Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   Q3101_RS17820 Genome accession   NZ_CP133215
Coordinates   3875194..3875868 (+) Length   224 a.a.
NCBI ID   WP_064729004.1    Uniprot ID   A0A191V0W7
Organism   Streptomyces sp. VNUA74     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3870194..3880868
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q3101_RS17800 (Q3101_17800) - 3870465..3871688 (+) 1224 WP_226484241.1 acyltransferase -
  Q3101_RS17805 (Q3101_17805) - 3871681..3873057 (+) 1377 WP_256037009.1 sensor histidine kinase -
  Q3101_RS17810 (Q3101_17810) vraR 3873054..3873740 (+) 687 WP_064729002.1 response regulator transcription factor Regulator
  Q3101_RS17815 (Q3101_17815) - 3873854..3875197 (+) 1344 WP_308883778.1 histidine kinase -
  Q3101_RS17820 (Q3101_17820) vraR 3875194..3875868 (+) 675 WP_064729004.1 response regulator transcription factor Regulator
  Q3101_RS17825 (Q3101_17825) - 3875970..3877193 (+) 1224 WP_226484243.1 cytochrome P450 -
  Q3101_RS17830 (Q3101_17830) - 3877176..3877379 (-) 204 WP_308883779.1 hypothetical protein -
  Q3101_RS17835 (Q3101_17835) - 3877567..3879174 (-) 1608 WP_308883780.1 ABC transporter permease -
  Q3101_RS17840 (Q3101_17840) - 3879171..3880085 (-) 915 WP_308883782.1 ABC transporter ATP-binding protein -
  Q3101_RS17845 (Q3101_17845) - 3880159..3880665 (+) 507 WP_189397553.1 GbsR/MarR family transcriptional regulator -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 24086.92 Da        Isoelectric Point: 4.8446

>NTDB_id=798760 Q3101_RS17820 WP_064729004.1 3875194..3875868(+) (vraR) [Streptomyces sp. VNUA74]
MTGRTIRVLIADDQMMVREGFSVLLNAMPDIEVVGEAVNGREAVARVRELAPDVVLMDIRMPELNGIEATREIVAADGAA
KVLVLTTFDLDEYVYQALRAGASGFLLKDASARQLADGVRVVAAGEALLAPSITKRLITEFSKLSDAPRLMPSAQAAYGE
LTERETEVLVLIAQGLSNAEIAGRLVVAESTIKTHVSRILVKLGLRDRTQAAVFAYEARLVTPG

Nucleotide


Download         Length: 675 bp        

>NTDB_id=798760 Q3101_RS17820 WP_064729004.1 3875194..3875868(+) (vraR) [Streptomyces sp. VNUA74]
ATGACCGGCCGCACCATCCGGGTCCTGATCGCGGACGACCAGATGATGGTCCGCGAAGGTTTCTCGGTCCTGTTGAACGC
GATGCCGGACATCGAGGTCGTCGGCGAGGCGGTCAACGGCCGCGAGGCGGTCGCCCGCGTCCGCGAACTCGCCCCCGACG
TCGTCCTGATGGACATCCGCATGCCCGAGCTGAACGGCATCGAGGCGACCCGGGAGATCGTCGCCGCCGACGGCGCGGCG
AAGGTGCTGGTGCTGACCACCTTCGACCTCGACGAGTACGTGTACCAGGCGCTGCGCGCGGGCGCCTCCGGCTTCCTCCT
CAAGGACGCCTCGGCCCGTCAGCTGGCCGACGGGGTCCGGGTGGTCGCGGCCGGCGAGGCCCTGCTGGCGCCGTCGATCA
CCAAGCGCCTGATCACCGAGTTCTCCAAGCTCTCCGACGCCCCGCGCCTCATGCCGTCGGCGCAGGCGGCCTACGGGGAG
CTGACCGAGCGGGAGACCGAGGTCCTGGTGCTGATCGCGCAGGGCCTGTCGAACGCGGAGATCGCCGGGCGCCTGGTGGT
CGCCGAGTCGACGATCAAGACGCACGTCAGCCGCATCCTGGTGAAGCTGGGCCTCCGGGACCGCACCCAGGCCGCCGTGT
TCGCGTACGAGGCACGGCTGGTGACCCCGGGCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(161-215)

Response regulator receiver domain (Response_reg)

(8-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A191V0W7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

43.779

96.875

0.424
  degU Bacillus subtilis subsp. subtilis str. 168

41.475

96.875

0.402