Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   RLT59_RS08350 Genome accession   NZ_CP134612
Coordinates   1871444..1872121 (-) Length   225 a.a.
NCBI ID   WP_311302828.1    Uniprot ID   -
Organism   Streptomyces sp. ITFR-6     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1866444..1877121
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RLT59_RS08335 (RLT59_08335) - 1867642..1868661 (-) 1020 WP_311302826.1 LacI family DNA-binding transcriptional regulator -
  RLT59_RS08340 (RLT59_08340) - 1869280..1870872 (-) 1593 WP_311302827.1 cation acetate symporter -
  RLT59_RS08345 (RLT59_08345) - 1870869..1871312 (-) 444 WP_311307648.1 DUF485 domain-containing protein -
  RLT59_RS08350 (RLT59_08350) vraR 1871444..1872121 (-) 678 WP_311302828.1 response regulator transcription factor Regulator
  RLT59_RS08355 (RLT59_08355) - 1872118..1873281 (-) 1164 WP_311302829.1 histidine kinase -
  RLT59_RS08360 (RLT59_08360) - 1873278..1873787 (-) 510 WP_311302830.1 CcdC protein domain-containing protein -
  RLT59_RS08365 (RLT59_08365) - 1873963..1876083 (-) 2121 WP_311302831.1 DNA topoisomerase IV subunit B -
  RLT59_RS08370 (RLT59_08370) - 1876522..1876755 (+) 234 WP_024489001.1 hypothetical protein -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 23835.34 Da        Isoelectric Point: 4.9644

>NTDB_id=806856 RLT59_RS08350 WP_311302828.1 1871444..1872121(-) (vraR) [Streptomyces sp. ITFR-6]
MTARVVVADDQSVVREGIVMLLGLLPGIEVVGSAKDGEEAVALVAEHAPDVVLMDLRMPRCDGVEATRRIREDHPATQVV
VLTTFAEDDSLFPALRAGARGYLTKDAGGDEIVRAIKAVLSGEAGLSPAVQRRLLEQVTTGPLPLAAGTEPELPDGMTPR
EAEVLVLIAEGMSNAEIARSLHISQATVKSHINNLFAKAGLRDRAQAVRYAYVRGLAQPPGASFT

Nucleotide


Download         Length: 678 bp        

>NTDB_id=806856 RLT59_RS08350 WP_311302828.1 1871444..1872121(-) (vraR) [Streptomyces sp. ITFR-6]
GTGACCGCGCGGGTGGTGGTGGCGGACGACCAGTCGGTGGTGCGCGAGGGAATCGTCATGCTGCTGGGCCTGCTGCCCGG
GATCGAGGTGGTCGGATCGGCGAAGGACGGGGAGGAGGCCGTCGCCCTGGTGGCTGAGCATGCCCCGGACGTGGTCCTGA
TGGACCTGCGCATGCCCCGCTGCGACGGCGTGGAGGCGACGCGCCGGATCCGCGAGGACCATCCCGCCACCCAGGTCGTC
GTGCTCACGACCTTCGCCGAGGACGATTCGCTCTTCCCCGCACTCCGGGCGGGGGCCCGCGGCTATCTCACCAAGGACGC
GGGGGGAGACGAGATCGTGCGGGCCATCAAGGCGGTGCTCTCGGGCGAGGCCGGGCTCTCGCCCGCCGTGCAGCGCCGGC
TCCTGGAGCAGGTCACCACGGGGCCGTTGCCACTGGCCGCGGGCACTGAGCCGGAGCTGCCCGACGGGATGACCCCGCGC
GAGGCGGAGGTGCTCGTCCTGATCGCCGAGGGGATGTCCAACGCGGAGATCGCCCGCAGCCTGCACATCTCCCAGGCCAC
CGTGAAGAGTCACATCAACAACCTGTTCGCCAAGGCGGGGCTCCGTGACCGCGCCCAGGCGGTCCGCTATGCGTACGTTC
GAGGGCTCGCACAGCCGCCCGGCGCATCCTTCACCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(157-211)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.908

96.889

0.387
  degU Bacillus subtilis subsp. subtilis str. 168

37.168

100

0.373