Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   P4B11_RS00470 Genome accession   NZ_CP120652
Coordinates   82679..83308 (+) Length   209 a.a.
NCBI ID   WP_404968744.1    Uniprot ID   -
Organism   Staphylococcus aureus strain 205M     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 77679..88308
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P4B11_RS00445 (P4B11_00440) - 78055..79041 (-) 987 WP_000999717.1 aromatic acid exporter family protein -
  P4B11_RS00450 (P4B11_00445) map 79572..80330 (+) 759 WP_000636142.1 type I methionyl aminopeptidase -
  P4B11_RS00455 (P4B11_00450) - 80547..80933 (+) 387 WP_001110179.1 hypothetical protein -
  P4B11_RS00460 (P4B11_00455) liaF 80948..81649 (+) 702 WP_000149064.1 cell wall-active antibiotics response protein LiaF -
  P4B11_RS00465 (P4B11_00460) vraS 81646..82689 (+) 1044 WP_001017131.1 sensor histidine kinase Regulator
  P4B11_RS00470 (P4B11_00465) vraR 82679..83308 (+) 630 WP_404968744.1 two-component system response regulator VraR Regulator
  P4B11_RS00475 (P4B11_00470) - 83421..84638 (-) 1218 WP_000037075.1 YihY/virulence factor BrkB family protein -
  P4B11_RS00480 (P4B11_00475) - 84916..85191 (-) 276 WP_000428172.1 YtxH domain-containing protein -
  P4B11_RS00485 (P4B11_00480) - 85198..85662 (-) 465 WP_000228666.1 low molecular weight protein-tyrosine-phosphatase -
  P4B11_RS00490 (P4B11_00485) - 85809..86009 (+) 201 WP_000180460.1 DUF1128 family protein -
  P4B11_RS00495 (P4B11_00490) - 86012..87268 (+) 1257 WP_001795108.1 aminopeptidase -
  P4B11_RS00500 (P4B11_00495) - 87358..87888 (+) 531 WP_000184383.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23589.41 Da        Isoelectric Point: 5.3935

>NTDB_id=807448 P4B11_RS00470 WP_404968744.1 82679..83308(+) (vraR) [Staphylococcus aureus strain 205M]
MMIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMEDMDGVEATTQIKKDLPQIKVL
MLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=807448 P4B11_RS00470 WP_404968744.1 82679..83308(+) (vraR) [Staphylococcus aureus strain 205M]
ATGATGATTAAAGTATTGTTTGTGGATGATCATGAAATGGTACGTATAGGAATTTCAAGTTATCTATCAACGCAAAGTGA
TATTGAAGTAGTTGGTGAAGGCGCTTCTGGTAAAGAAGCAATTGCCAAAGCCCATGAGTTGAAGCCAGATTTAATTTTAA
TGGATTTACTTATGGAAGACATGGATGGTGTAGAAGCGACGACTCAGATTAAAAAAGATTTACCGCAAATTAAAGTATTA
ATGTTAACTAGTTTTATTGAAGATAAAGAGGTATATCGTGCATTAGATGCAGGTGTCGATAGTTACATTTTAAAAACAAC
AAGTGCAAAAGATATCGCCGATGCAGTTCGTAAAACTTCTAGAGGAGAATCTGTTTTTGAACCGGAAGTTTTAGTGAAAA
TGCGTAACCGTATGAAAAAGCGCGCAGAGTTATATGAAATGCTTACAGAACGAGAAATGGAAATATTATTATTGATTGCG
AAAGGTTACTCAAATCAAGAAATTGCTAGTGCATCGCATATTACTATTAAAACGGTTAAGACACATGTGAGTAACATTTT
AAGTAAGTTAGAAGTGCAAGATAGAACACAAGCTGTCATCTATGCATTCCAACATAATTTAATTCAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

99.522

100

0.995
  degU Bacillus subtilis subsp. subtilis str. 168

34.821

100

0.373