Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   P3U41_RS07915 Genome accession   NZ_CP120086
Coordinates   1512286..1513188 (+) Length   300 a.a.
NCBI ID   WP_096791887.1    Uniprot ID   -
Organism   Mammaliicoccus sciuri strain Dog116     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1507286..1518188
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P3U41_RS07875 (P3U41_07875) - 1507370..1507924 (+) 555 WP_096791884.1 5-formyltetrahydrofolate cyclo-ligase -
  P3U41_RS07880 (P3U41_07880) - 1507925..1509373 (+) 1449 WP_096791885.1 rhomboid family protein -
  P3U41_RS07885 (P3U41_07885) - 1509378..1509569 (+) 192 WP_078099923.1 YqgQ family protein -
  P3U41_RS07890 (P3U41_07890) - 1509566..1510537 (+) 972 WP_096791886.1 ROK family glucokinase -
  P3U41_RS07895 (P3U41_07895) - 1510537..1510851 (+) 315 WP_058611614.1 MTH1187 family thiamine-binding protein -
  P3U41_RS07900 (P3U41_07900) - 1510881..1511120 (-) 240 WP_016911885.1 DUF2759 domain-containing protein -
  P3U41_RS07905 (P3U41_07905) - 1511218..1511850 (+) 633 WP_058611613.1 MBL fold metallo-hydrolase -
  P3U41_RS07910 (P3U41_07910) - 1511884..1512132 (-) 249 WP_025904960.1 DUF2626 family protein -
  P3U41_RS07915 (P3U41_07915) comGA 1512286..1513188 (+) 903 WP_096791887.1 competence type IV pilus ATPase ComGA Machinery gene
  P3U41_RS07920 (P3U41_07920) comGB 1513178..1514218 (+) 1041 WP_196968298.1 competence type IV pilus assembly protein ComGB -
  P3U41_RS07925 (P3U41_07925) comGC 1514233..1514550 (+) 318 WP_058611611.1 competence type IV pilus major pilin ComGC Machinery gene
  P3U41_RS07930 (P3U41_07930) - 1514579..1514977 (+) 399 WP_049319406.1 hypothetical protein -
  P3U41_RS07935 (P3U41_07935) comGE 1514961..1515242 (+) 282 WP_196968297.1 competence type IV pilus minor pilin ComGE -
  P3U41_RS07940 (P3U41_07940) - 1515217..1515651 (+) 435 WP_323705719.1 competence type IV pilus minor pilin ComGF -
  P3U41_RS07945 (P3U41_07945) - 1515886..1516374 (+) 489 WP_323705720.1 shikimate kinase -
  P3U41_RS07950 (P3U41_07950) gcvT 1516567..1517655 (+) 1089 WP_196968294.1 glycine cleavage system aminomethyltransferase GcvT -

Sequence

Protein


Download         Length: 300 a.a.        Molecular weight: 34419.32 Da        Isoelectric Point: 6.1198

>NTDB_id=802748 P3U41_RS07915 WP_096791887.1 1512286..1513188(+) (comGA) [Mammaliicoccus sciuri strain Dog116]
MEKLFKSIINDAINSNASDIHFVPLNDDKVFVQMRINGDNIPYDLDLDFNLYSRLLIYMKFIAHLDVSERNKAQSGQYLF
EHDIHYYLRISTIPISLGIESSSIRITPQHFNHSQVKSEHQSYNVLQNRMYQSEGLFLFTGPTGSGKTTLMYELMYALKR
EKNKHIITIEDPVEQTLNGIVQVSVNEKANITYQQSFKAILRCDPDVIMIGEIRDDITAKQVIQASLSGHLVLSTMHASD
TIGAIHRLVELGVTVEQIKQGISCITNQRLVKKCDEARTLDMSYIFKDDIIKYMENDYET

Nucleotide


Download         Length: 903 bp        

>NTDB_id=802748 P3U41_RS07915 WP_096791887.1 1512286..1513188(+) (comGA) [Mammaliicoccus sciuri strain Dog116]
ATGGAGAAATTATTTAAGTCAATTATTAACGATGCTATCAATTCTAATGCGAGTGATATTCACTTTGTACCTTTAAACGA
TGATAAAGTCTTTGTCCAAATGAGGATAAATGGCGATAATATACCTTATGATTTAGATTTAGATTTTAATTTGTATAGTA
GGCTACTTATTTATATGAAATTTATCGCTCATCTAGATGTAAGTGAACGAAATAAAGCACAAAGTGGTCAATATTTATTT
GAACATGACATACATTACTATTTAAGAATTTCCACGATACCTATCAGTTTAGGGATAGAATCTAGTTCCATTAGAATAAC
CCCTCAACATTTTAATCATTCACAAGTGAAATCAGAGCATCAATCATATAACGTTCTACAAAACAGAATGTATCAATCAG
AAGGGCTATTTTTATTTACGGGTCCAACTGGATCAGGTAAGACTACATTAATGTATGAACTTATGTACGCATTAAAGAGA
GAGAAGAATAAACATATTATTACGATTGAAGACCCTGTAGAACAAACGTTAAATGGCATCGTTCAAGTTTCAGTCAATGA
AAAAGCTAACATAACTTATCAACAATCCTTTAAAGCCATTTTAAGATGTGATCCGGACGTTATTATGATTGGAGAGATAA
GAGATGATATTACTGCTAAGCAAGTTATTCAAGCTAGTTTAAGTGGTCATTTAGTACTTTCAACAATGCATGCGAGTGAT
ACAATCGGGGCAATCCACCGACTAGTTGAGCTAGGTGTAACAGTCGAACAAATTAAACAAGGTATTTCATGTATTACGAA
CCAACGTCTTGTGAAGAAATGTGATGAAGCAAGAACATTAGATATGTCCTATATTTTTAAAGATGACATTATTAAATATA
TGGAGAATGATTATGAAACGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(7-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Staphylococcus aureus MW2

52.5

93.333

0.49
  comGA Staphylococcus aureus N315

52.5

93.333

0.49
  comGA Bacillus subtilis subsp. subtilis str. 168

40.58

92

0.373
  pilB Haemophilus influenzae Rd KW20

35.032

100

0.367