Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   PYW31_RS04540 Genome accession   NZ_CP118976
Coordinates   969713..970342 (+) Length   209 a.a.
NCBI ID   WP_046837881.1    Uniprot ID   A0A1S2MGW6
Organism   Staphylococcus succinus strain DSM 14617     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 964713..975342
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PYW31_RS04510 - 964748..965467 (+) 720 WP_046837887.1 type 1 glutamine amidotransferase -
  PYW31_RS04515 - 965561..966547 (-) 987 WP_046837886.1 FUSC family protein -
  PYW31_RS04520 map 966722..967474 (+) 753 WP_046837885.1 type I methionyl aminopeptidase -
  PYW31_RS04525 - 967579..967965 (+) 387 WP_046837884.1 hypothetical protein -
  PYW31_RS04530 liaF 967982..968683 (+) 702 WP_046837883.1 cell wall-active antibiotics response protein LiaF -
  PYW31_RS04535 vraS 968680..969723 (+) 1044 WP_046837882.1 sensor histidine kinase Regulator
  PYW31_RS04540 vraR 969713..970342 (+) 630 WP_046837881.1 response regulator transcription factor Regulator
  PYW31_RS04545 - 970538..971683 (-) 1146 WP_046837880.1 YihY/virulence factor BrkB family protein -
  PYW31_RS04550 - 971899..972183 (-) 285 WP_046837879.1 hypothetical protein -
  PYW31_RS04555 - 972183..972653 (-) 471 WP_046837878.1 low molecular weight protein-tyrosine-phosphatase -
  PYW31_RS04560 - 972787..972993 (+) 207 WP_082104728.1 DUF1128 family protein -
  PYW31_RS04565 - 973009..974250 (+) 1242 WP_046837877.1 aminopeptidase -
  PYW31_RS04570 - 974424..974945 (+) 522 WP_046837876.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23702.20 Da        Isoelectric Point: 4.6181

>NTDB_id=797071 PYW31_RS04540 WP_046837881.1 969713..970342(+) (vraR) [Staphylococcus succinus strain DSM 14617]
MPIKVLFVDDHEMVRIGISSYLSTQPDIDVVGEGKSGNEAIEKAHQLNPDLILMDLLMDDMDGVEATELIKKDLPHIKVV
MLTSYIEDNEVYRALDSGVDSYILKTTSASDIAEAIRKTYNDESVFEAEVLVKMRNRMKQRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=797071 PYW31_RS04540 WP_046837881.1 969713..970342(+) (vraR) [Staphylococcus succinus strain DSM 14617]
ATGCCGATTAAAGTTTTATTTGTTGATGATCATGAAATGGTACGAATAGGTATTTCTAGTTATTTATCAACACAACCAGA
TATTGATGTTGTAGGAGAAGGTAAGTCAGGGAATGAAGCGATAGAAAAAGCACATCAACTTAATCCAGATTTAATCCTCA
TGGACTTACTTATGGATGATATGGATGGTGTTGAAGCTACAGAACTTATTAAAAAAGATTTACCTCATATTAAAGTTGTC
ATGTTAACAAGTTACATTGAGGATAATGAAGTATACCGCGCCTTAGATTCAGGTGTGGACAGTTATATTTTAAAAACTAC
AAGTGCAAGTGATATTGCTGAAGCAATACGTAAGACATATAATGATGAGTCTGTATTTGAAGCAGAAGTATTAGTGAAAA
TGAGAAATAGAATGAAACAACGTGCCGAGTTATATGAAATGCTTACAGAACGTGAAATGGAAATTTTATTACTTATTGCT
AAAGGATACTCGAATCAAGAAATAGCTAGTGCTTCACATATTACAATCAAAACCGTTAAGACGCATGTAAGTAATATATT
AAGTAAATTGGAAGTACAAGATAGAACACAAGCAGTTATTTATGCGTTCCAACATAATTTAATACAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-117)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1S2MGW6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

88.517

100

0.885
  degU Bacillus subtilis subsp. subtilis str. 168

33.929

100

0.364