Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   P3U53_RS04185 Genome accession   NZ_CP120189
Coordinates   929391..930020 (+) Length   209 a.a.
NCBI ID   WP_014613482.1    Uniprot ID   -
Organism   Staphylococcus pseudintermedius strain Dog012     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 924391..935020
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P3U53_RS04160 (P3U53_04160) - 925304..926302 (-) 999 WP_014613477.1 FUSC family protein -
  P3U53_RS04165 (P3U53_04165) map 926399..927160 (+) 762 WP_323693631.1 type I methionyl aminopeptidase -
  P3U53_RS04170 (P3U53_04170) - 927258..927647 (+) 390 WP_014613479.1 hypothetical protein -
  P3U53_RS04175 (P3U53_04175) liaF 927660..928361 (+) 702 WP_014613480.1 cell wall-active antibiotics response protein LiaF -
  P3U53_RS04180 (P3U53_04180) vraS 928358..929401 (+) 1044 WP_014613481.1 sensor histidine kinase Regulator
  P3U53_RS04185 (P3U53_04185) vraR 929391..930020 (+) 630 WP_014613482.1 response regulator transcription factor Regulator
  P3U53_RS04190 (P3U53_04190) - 930587..931168 (-) 582 WP_063278570.1 beta-class carbonic anhydrase -
  P3U53_RS04195 (P3U53_04195) - 931201..932538 (-) 1338 WP_015729387.1 YihY/virulence factor BrkB family protein -
  P3U53_RS04200 (P3U53_04200) - 932754..933041 (-) 288 WP_014613485.1 YtxH domain-containing protein -
  P3U53_RS04205 (P3U53_04205) - 933049..933507 (-) 459 WP_014613486.1 low molecular weight protein-tyrosine-phosphatase -
  P3U53_RS04210 (P3U53_04210) - 933641..933844 (+) 204 WP_014613487.1 DUF1128 family protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23484.17 Da        Isoelectric Point: 5.1671

>NTDB_id=804375 P3U53_RS04185 WP_014613482.1 929391..930020(+) (vraR) [Staphylococcus pseudintermedius strain Dog012]
MTIKVLFVDDHEMVRIGISSYLSTQPDIEVVGEGASGKEAIAKAHELKPDLILMDLVMTDMDGVEATMQIKKDLPHIKVV
MLTSYIEDKEVYRALDAGVDSYILKTTSANDIAEAVRKTSRGESVFEAEVLVKMRNRMKQRAELYELLTEREMEILLLIS
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHGLIE

Nucleotide


Download         Length: 630 bp        

>NTDB_id=804375 P3U53_RS04185 WP_014613482.1 929391..930020(+) (vraR) [Staphylococcus pseudintermedius strain Dog012]
ATGACAATTAAAGTATTATTTGTTGATGATCATGAAATGGTACGTATTGGGATTTCAAGTTATTTATCAACACAACCCGA
TATCGAAGTAGTGGGAGAAGGTGCCTCAGGTAAAGAAGCAATCGCAAAAGCCCACGAATTGAAACCAGATTTAATTTTAA
TGGATTTAGTGATGACGGATATGGACGGCGTTGAAGCGACAATGCAAATTAAGAAAGATTTGCCACATATTAAAGTCGTG
ATGCTGACGAGTTATATTGAAGATAAAGAAGTGTATCGAGCGTTAGATGCCGGTGTCGATAGTTACATTTTAAAAACGAC
GAGTGCGAATGATATTGCGGAAGCTGTACGTAAAACGAGTCGTGGTGAGTCTGTGTTTGAAGCGGAAGTATTAGTGAAAA
TGCGCAATCGAATGAAGCAGCGTGCGGAGTTATATGAATTGTTGACTGAGCGCGAGATGGAAATTTTGTTGTTGATTTCA
AAAGGCTATTCGAACCAAGAGATTGCGAGTGCATCACATATTACGATTAAGACAGTGAAGACGCATGTGAGTAATATTTT
AAGTAAGCTTGAGGTGCAGGATCGTACGCAAGCGGTTATTTATGCTTTCCAACACGGCTTGATTGAGTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

92.823

100

0.928
  degU Bacillus subtilis subsp. subtilis str. 168

35.714

100

0.383