Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   P5W78_RS12410 Genome accession   NZ_CP120426
Coordinates   2594777..2595493 (+) Length   238 a.a.
NCBI ID   WP_001829999.1    Uniprot ID   C0LF82
Organism   Staphylococcus epidermidis strain 25FSE01     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2589777..2600493
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P5W78_RS12385 - 2591175..2591960 (+) 786 WP_001830000.1 carbon-nitrogen family hydrolase -
  P5W78_RS12390 hld 2592341..2592418 (-) 78 WP_002494082.1 delta-hemolysin -
  P5W78_RS12395 - 2592736..2593320 (+) 585 WP_218085244.1 accessory gene regulator AgrB -
  P5W78_RS12400 - 2593304..2593444 (+) 141 WP_001830021.1 cyclic lactone autoinducer peptide -
  P5W78_RS12405 - 2593471..2594760 (+) 1290 WP_277379832.1 GHKL domain-containing protein -
  P5W78_RS12410 agrA 2594777..2595493 (+) 717 WP_001829999.1 LytTR family DNA-binding domain-containing protein Regulator
  P5W78_RS12415 - 2595561..2596520 (-) 960 WP_218085243.1 carbohydrate kinase -
  P5W78_RS12420 - 2596527..2597999 (-) 1473 WP_002469009.1 sucrose-6-phosphate hydrolase -
  P5W78_RS12425 - 2598259..2599212 (-) 954 WP_002468995.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27936.97 Da        Isoelectric Point: 5.6250

>NTDB_id=805727 P5W78_RS12410 WP_001829999.1 2594777..2595493(+) (agrA) [Staphylococcus epidermidis strain 25FSE01]
MKIFVCEDDQRQREHMVSIIKNYIMIEEKPMELALATNDPYEVLEQSKELNDIGCYFLDIQLEADMNGIKLASEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPSELKMRIIDCLETAHTRLKLLSKESNVDTIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELAQLDERFFRCHNSFVINRHNIESIDSKERIVYFKNGENCFASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=805727 P5W78_RS12410 WP_001829999.1 2594777..2595493(+) (agrA) [Staphylococcus epidermidis strain 25FSE01]
ATGAAAATTTTTGTTTGTGAAGATGACCAAAGACAAAGAGAACATATGGTATCAATCATTAAAAACTACATAATGATTGA
AGAAAAGCCAATGGAGTTAGCCTTAGCAACAAATGATCCTTATGAGGTCTTAGAGCAATCAAAAGAACTTAATGACATTG
GTTGTTACTTCCTTGATATTCAATTAGAAGCTGATATGAACGGTATTAAATTAGCCAGTGAAATTCGTAAACATGATCCT
GTTGGTAATATTATATTTGTAACCAGTCACAGTGAACTGACTTATTTGACGTTTGTTTATAAAGTGGCTGCTATGGATTT
TATTTTTAAGGATGATCCATCTGAATTAAAAATGAGAATCATAGATTGTCTTGAAACAGCACATACACGACTCAAATTAT
TATCAAAAGAAAGTAATGTAGATACGATTGAGTTAAAGCGGGGAAGTAATTCAGTATACGTTCAATATGATGACATTATG
TTTTTTGAATCATCTACGAAATCTCATAGACTCATCGCACATCTTGATAATCGACAAATTGAATTTTATGGAAATTTAAA
GGAATTAGCACAGCTTGATGAACGTTTCTTTAGATGTCATAACAGTTTTGTGATAAACAGGCATAATATTGAATCTATTG
ATTCAAAAGAACGTATTGTTTACTTTAAGAATGGCGAAAATTGTTTCGCTTCAGTACGTAATGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C0LF82

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

87.815

100

0.878
  comE/comE2 Streptococcus gordonii strain NCTC7865

35.178

100

0.374
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

35.178

100

0.374