Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   RM375_RS16380 Genome accession   NZ_CP134715
Coordinates   3390074..3392095 (-) Length   673 a.a.
NCBI ID   WP_000042530.1    Uniprot ID   Q0TJR9
Organism   Escherichia coli strain RIVM_C040753     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 3385074..3397095
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RM375_RS16345 (RM375_16345) ybhL 3385187..3385891 (-) 705 WP_000373624.1 Bax inhibitor-1/YccA family protein -
  RM375_RS16350 (RM375_16350) moaE 3386028..3386480 (-) 453 WP_000852287.1 molybdopterin synthase catalytic subunit MoaE -
  RM375_RS16355 (RM375_16355) moaD 3386482..3386727 (-) 246 WP_000611261.1 molybdopterin synthase sulfur carrier subunit -
  RM375_RS16360 (RM375_16360) moaC 3386720..3387205 (-) 486 WP_000080885.1 cyclic pyranopterin monophosphate synthase MoaC -
  RM375_RS16365 (RM375_16365) moaB 3387208..3387720 (-) 513 WP_000084639.1 molybdenum cofactor biosynthesis protein B -
  RM375_RS16370 (RM375_16370) moaA 3387742..3388731 (-) 990 WP_001298683.1 GTP 3',8-cyclase MoaA -
  RM375_RS16375 (RM375_16375) yvcK 3389128..3390036 (+) 909 WP_001298685.1 uridine diphosphate-N-acetylglucosamine-binding protein YvcK -
  RM375_RS16380 (RM375_16380) uvrB 3390074..3392095 (-) 2022 WP_000042530.1 excinuclease ABC subunit UvrB Machinery gene
  RM375_RS16385 (RM375_16385) bioD 3392674..3393351 (-) 678 WP_000030930.1 dethiobiotin synthase -
  RM375_RS16390 (RM375_16390) bioC 3393344..3394099 (-) 756 WP_000246762.1 malonyl-ACP O-methyltransferase BioC -
  RM375_RS16395 (RM375_16395) bioF 3394086..3395240 (-) 1155 WP_000638125.1 8-amino-7-oxononanoate synthase -
  RM375_RS16400 (RM375_16400) bioB 3395237..3396277 (-) 1041 WP_000951223.1 biotin synthase BioB -

Sequence

Protein


Download         Length: 673 a.a.        Molecular weight: 76211.09 Da        Isoelectric Point: 4.8843

>NTDB_id=807546 RM375_RS16380 WP_000042530.1 3390074..3392095(-) (uvrB) [Escherichia coli strain RIVM_C040753]
MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEF
FPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLH
LTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFDEEVERLSLFDPLTGQIVSTIPR
FTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLENNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGE
PPPTLFDYLPADGLLVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYVSATPGNYE
LEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDI
DTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPS
MAKAIGETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVPMDMSPKALQQKIHELE
GLMMQHAQNLEFEEAAQIRDQLHLLRELFIAAS

Nucleotide


Download         Length: 2022 bp        

>NTDB_id=807546 RM375_RS16380 WP_000042530.1 3390074..3392095(-) (uvrB) [Escherichia coli strain RIVM_C040753]
ATGAGTAAACCGTTCAAACTGAATTCCGCTTTTAAACCTTCTGGCGATCAGCCGGAGGCGATTCGACGTCTCGAAGAGGG
GCTGGAAGATGGCCTGGCGCACCAGACGTTACTTGGCGTGACTGGCTCCGGGAAAACCTTCACCATTGCCAATGTCATTG
CTGACCTTCAGCGCCCAACCATGGTACTTGCGCCCAACAAAACGCTGGCGGCCCAGCTGTATGGCGAAATGAAAGAATTC
TTTCCGGAAAACGCGGTGGAATATTTCGTCTCCTACTACGACTACTATCAGCCGGAGGCCTATGTACCGAGTTCCGACAC
CTTCATTGAGAAAGATGCCTCGGTAAACGAACATATCGAACAGATGCGTTTGTCCGCCACCAAAGCGATGCTGGAGCGGC
GTGATGTGGTTGTGGTGGCGTCTGTTTCCGCGATTTATGGTCTGGGCGATCCTGATTTATATCTCAAGATGATGCTCCAT
CTCACGGTCGGTATGATTATCGATCAGCGCGCGATCCTGCGCCGACTGGCGGAGCTGCAATATGCTCGTAATGATCAAGC
ATTCCAGCGTGGTACTTTCCGTGTTCGTGGCGAGGTGATTGATATCTTCCCGGCAGAATCGGATGACATTGCACTTCGCG
TGGAGCTGTTTGACGAGGAGGTGGAACGATTGTCGTTATTTGACCCGCTGACCGGGCAGATTGTTTCCACTATTCCACGT
TTTACCATCTACCCGAAAACGCACTACGTCACGCCACGCGAGCGCATCGTCCAGGCGATGGAGGAGATCAAAGAAGAGCT
GGCCGCCAGACGTAAAGTGCTATTGGAAAACAACAAACTGCTGGAAGAGCAGCGGCTGACCCAGCGTACCCAGTTTGATC
TGGAGATGATGAACGAGCTAGGCTACTGTTCGGGGATTGAGAACTACTCGCGCTTCCTCTCCGGTCGTGGACCGGGTGAG
CCACCGCCGACGCTGTTTGATTACCTGCCTGCTGATGGGCTGCTGGTGGTCGATGAATCTCACGTCACCATTCCACAAAT
TGGCGGCATGTATCGCGGTGACCGGGCGCGTAAAGAGACACTGGTGGAGTACGGCTTCCGCCTGCCATCAGCGCTGGATA
ACCGTCCGCTGAAATTTGAAGAGTTCGAAGCATTAGCGCCGCAAACCATCTATGTTTCGGCGACGCCGGGTAATTACGAG
CTGGAAAAATCCGGTGGCGATGTGGTGGATCAGGTGGTGCGTCCAACAGGCTTACTCGACCCGATTATCGAAGTGCGGCC
AGTGGCAACACAGGTGGATGATCTTCTTTCGGAGATTCGTCAGCGAGCGGCAATTAACGAACGCGTACTGGTTACAACTC
TGACCAAGCGGATGGCGGAAGATCTTACTGAATATCTCGAAGAACACGGTGAGCGCGTGCGTTATCTTCACTCAGATATC
GACACCGTCGAACGTATGGAGATTATCCGCGACTTGCGTCTGGGTGAGTTCGACGTATTGGTAGGGATCAACTTACTGCG
CGAAGGTCTGGATATGCCGGAAGTTTCGCTGGTGGCGATCCTCGACGCTGACAAAGAAGGCTTCCTGCGTTCCGAACGTT
CGTTGATCCAGACCATTGGTCGTGCGGCACGTAACGTTAACGGTAAAGCGATTCTCTACGGCGATAAGATCACCCCATCA
ATGGCGAAAGCGATTGGCGAAACCGAACGTCGCCGCGAGAAACAGCAGAAGTACAACGAGGAACACGGCATTACGCCGCA
AGGCTTGAACAAGAAAGTGGTCGATATCCTGGCGCTGGGGCAGAACATTGCCAAAACCAAAGCGAAGGGCAGAGGAAAAT
CGCGCCCGATTGTTGAGCCGGATAATGTGCCGATGGATATGTCGCCTAAAGCGTTACAGCAGAAGATCCATGAACTGGAA
GGGTTGATGATGCAACACGCGCAGAATCTGGAGTTCGAAGAAGCGGCGCAAATTCGTGACCAGTTGCATCTGTTGCGTGA
GCTGTTTATTGCCGCGTCGTGA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(634-667)

UvrB interaction domain (UvrB_inter)

(159-249)

Ultra-violet resistance protein B (UvrB)

(552-593)

Helicase conserved C-terminal domain (Helicase_C)

(436-544)

Type III restriction enzyme, res subunit (ResIII)

(13-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q0TJR9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

56.732

98.217

0.557
  uvrB Streptococcus pneumoniae R6

56.581

98.217

0.556
  uvrB Streptococcus pneumoniae D39

56.581

98.217

0.556