Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   OO959_RS20925 Genome accession   NZ_AP026092
Coordinates   4145357..4145989 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 27_141091     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4140357..4150989
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OO959_RS20900 (CL8NIID27_40200) yheS 4140526..4142439 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  OO959_RS20905 (CL8NIID27_40210) yheT 4142439..4143461 (+) 1023 WP_000057377.1 hydrolase -
  OO959_RS20910 (CL8NIID27_40220) yheU 4143455..4143673 (+) 219 WP_000907085.1 YheU family protein -
  OO959_RS20915 (CL8NIID27_40230) prkB 4143727..4144596 (+) 870 WP_001274677.1 phosphoribulokinase -
  OO959_RS20920 (CL8NIID27_40240) yhfA 4144651..4145055 (-) 405 WP_001148908.1 OsmC family protein -
  OO959_RS20925 (CL8NIID27_40250) crp 4145357..4145989 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  OO959_RS20930 (CL8NIID27_40260) yhfK 4146040..4148130 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  OO959_RS20935 (CL8NIID27_40270) argD 4148197..4149417 (-) 1221 WP_000963819.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  OO959_RS20940 (CL8NIID27_40280) pabA 4149503..4150066 (-) 564 WP_000601867.1 aminodeoxychorismate synthase component 2 -
  OO959_RS20945 (CL8NIID27_40290) fic 4150098..4150700 (-) 603 WP_001280650.1 putative adenosine monophosphate-protein transferase Fic -
  OO959_RS20950 (CL8NIID27_40300) yhfG 4150690..4150857 (-) 168 WP_000736862.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=79803 OO959_RS20925 WP_000242755.1 4145357..4145989(+) (crp) [Escherichia coli strain 27_141091]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=79803 OO959_RS20925 WP_000242755.1 4145357..4145989(+) (crp) [Escherichia coli strain 27_141091]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCTGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTCAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment