Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   RA106_RS07020 Genome accession   NZ_CP132900
Coordinates   1359327..1361318 (-) Length   663 a.a.
NCBI ID   WP_014608579.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain CICC 20372     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1354327..1366318
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RA106_RS06995 (RA106_06990) - 1354667..1355461 (-) 795 WP_023909836.1 ABC transporter substrate-binding protein -
  RA106_RS07000 (RA106_06995) - 1355523..1356632 (-) 1110 WP_024703959.1 aminotransferase -
  RA106_RS07005 (RA106_07000) - 1356980..1357777 (-) 798 WP_014621828.1 transporter substrate-binding domain-containing protein -
  RA106_RS07010 (RA106_07005) - 1357774..1358604 (-) 831 WP_014621829.1 transporter substrate-binding domain-containing protein -
  RA106_RS07015 (RA106_07010) - 1358818..1359282 (-) 465 WP_011681454.1 8-oxo-dGTP diphosphatase -
  RA106_RS07020 (RA106_07015) uvrB 1359327..1361318 (-) 1992 WP_014608579.1 excinuclease ABC subunit UvrB Machinery gene
  RA106_RS07025 (RA106_07020) - 1361465..1361932 (-) 468 WP_014608580.1 hypothetical protein -
  RA106_RS07030 (RA106_07025) - 1362005..1362941 (-) 937 Protein_1345 CPBP family intramembrane glutamic endopeptidase -
  RA106_RS07035 (RA106_07030) - 1363140..1365349 (+) 2210 Protein_1346 ABC transporter substrate-binding protein/permease -
  RA106_RS07040 (RA106_07035) - 1365349..1366089 (+) 741 WP_024703961.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 663 a.a.        Molecular weight: 76115.22 Da        Isoelectric Point: 4.5966

>NTDB_id=797090 RA106_RS07020 WP_014608579.1 1359327..1361318(-) (uvrB) [Streptococcus thermophilus strain CICC 20372]
MIDRKEDNQFHLVSKYEPSGDQPQAIETLVDNIKGGEKAQILKGATGTGKTYTMSQVIQRVNKPTLVIAHNKTLAGQLYG
EFKEFFPDNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSINDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
DSAVSLRPGQEISRDKLLNDLVDIQFERNDIDFQRGKFRVRGDVVEIFPASRDENAFRVEFFGDEIDRICEIESLTGRNL
GEVEHLVLFPATHFMTNEEHMEEAIKNIMEEMEVQVNQFEAEGKLIEAQRIRQRTEYDVEMLREMGYTNGIENYSRHMDG
RKEGEPPFTLLDFFPEDFLIMIDESHMTMGQIKGMYNGDQARKKMLVDYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGDYEMEQTETVVEQIIRPTGLLDPEVEVRPTMGQMDDLLGEINARTEKGERVFVTTLTKKMAEDLTDYLKEMGVKVKYM
HSDIKTLERTEIIRDLRLGVFDVLIGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSDGHVIMYADK
ITESMQKAMDETARRREIQMAYNKEHGITPQTIKKEIRDLISITKTNEAEVAEDTVNYCAMNKKERQEAIKKLQKQMHEA
AELLDFELAAQIRDMVLELKSMD

Nucleotide


Download         Length: 1992 bp        

>NTDB_id=797090 RA106_RS07020 WP_014608579.1 1359327..1361318(-) (uvrB) [Streptococcus thermophilus strain CICC 20372]
ATGATAGATAGAAAAGAAGACAACCAATTTCATTTGGTTTCTAAATACGAACCCTCAGGAGATCAGCCCCAGGCTATCGA
AACCTTGGTTGATAATATCAAAGGTGGGGAGAAGGCTCAAATTTTAAAGGGTGCGACAGGGACAGGTAAGACCTATACCA
TGAGTCAAGTCATCCAACGTGTTAATAAGCCAACTCTGGTTATCGCCCACAATAAGACCTTGGCAGGCCAGCTCTATGGT
GAGTTCAAGGAGTTTTTCCCAGACAATGCTGTAGAGTATTTTGTTTCCTATTATGATTATTACCAGCCAGAGGCTTATGT
GCCTTCATCAGATACCTATATTGAAAAAGATAGCTCTATTAATGATGAAATTGATAAACTCCGTCACTCAGCGACATCAG
CCCTATTGGAACGCAATGATGTAATTGTTGTGGCTTCCGTGTCTTGTATTTACGGTTTGGGTTCGCCAAAAGAATATGCG
GATTCAGCTGTTAGCCTGCGTCCTGGTCAAGAAATTTCTCGGGACAAGTTGCTCAATGACTTGGTTGATATCCAGTTTGA
GCGTAACGATATTGATTTTCAACGCGGAAAATTCCGTGTACGTGGCGATGTGGTTGAAATTTTCCCTGCCAGCCGTGATG
AAAATGCTTTTCGAGTGGAATTTTTCGGTGATGAGATTGACCGTATCTGTGAAATTGAAAGTTTGACAGGACGTAATCTC
GGTGAAGTTGAGCACCTTGTTCTTTTTCCGGCTACTCACTTTATGACCAATGAAGAGCATATGGAAGAAGCTATCAAGAA
TATTATGGAAGAGATGGAGGTTCAGGTTAATCAATTTGAAGCCGAGGGTAAACTCATCGAGGCTCAACGTATTCGTCAAC
GGACAGAATACGATGTCGAAATGCTTCGTGAGATGGGTTACACCAATGGTATCGAAAACTACTCACGTCACATGGATGGT
CGTAAAGAAGGTGAGCCACCGTTTACTCTACTTGATTTCTTCCCAGAAGATTTCCTCATCATGATTGATGAAAGTCACAT
GACCATGGGACAGATTAAAGGAATGTATAACGGAGACCAAGCCCGTAAGAAGATGCTTGTCGATTACGGCTTCCGTTTAC
CATCGGCTCTTGATAACCGTCCCCTTCGTCGTGAAGAATTCGAAAGTCATGTGCATCAGATTGTCTATGTGTCAGCGACA
CCAGGTGACTATGAGATGGAGCAGACTGAGACTGTCGTTGAGCAAATCATCCGTCCGACAGGACTTCTTGATCCAGAAGT
CGAAGTTCGTCCAACTATGGGTCAAATGGATGACCTCCTTGGTGAAATCAATGCCCGTACTGAAAAAGGAGAGCGTGTCT
TTGTAACAACTTTGACTAAGAAGATGGCTGAGGACTTGACCGATTACCTCAAGGAAATGGGAGTCAAGGTCAAATACATG
CACTCTGATATTAAGACTTTGGAGCGTACTGAGATTATCCGTGACTTGCGTTTGGGTGTCTTTGATGTTCTTATTGGGAT
TAACCTTCTTCGTGAGGGTATTGACGTTCCTGAAGTTAGTCTGGTTGCTATTTTGGATGCTGATAAGGAAGGTTTCCTTC
GTAATGAACGTGGGCTTATCCAAACGATTGGACGTGCTGCCCGAAATAGTGATGGGCACGTTATCATGTATGCGGATAAG
ATTACGGAGTCTATGCAGAAAGCTATGGATGAAACTGCTCGTCGTCGTGAAATCCAAATGGCCTATAATAAGGAGCACGG
TATTACTCCGCAAACGATTAAGAAAGAAATTCGTGACCTTATTTCGATTACCAAGACCAATGAAGCAGAAGTGGCAGAGG
ATACTGTGAACTACTGTGCCATGAACAAGAAAGAACGCCAAGAAGCCATCAAGAAACTTCAAAAGCAAATGCACGAAGCG
GCAGAGCTGCTTGATTTTGAATTGGCAGCCCAAATTCGTGATATGGTTCTAGAGCTGAAGAGTATGGATTAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(628-660)

Ultra-violet resistance protein B (UvrB)

(556-598)

Helicase conserved C-terminal domain (Helicase_C)

(443-549)

Type III restriction enzyme, res subunit (ResIII)

(17-143)

UvrB interaction domain (UvrB_inter)

(164-254)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

85.219

100

0.852
  uvrB Streptococcus pneumoniae D39

85.219

100

0.852
  uvrB Streptococcus pneumoniae TIGR4

85.068

100

0.851