Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   RJ646_RS03675 Genome accession   NZ_CP134358
Coordinates   754978..755637 (-) Length   219 a.a.
NCBI ID   WP_021568780.1    Uniprot ID   -
Organism   Escherichia coli strain TUM13936     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 749978..760637
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RJ646_RS03650 (RJ646_03650) - 750720..751667 (+) 948 WP_001305988.1 iron-siderophore ABC transporter substrate-binding protein -
  RJ646_RS03655 (RJ646_03655) - 751664..752551 (+) 888 WP_000614954.1 MurR/RpiR family transcriptional regulator -
  RJ646_RS03660 (RJ646_03660) ygiN 752596..752910 (-) 315 WP_000958598.1 putative quinol monooxygenase -
  RJ646_RS03665 (RJ646_03665) mdaB 752941..753522 (-) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  RJ646_RS03670 (RJ646_03670) qseC 753632..754981 (-) 1350 WP_000673348.1 quorum sensing histidine kinase QseC -
  RJ646_RS03675 (RJ646_03675) ciaR 754978..755637 (-) 660 WP_021568780.1 quorum sensing response regulator transcription factor QseB Regulator
  RJ646_RS03680 (RJ646_03680) ygiW 755789..756181 (+) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  RJ646_RS03685 (RJ646_03685) ygiV 756234..756716 (+) 483 WP_000183496.1 GyrI-like domain-containing protein -
  RJ646_RS03690 (RJ646_03690) ygiS 756825..758432 (+) 1608 WP_276270147.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24653.61 Da        Isoelectric Point: 6.9850

>NTDB_id=802822 RJ646_RS03675 WP_021568780.1 754978..755637(-) (ciaR) [Escherichia coli strain TUM13936]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKELALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=802822 RJ646_RS03675 WP_021568780.1 754978..755637(-) (ciaR) [Escherichia coli strain TUM13936]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTTTATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGCGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAACTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGTAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

37.885

100

0.393
  ciaR Streptococcus pneumoniae D39

37.885

100

0.393
  ciaR Streptococcus pneumoniae R6

37.885

100

0.393
  ciaR Streptococcus pneumoniae TIGR4

37.885

100

0.393
  ciaR Streptococcus mutans UA159

35.426

100

0.361