Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   RI578_RS18855 Genome accession   NZ_CP134203
Coordinates   4120265..4120939 (-) Length   224 a.a.
NCBI ID   WP_310872160.1    Uniprot ID   A0ABP9TA50
Organism   Streptomyces sp. BB1-1-1     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4115265..4125939
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RI578_RS18830 (RI578_18830) - 4115385..4115900 (-) 516 WP_310872156.1 MarR family transcriptional regulator -
  RI578_RS18835 (RI578_18835) - 4115974..4116890 (+) 917 Protein_3734 ATP-binding cassette domain-containing protein -
  RI578_RS18840 (RI578_18840) - 4116887..4118503 (+) 1617 WP_310872157.1 ABC transporter permease -
  RI578_RS18845 (RI578_18845) - 4118823..4119005 (+) 183 WP_310872158.1 hypothetical protein -
  RI578_RS18850 (RI578_18850) - 4118988..4120211 (-) 1224 WP_310872159.1 cytochrome P450 -
  RI578_RS18855 (RI578_18855) vraR 4120265..4120939 (-) 675 WP_310872160.1 response regulator transcription factor Regulator
  RI578_RS18860 (RI578_18860) - 4120936..4122282 (-) 1347 WP_310872161.1 histidine kinase -
  RI578_RS18865 (RI578_18865) vraR 4122386..4123072 (-) 687 WP_210963164.1 response regulator transcription factor Regulator
  RI578_RS18870 (RI578_18870) - 4123127..4124494 (-) 1368 WP_310872162.1 sensor histidine kinase -
  RI578_RS18875 (RI578_18875) - 4124487..4125812 (-) 1326 WP_310872163.1 acyltransferase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 24184.88 Da        Isoelectric Point: 4.6621

>NTDB_id=802678 RI578_RS18855 WP_310872160.1 4120265..4120939(-) (vraR) [Streptomyces sp. BB1-1-1]
MSDRTIRVLIADDQMMVREGFSVLLNAMPDIEVAGEAVNGREAVAKVRELAPDVVLMDIRMPELNGIEATREIVAADGTS
KVLVLTTFDLDEYVYQALRAGASGFLLKDASARQLADGVRVVAAGEALLAPSITKRLITEFSKLSDAPRLMSSAQAAYGD
LTERETEVLVLIAQGLSNSEIAERLVVAESTIKTHVSRILVKLGLRDRTQAAVFAYEARLVTPG

Nucleotide


Download         Length: 675 bp        

>NTDB_id=802678 RI578_RS18855 WP_310872160.1 4120265..4120939(-) (vraR) [Streptomyces sp. BB1-1-1]
ATGAGCGACCGCACGATCCGGGTACTGATCGCGGACGACCAGATGATGGTGCGCGAGGGCTTCTCCGTCCTGCTGAACGC
GATGCCGGACATCGAGGTCGCCGGTGAGGCGGTCAACGGCCGGGAGGCCGTGGCGAAGGTCCGCGAGCTGGCTCCGGACG
TCGTCCTGATGGACATCCGCATGCCCGAGCTCAACGGCATCGAGGCGACGCGGGAGATCGTCGCGGCGGACGGCACGTCG
AAGGTGCTGGTCCTCACCACCTTCGACCTCGACGAGTACGTGTACCAGGCGCTGCGCGCGGGCGCCTCCGGCTTCCTCCT
CAAGGACGCCTCGGCCCGCCAGCTCGCCGACGGGGTCCGGGTGGTGGCCGCGGGCGAGGCCCTGCTCGCACCCTCCATCA
CCAAGCGTCTGATCACCGAGTTCTCCAAGCTGTCCGACGCCCCGCGCCTGATGTCCTCGGCCCAGGCGGCATACGGGGAC
CTGACCGAGCGGGAGACGGAGGTGCTGGTCCTGATCGCACAGGGCCTGTCCAATTCGGAGATCGCCGAGCGCCTGGTGGT
CGCCGAGTCGACGATCAAGACGCACGTCAGCCGCATCCTGGTGAAGCTGGGCCTCAGAGATCGCACCCAGGCGGCGGTCT
TCGCCTACGAGGCCCGCCTGGTGACGCCTGGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(8-117)

Bacterial regulatory proteins, luxR family (GerE)

(161-215)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

43.779

96.875

0.424
  degU Bacillus subtilis subsp. subtilis str. 168

41.475

96.875

0.402