Detailed information NTG0802931

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: P3T86_RS05050
• Genome accession: NZ_CP120099
• Coordinates: 1101692..1102735 (+)
• Length: 347 a.a.
• NCBI ID: WP_096808929.1
• Uniprot ID: A0A291JJJ1
• Organism: Staphylococcus nepalensis strain Dog109
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1096692..1107735

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P3T86_RS05025 (P3T86_05025)	-	1097744..1098469 (+)	726	WP_096808920.1	type 1 glutamine amidotransferase	-
P3T86_RS05030 (P3T86_05030)	-	1098570..1099556 (-)	987	WP_096808922.1	FUSC family protein	-
P3T86_RS05035 (P3T86_05035)	map	1099734..1100486 (+)	753	WP_103372572.1	type I methionyl aminopeptidase	-
P3T86_RS05040 (P3T86_05040)	-	1100591..1100977 (+)	387	WP_103372573.1	hypothetical protein	-
P3T86_RS05045 (P3T86_05045)	liaF	1100994..1101695 (+)	702	WP_096808927.1	cell wall-active antibiotics response protein LiaF	-
P3T86_RS05050 (P3T86_05050)	vraS	1101692..1102735 (+)	1044	WP_096808929.1	sensor histidine kinase	Regulator
P3T86_RS05055 (P3T86_05055)	vraR	1102725..1103354 (+)	630	WP_096808931.1	response regulator transcription factor	Regulator
P3T86_RS05060 (P3T86_05060)	-	1103427..1104518 (-)	1092	WP_103372574.1	YihY/virulence factor BrkB family protein	-
P3T86_RS05065 (P3T86_05065)	-	1104824..1105108 (-)	285	WP_096808936.1	YtxH domain-containing protein	-
P3T86_RS05070 (P3T86_05070)	-	1105115..1105579 (-)	465	WP_096808938.1	low molecular weight protein-tyrosine-phosphatase	-
P3T86_RS05075 (P3T86_05075)	-	1105712..1105915 (+)	204	WP_096808941.1	DUF1128 family protein	-
P3T86_RS05080 (P3T86_05080)	-	1105930..1107171 (+)	1242	WP_119488069.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39940.35 Da
• Isoelectric Point: 6.0563

>NTDB_id=802931 P3T86_RS05050 WP_096808929.1 1101692..1102735(+) (vraS) [Staphylococcus nepalensis strain Dog109]
MNHYIRAIGSMLILVYSTFFAMFFIDKVFVNIIYFQGMIYTQIFGIPVLLFINLLVILLCIIVGSVLAYKINQQNHWLQD
QIERSIEGQTVGINDQNIELYNETIELYQALVPLNQEVHKLRMKTQNLTNESYNMNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETELQAPLDQQIPVLEKMVQDSQLEMRALLLHLRPIGLKDKSLGQGIKDLVVDLQKKVPMKVVHDI
EDFKVPKGIEDHLFRITQEAISNTLRHSKGTKVTIELFNREEYLLLRIQDDGKGFNVDDKVEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSNAD

Nucleotide

• Length: 1044 bp

>NTDB_id=802931 P3T86_RS05050 WP_096808929.1 1101692..1102735(+) (vraS) [Staphylococcus nepalensis strain Dog109]
ATGAATCACTACATAAGAGCAATAGGGTCAATGTTGATATTAGTATATAGTACTTTTTTCGCCATGTTTTTTATAGACAA
AGTATTTGTTAATATCATATATTTCCAAGGCATGATTTACACACAAATATTTGGCATACCAGTTTTATTATTTATAAACT
TGTTAGTTATATTACTTTGTATCATCGTTGGATCTGTATTAGCATATAAAATTAATCAACAGAATCATTGGTTACAAGAT
CAAATTGAGCGCTCCATAGAAGGCCAAACAGTAGGTATCAATGACCAAAATATAGAGTTGTACAATGAAACCATTGAATT
ATATCAAGCACTGGTACCACTTAATCAAGAAGTTCACAAGTTGCGTATGAAAACGCAAAATTTAACAAACGAATCATATA
ATATGAATGACGTGAAAGTTAAAAAAATAATAGAAGACGAACGACAAAGGTTGGCTCGTGAACTACATGATTCTGTAAGC
CAACAATTATTTGCAGCAAGCATGATGCTTTCAGCAATTAAAGAAACTGAATTACAAGCGCCTTTAGATCAACAAATTCC
AGTACTCGAAAAAATGGTTCAAGATTCACAATTAGAAATGCGCGCATTACTATTACATTTAAGACCAATTGGTTTGAAGG
ATAAATCACTAGGCCAAGGTATCAAAGATTTAGTTGTTGACTTGCAGAAAAAAGTACCCATGAAAGTCGTACACGATATT
GAAGACTTCAAAGTACCCAAAGGTATTGAAGATCACTTATTTCGGATTACCCAAGAGGCAATTTCAAATACATTAAGACA
TTCGAAAGGTACTAAAGTTACAATTGAATTATTTAATAGAGAAGAATATTTATTATTACGTATACAAGATGACGGTAAAG
GCTTTAACGTAGATGATAAGGTAGAACAAAGTTATGGTTTGAAAAATATGCGAGAACGCGCCCTTGAAATTGGTGCAACT
TTCCATATCGTATCTCTGCCAGATTCAGGCACGCGAATTGAAGTCAAGGCCCCATTAAATAAGGAGGATTCAAATGCCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A291JJJ1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	86.744	100	0.867