Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   P3T93_RS00195 Genome accession   NZ_CP119997
Coordinates   45906..47255 (-) Length   449 a.a.
NCBI ID   WP_323701750.1    Uniprot ID   -
Organism   Staphylococcus cohnii strain Dog166     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 44426..61476 45906..47255 within 0


Gene organization within MGE regions


Location: 44426..61476
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P3T93_RS00195 (P3T93_00195) ccrA 45906..47255 (-) 1350 WP_323701750.1 cassette chromosome recombinase CcrA Machinery gene
  P3T93_RS00200 (P3T93_00200) - 47433..47690 (-) 258 WP_058332293.1 hypothetical protein -
  P3T93_RS00205 (P3T93_00205) cch1 47753..49543 (-) 1791 WP_270912362.1 cassette chromosome replicative helicase -
  P3T93_RS00210 (P3T93_00210) - 49543..49812 (-) 270 WP_031838353.1 hypothetical protein -
  P3T93_RS00215 (P3T93_00215) - 49967..51526 (-) 1560 WP_323701751.1 hypothetical protein -
  P3T93_RS00220 (P3T93_00220) - 51706..51996 (+) 291 Protein_41 FRG domain-containing protein -
  P3T93_RS00225 (P3T93_00225) - 52349..53320 (+) 972 WP_323701752.1 hypothetical protein -
  P3T93_RS00230 (P3T93_00230) - 53566..54000 (+) 435 WP_323701753.1 GNAT family N-acetyltransferase -
  P3T93_RS00235 (P3T93_00235) - 54248..54754 (+) 507 WP_019469178.1 hypothetical protein -
  P3T93_RS00240 (P3T93_00240) - 54772..56247 (+) 1476 WP_323701754.1 DUF6038 family protein -
  P3T93_RS00245 (P3T93_00245) - 56476..57576 (+) 1101 WP_071562281.1 DNA polymerase -
  P3T93_RS00250 (P3T93_00250) - 57569..57937 (+) 369 WP_041784734.1 hypothetical protein -
  P3T93_RS00255 (P3T93_00255) - 57937..59577 (+) 1641 WP_064264393.1 DUF5906 domain-containing protein -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 52027.81 Da        Isoelectric Point: 9.9932

>NTDB_id=801415 P3T93_RS00195 WP_323701750.1 45906..47255(-) (ccrA) [Staphylococcus cohnii strain Dog166]
MKQAIGYLRQSTTKQQSLAAQKQTIEALAKKHNIQYITFYSDKQSGRTDKRNGYQQITELIQQGQCDVLCCYRLNRLHRN
LKNALKLMKLCQKYHVHILSVHDGYFDMDKAFDRLKLNIFISLAELESDNIGEQVKNGIKEKAKQGKMITTHAPFGYQYH
NGTFTIDTVKASTIKAVFSYYLQGYGYKKIAQYLEADEKFINRKPYQVRNIIMNPNYCGRVINQYGQYDNMCPSIVSTSI
YEQAQAIRSQKQLKRTSSANQLKQKIKCPYCGSTLTNITIRKKHRTLRYYVCPQNMNASRFVCEFKGINAQSLEASVLAT
CQDFFQNQQLYSKINHTIQQRLKKQKDIEAKSTLTQEQLIEKLAQCKIDAETFREQTQSLCQQSKPISSIHTHQIRKALQ
NVIQQRFTLNMLYPYIDEIHITKSKTLTGIYFKNEPLNIVNQTAQSSIA

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=801415 P3T93_RS00195 WP_323701750.1 45906..47255(-) (ccrA) [Staphylococcus cohnii strain Dog166]
ATGAAACAAGCAATAGGTTACTTACGACAGAGCACTACAAAGCAACAATCCTTAGCAGCACAAAAACAAACCATCGAGGC
ATTAGCCAAAAAACATAATATTCAATACATTACCTTTTATAGCGATAAGCAATCAGGGCGCACTGATAAGCGGAACGGTT
ACCAACAAATTACTGAACTGATTCAACAAGGACAATGTGATGTATTATGTTGCTATCGTCTGAATCGACTTCATCGTAAT
CTAAAAAATGCATTAAAACTCATGAAATTATGTCAAAAATACCATGTTCATATCTTAAGCGTTCATGATGGCTATTTTGA
TATGGATAAAGCATTCGATCGGCTCAAACTCAATATTTTCATCAGCTTGGCCGAACTAGAATCCGATAATATAGGCGAAC
AAGTCAAAAATGGAATCAAAGAAAAAGCGAAACAAGGTAAAATGATTACAACACATGCACCCTTTGGGTATCAATATCAT
AATGGTACTTTCACGATAGACACAGTAAAAGCATCAACAATAAAAGCTGTATTCAGTTATTATCTTCAAGGCTATGGTTA
TAAAAAAATTGCACAGTACTTAGAAGCTGACGAGAAATTCATCAATCGTAAACCCTATCAAGTACGTAATATTATCATGA
ACCCCAATTATTGTGGTCGAGTCATTAATCAATACGGGCAATATGACAACATGTGTCCTTCTATTGTTTCGACAAGTATA
TATGAACAAGCTCAAGCGATACGATCACAAAAGCAACTCAAACGGACATCATCAGCTAATCAACTCAAACAAAAAATCAA
ATGTCCTTATTGTGGTTCAACGTTGACTAATATAACCATTAGAAAAAAGCACCGTACATTACGTTATTATGTCTGTCCAC
AAAATATGAATGCATCTCGTTTTGTCTGTGAATTCAAAGGAATCAACGCACAATCATTAGAAGCGAGTGTCTTAGCTACA
TGTCAAGACTTCTTTCAAAATCAACAGTTGTATTCAAAAATCAACCATACAATTCAACAACGACTCAAAAAACAAAAAGA
CATAGAAGCTAAAAGTACACTTACGCAAGAACAACTGATAGAAAAATTAGCCCAATGTAAAATTGATGCAGAAACATTCA
GAGAACAAACGCAATCATTATGTCAACAATCCAAACCTATATCATCAATCCATACGCATCAAATTCGAAAGGCTTTACAA
AATGTCATTCAACAACGTTTCACGTTAAACATGTTGTACCCTTACATCGATGAAATTCATATTACCAAAAGTAAAACGCT
TACAGGTATCTATTTCAAAAATGAGCCCTTAAACATCGTCAATCAAACAGCACAATCATCGATTGCTTAA

Domains

Predicted by InterproScan.

Resolvase, N terminal domain (Resolvase)

(4-147)

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-322)

Recombinase (Recombinase)

(170-250)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus COL

89.755

100

0.898
  ccrA Staphylococcus aureus N315

76.169

100

0.762