Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   Q2K21_RS01170 Genome accession   NZ_CP134053
Coordinates   274841..275515 (+) Length   224 a.a.
NCBI ID   WP_310763172.1    Uniprot ID   A0ABV7SCZ7
Organism   Streptomyces sp. CGMCC 4.7035     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 269841..280515
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q2K21_RS01150 (Q2K21_01150) - 269867..271096 (+) 1230 WP_310763168.1 acyltransferase -
  Q2K21_RS01155 (Q2K21_01155) - 271107..272651 (+) 1545 WP_386275935.1 sensor histidine kinase -
  Q2K21_RS01160 (Q2K21_01160) vraR 272648..273322 (+) 675 WP_310763170.1 response regulator transcription factor Regulator
  Q2K21_RS01165 (Q2K21_01165) - 273498..274844 (+) 1347 WP_310763171.1 histidine kinase -
  Q2K21_RS01170 (Q2K21_01170) vraR 274841..275515 (+) 675 WP_310763172.1 response regulator transcription factor Regulator
  Q2K21_RS01175 (Q2K21_01175) - 275586..276806 (+) 1221 WP_310763173.1 cytochrome P450 -
  Q2K21_RS01180 (Q2K21_01180) - 277041..278651 (-) 1611 WP_310763174.1 ABC transporter permease -
  Q2K21_RS01185 (Q2K21_01185) - 278648..279562 (-) 915 WP_310763175.1 ABC transporter ATP-binding protein -
  Q2K21_RS01190 (Q2K21_01190) - 279666..280169 (+) 504 WP_310763176.1 MarR family transcriptional regulator -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 24116.84 Da        Isoelectric Point: 4.7568

>NTDB_id=801971 Q2K21_RS01170 WP_310763172.1 274841..275515(+) (vraR) [Streptomyces sp. CGMCC 4.7035]
MTGGTIRVLIADDQMMVREGFSVLLGAMPDIEVVGEAVNGREAVERVRELAPDVVLMDIRMPELNGIEATREIVAANGSA
KVLVLTTFDLDEYVYQALRAGASGFLLKDASARQLADGVRVVASGEALLAPSVTKRLISEFSKLSERPRLVPTAQGAYGD
LTERETEVLVLIAQGLSNAEIAERLVVAESTIKTHVSRILVKLGLRDRTQAAVFAYEARLVTPG

Nucleotide


Download         Length: 675 bp        

>NTDB_id=801971 Q2K21_RS01170 WP_310763172.1 274841..275515(+) (vraR) [Streptomyces sp. CGMCC 4.7035]
GTGACGGGGGGCACCATCCGCGTACTGATCGCCGACGACCAGATGATGGTCCGCGAGGGCTTCTCGGTGCTGCTCGGGGC
GATGCCGGACATCGAGGTCGTCGGGGAGGCGGTCAACGGGCGGGAGGCGGTCGAGCGGGTCCGTGAACTGGCCCCTGACG
TCGTGCTGATGGACATCCGCATGCCGGAGCTGAACGGCATCGAGGCGACCCGGGAGATCGTTGCCGCGAACGGGTCGGCG
AAGGTGCTGGTGCTGACCACGTTCGACCTCGACGAGTACGTCTACCAGGCACTGCGGGCGGGAGCCTCCGGTTTCCTCCT
CAAGGACGCGTCGGCGCGCCAGCTCGCCGACGGGGTGCGGGTGGTGGCGTCCGGCGAGGCCCTGCTGGCTCCCTCGGTGA
CCAAGCGGCTGATCTCGGAGTTCTCGAAGCTGTCCGAGCGACCGCGCCTCGTCCCCACCGCGCAGGGGGCGTACGGCGAT
CTGACCGAGCGGGAGACGGAGGTGCTGGTGCTCATCGCGCAGGGCCTGTCGAACGCGGAGATCGCCGAGCGGCTGGTGGT
CGCGGAGTCGACGATCAAGACCCATGTGAGCCGGATCCTGGTGAAGCTGGGCCTCAGGGACCGGACGCAGGCGGCGGTGT
TCGCGTACGAGGCGAGGCTGGTGACACCCGGCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(161-215)

Response regulator receiver domain (Response_reg)

(8-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.7

96.875

0.433
  degU Bacillus subtilis subsp. subtilis str. 168

42.857

96.875

0.415