGGAGTACGGCTTCCGCCTGCCATCAGCGCTGGATA
ACCGTCCGCTGAAATTTGAAGAGTTCGAAGCATTAGCGCCGCAAACCATCTATGTTTCGGCGACGCCGGGTAATTACGAG
CTGGAAAAATCCGGTGGCGATGTGGTGGATCAGGTGGTGCGTCCAACAGGCTTACTCGACCCGATTATCGAAGTGCGGCC
AGTGGCAACACAGGTGGATGATCTTCTTTCGGAGATTCGTCAGCGAGCGGCAATTAACGAACGCGTACTGGTTACAACTC
TGACCAAGCGGATGGCGGAAGATCTTACTGAATATCTCGAAGAACACGGTGAGCGCGTGCGTTATCTTCACTCAGATATC
GACACCGTCGAACGTATGGAGATTATCCGCGACTTGCGTCTGGGTGAGTTCGACGTATTGGTAGGGATCAACTTACTGCG
CGAAGGTCTGGATATGCCGGAAGTTTCGCTGGTGGCGATCCTCGACGCTGACAAAGAAGGCTTCCTGCGTTCCGAACGTT
CGTTGATCCAGACCATTGGTCGTGCGGCACGTAACGTTAACGGTAAAGCGATTCTCTACGGCGATAAGATCACCCCATCA
ATGGCGAAAGCGATTGGCGAAACCGAACGTCGCCGCGAGAAACAGCAGAAGTACAACGAGGAACACGGCATTACGCCGCA
AGGCTTGAACAAGAAAGTGGTCGATATCCTGGCGCTGGGGCAGAACATTGCCAAAACCAAAGCGAAGGGCAGAGGAAAAT
CGCGCCCGATTGTTGAGCCGGATAATGTGCCGATGGATATGTCGCCTAAAGCGTTACAGCAGAAGATCCATGAACTGGAA
GGGTTGATGATGCAACACGCGCAGAATCTGGAGTTCGAAGAAGCGGCGCAAATTCGTGACCAGTTGCATCTGTTGCGTGA
GCTGTTTATTGCCGCGTCGTGA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(634-667)

UvrB interaction domain (UvrB_inter)

(159-249)

Ultra-violet resistance protein B (UvrB)

(552-593)

Helicase conserved C-terminal domain (Helicase_C)

(436-544)

Type III restriction enzyme, res subunit (ResIII)

(13-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q0TJR9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

56.732

98.217

0.557
  uvrB Streptococcus pneumoniae R6

56.581

98.217

0.556
  uvrB Streptococcus pneumoniae D39

56.581

98.217

0.556