Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   PYH56_RS04340 Genome accession   NZ_CP118820
Coordinates   928501..929217 (-) Length   238 a.a.
NCBI ID   WP_196582891.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain 7057     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 923501..934217
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PYH56_RS04325 (PYH56_04325) - 924782..925735 (+) 954 WP_162154633.1 LacI family DNA-binding transcriptional regulator -
  PYH56_RS04330 (PYH56_04330) - 925995..927467 (+) 1473 WP_002457912.1 sucrose-6-phosphate hydrolase -
  PYH56_RS04335 (PYH56_04335) - 927474..928433 (+) 960 WP_002497210.1 carbohydrate kinase -
  PYH56_RS04340 (PYH56_04340) agrA 928501..929217 (-) 717 WP_196582891.1 LytTR family DNA-binding domain-containing protein Regulator
  PYH56_RS04345 (PYH56_04345) - 929234..930523 (-) 1290 WP_162154632.1 GHKL domain-containing protein -
  PYH56_RS04350 (PYH56_04350) - 930548..930688 (-) 141 WP_002487333.1 cyclic lactone autoinducer peptide -
  PYH56_RS04355 (PYH56_04355) - 930694..931257 (-) 564 WP_162154631.1 accessory gene regulator AgrB -
  PYH56_RS04360 (PYH56_04360) hld 931574..931651 (+) 78 WP_002494082.1 delta-hemolysin -
  PYH56_RS04365 (PYH56_04365) - 932032..932817 (-) 786 WP_162154630.1 carbon-nitrogen family hydrolase -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27954.94 Da        Isoelectric Point: 5.6250

>NTDB_id=795591 PYH56_RS04340 WP_196582891.1 928501..929217(-) (agrA) [Staphylococcus epidermidis strain 7057]
MKIFVCEDDQRQREHMVSIIKNYIMIEEKPMELTLATNDPYEVLEQSKELNDIGCYFLDIQLEADMNGIKLASEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPSELKMRITDCLETAHTRLKLLSKESNVDTIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELAQLDERFFRCHNSFVINRHNIESIDSKERIVYFKNGENCFASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=795591 PYH56_RS04340 WP_196582891.1 928501..929217(-) (agrA) [Staphylococcus epidermidis strain 7057]
ATGAAAATTTTTGTTTGTGAAGATGACCAAAGACAAAGAGAACATATGGTATCAATCATTAAAAACTACATAATGATTGA
AGAAAAGCCAATGGAGTTAACTTTAGCAACAAATGATCCTTATGAGGTTTTAGAGCAATCAAAAGAACTTAATGACATTG
GTTGTTACTTCCTTGATATTCAATTAGAAGCTGATATGAACGGTATTAAATTAGCCAGTGAAATTCGTAAACATGATCCT
GTTGGTAATATTATATTTGTAACCAGTCACAGTGAACTGACTTATTTGACATTTGTTTATAAAGTGGCTGCTATGGATTT
TATTTTTAAGGATGATCCATCTGAATTAAAAATGAGAATCACAGATTGTCTTGAAACAGCACATACACGACTCAAATTAT
TATCTAAAGAAAGTAATGTAGATACGATTGAGTTAAAACGTGGAAGTAATTCAGTATACGTTCAATATGATGATATTATG
TTTTTTGAATCATCTACGAAATCTCATAGACTCATCGCACATCTTGATAATCGACAAATTGAATTTTATGGAAATTTAAA
GGAATTAGCACAGCTTGATGAACGTTTCTTTAGATGTCATAACAGTTTTGTAATAAACAGACATAATATTGAATCTATTG
ATTCAAAAGAACGTATTGTTTACTTTAAGAATGGCGAAAATTGTTTCGCTTCAGTACGTAATGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

86.975

100

0.87
  comE/comE2 Streptococcus gordonii strain NCTC7865

35.178

100

0.374
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

35.178

100

0.374