Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB10   Type   Machinery gene
Locus tag   HXS57_RS02255 Genome accession   NZ_AP023039
Coordinates   442682..443884 (+) Length   400 a.a.
NCBI ID   WP_176485821.1    Uniprot ID   -
Organism   Helicobacter suis strain NHP19-4003     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 432233..473902 442682..443884 within 0


Gene organization within MGE regions


Location: 432233..473902
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HXS57_RS02195 (NHP194003_04450) - 432233..432712 (+) 480 WP_034375662.1 hypothetical protein -
  HXS57_RS02200 (NHP194003_04460) comB2 432709..432993 (+) 285 WP_006563999.1 TrbC/VirB2 family protein Machinery gene
  HXS57_RS02205 (NHP194003_04470) comB3 433004..433267 (+) 264 WP_006564000.1 hypothetical protein Machinery gene
  HXS57_RS02210 (NHP194003_04480) - 433278..433514 (+) 237 WP_034375660.1 hypothetical protein -
  HXS57_RS02215 (NHP194003_04490) - 433514..436087 (+) 2574 WP_176485818.1 VirB4 family type IV secretion/conjugal transfer ATPase -
  HXS57_RS02220 (NHP194003_04500) - 436199..437461 (-) 1263 WP_176485819.1 RNA-guided endonuclease InsQ/TnpB family protein -
  HXS57_RS02225 (NHP194003_04510) tnpA 437496..437912 (+) 417 WP_034376938.1 IS200/IS605 family transposase -
  HXS57_RS02230 (NHP194003_04520) - 438037..438561 (+) 525 Protein_456 hypothetical protein -
  HXS57_RS02235 (NHP194003_04530) tnpA 438614..439042 (-) 429 WP_034376438.1 IS200/IS605 family transposase -
  HXS57_RS02240 (NHP194003_04540) - 439107..440372 (+) 1266 WP_073117560.1 RNA-guided endonuclease InsQ/TnpB family protein -
  HXS57_RS02245 (NHP194003_04550) - 440377..441021 (+) 645 Protein_459 type IV secretion system protein -
  HXS57_RS02250 (NHP194003_04560) - 441018..442685 (+) 1668 WP_176485820.1 TrbG/VirB9 family P-type conjugative transfer protein -
  HXS57_RS02255 (NHP194003_04570) comB10 442682..443884 (+) 1203 WP_176485821.1 DNA type IV secretion system protein ComB10 Machinery gene
  HXS57_RS02260 (NHP194003_04580) - 443868..446117 (+) 2250 WP_176485822.1 collagen-like protein -
  HXS57_RS02265 (NHP194003_04590) - 446130..447107 (+) 978 WP_176485823.1 hypothetical protein -
  HXS57_RS02270 (NHP194003_04600) - 447125..447379 (+) 255 WP_176485824.1 hypothetical protein -
  HXS57_RS02275 (NHP194003_04610) - 447384..448328 (+) 945 WP_006564526.1 CpaF/VirB11 family protein -
  HXS57_RS02280 (NHP194003_04620) - 448325..448843 (+) 519 WP_033588775.1 hypothetical protein -
  HXS57_RS02285 (NHP194003_04630) - 448840..451104 (+) 2265 WP_034375654.1 type IV secretory system conjugative DNA transfer family protein -
  HXS57_RS02290 (NHP194003_04640) - 451124..451597 (+) 474 Protein_468 hypothetical protein -
  HXS57_RS08970 (NHP194003_04650) - 451761..452081 (+) 321 WP_006564537.1 hypothetical protein -
  HXS57_RS02300 (NHP194003_04660) - 452094..454154 (+) 2061 WP_034375651.1 type IA DNA topoisomerase -
  HXS57_RS02305 (NHP194003_04670) - 454209..454679 (+) 471 WP_000965788.1 hypothetical protein -
  HXS57_RS02310 (NHP194003_04680) - 454649..454804 (+) 156 WP_158650290.1 hypothetical protein -
  HXS57_RS02315 (NHP194003_04690) - 454786..455391 (-) 606 WP_104705861.1 hypothetical protein -
  HXS57_RS02320 (NHP194003_04700) - 455369..455737 (-) 369 WP_021305613.1 hypothetical protein -
  HXS57_RS08975 - 455784..456451 (-) 668 Protein_475 AAA family ATPase -
  HXS57_RS02335 (NHP194003_04730) - 457089..457253 (+) 165 WP_006564534.1 hypothetical protein -
  HXS57_RS02340 (NHP194003_04740) - 457254..458306 (+) 1053 WP_040499211.1 ArdC family protein -
  HXS57_RS02345 (NHP194003_04750) - 458306..460162 (+) 1857 WP_176485348.1 hypothetical protein -
  HXS57_RS02350 (NHP194003_04760) - 460172..461605 (+) 1434 WP_104707234.1 hypothetical protein -
  HXS57_RS02355 (NHP194003_04770) - 461602..462852 (+) 1251 WP_006564531.1 P-type conjugative transfer protein TrbL -
  HXS57_RS02360 (NHP194003_04780) - 462864..464105 (+) 1242 WP_176485825.1 hypothetical protein -
  HXS57_RS02365 (NHP194003_04790) - 464109..464756 (-) 648 WP_104707240.1 hypothetical protein -
  HXS57_RS02370 (NHP194003_04800) - 465006..465486 (+) 481 Protein_483 hypothetical protein -
  HXS57_RS02375 (NHP194003_04810) - 465618..465869 (+) 252 WP_000006537.1 hypothetical protein -
  HXS57_RS02380 (NHP194003_04820) - 465841..466644 (+) 804 WP_034375708.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
  HXS57_RS02385 (NHP194003_04830) - 466962..468029 (-) 1068 WP_176485826.1 tyrosine-type recombinase/integrase -
  HXS57_RS02390 (NHP194003_04840) - 469126..471111 (-) 1986 WP_176485362.1 relaxase/mobilization nuclease domain-containing protein -
  HXS57_RS02395 (NHP194003_04850) - 472264..472431 (+) 168 Protein_488 ATP phosphoribosyltransferase regulatory subunit -
  HXS57_RS02400 (NHP194003_04860) - 472396..472878 (-) 483 WP_309298907.1 nitrate- and nitrite sensing domain-containing protein -
  HXS57_RS02405 (NHP194003_04870) - 473198..473902 (+) 705 WP_176485827.1 site-specific integrase -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 44808.55 Da        Isoelectric Point: 9.9651

>NTDB_id=80772 HXS57_RS02255 WP_176485821.1 442682..443884(+) (comB10) [Helicobacter suis strain NHP19-4003]
MKQSLLKKIGLVIGGFGALMALGLLANKGSNNNNKEEIYSIEESKFPLSDYFFEEVKEEPKKEENPKTITTPQPTAPTTT
NVSTNPIITDYSHLNSNLNKQNDTITHLQQVLQSPPKMKPKLKHTKEQLEFLNTRLKPLEPTKPAIKPETEYGVDSFSNL
KYKDIGTNEHKLLRTITADRMIPAFLITPISSQIAGKVTVQVESDIFASMGRAVLIPKGSKVIGYYNNNNQIGQYRLNIA
WTRIITPQGINIMLTNARGADVKGYNGLVGKYISRNFQRYGIPLLTNTLSNGLLIGITSALANQQNRKGDGNPFFGDYLL
MQLTRNTGMGINQVINQMLRQYGAQNPIIIIREGSRVFITPNLDIFIPKPKDGEVLAEFFKEKKPLIKKSNEEVNNEEEI

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=80772 HXS57_RS02255 WP_176485821.1 442682..443884(+) (comB10) [Helicobacter suis strain NHP19-4003]
ATGAAACAATCCTTACTTAAAAAAATCGGCTTAGTTATAGGGGGCTTTGGTGCTTTAATGGCATTAGGATTGCTTGCTAA
TAAAGGTTCAAACAATAACAATAAAGAAGAAATTTACAGCATAGAAGAAAGTAAATTCCCCTTAAGCGATTATTTCTTTG
AAGAAGTCAAAGAAGAACCAAAAAAAGAAGAAAACCCCAAAACAATAACTACGCCACAACCTACAGCTCCAACTACTACC
AATGTTTCAACTAATCCTATCATTACAGATTATAGTCATCTTAACAGCAATCTCAACAAGCAAAATGACACCATCACGCA
TTTGCAACAAGTTTTACAAAGCCCCCCTAAAATGAAACCTAAATTAAAGCATACTAAAGAGCAATTAGAGTTTTTAAACA
CACGCCTTAAACCTTTAGAACCAACTAAACCAGCCATTAAGCCTGAGACGGAATATGGCGTGGATAGTTTTAGCAATTTA
AAATATAAAGACATCGGCACTAATGAGCATAAGCTCTTAAGAACTATAACCGCTGATAGAATGATACCAGCCTTTTTAAT
CACGCCTATTAGTTCTCAAATCGCTGGAAAAGTAACCGTTCAAGTAGAGAGTGATATTTTTGCTTCTATGGGTAGAGCGG
TGTTAATTCCTAAAGGCTCTAAGGTTATAGGCTATTACAATAACAATAATCAAATCGGGCAATACCGCTTAAACATTGCT
TGGACTAGAATTATCACCCCTCAAGGCATAAATATCATGCTCACTAATGCAAGGGGGGCTGATGTGAAAGGCTATAATGG
CTTAGTAGGCAAATATATTAGCCGAAATTTTCAACGCTATGGTATCCCCTTACTCACTAACACGCTTTCTAATGGGCTTT
TAATAGGAATTACTTCAGCCTTAGCTAATCAACAAAATAGAAAAGGTGATGGCAACCCTTTTTTTGGGGATTACTTGCTT
ATGCAACTCACTAGAAACACAGGCATGGGGATTAACCAAGTTATCAATCAAATGCTAAGACAATACGGAGCGCAAAACCC
CATTATCATCATTAGAGAGGGGAGCAGAGTGTTTATTACCCCTAATTTAGACATCTTTATCCCCAAACCAAAAGATGGGG
AGGTTCTAGCGGAGTTTTTTAAAGAGAAAAAACCACTAATCAAAAAATCAAACGAGGAAGTTAATAATGAAGAAGAAATC
TAA

Domains

Predicted by InterproScan.

Bacterial conjugation TrbI-like protein (TrbI)

(175-365)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB10 Helicobacter pylori P1

52.926

98.25

0.52

Multiple sequence alignment