Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   PYH57_RS08135 Genome accession   NZ_CP118810
Coordinates   1656692..1657666 (-) Length   324 a.a.
NCBI ID   WP_250426016.1    Uniprot ID   -
Organism   Staphylococcus aureus strain 7062     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1651692..1662666
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PYH57_RS08095 (PYH57_08085) gcvT 1652194..1653285 (-) 1092 WP_000093349.1 glycine cleavage system aminomethyltransferase GcvT -
  PYH57_RS08100 (PYH57_08090) - 1653444..1653968 (-) 525 WP_353458906.1 shikimate kinase -
  PYH57_RS08105 (PYH57_08095) - 1653958..1654104 (-) 147 WP_001789879.1 hypothetical protein -
  PYH57_RS08110 (PYH57_08100) comGF 1654201..1654698 (-) 498 WP_029656266.1 competence type IV pilus minor pilin ComGF Machinery gene
  PYH57_RS08115 (PYH57_08105) comGE 1654616..1654915 (-) 300 WP_000844413.1 hypothetical protein Machinery gene
  PYH57_RS08120 (PYH57_08110) comGD 1654902..1655347 (-) 446 Protein_1595 competence type IV pilus minor pilin ComGD -
  PYH57_RS08125 (PYH57_08115) comGC 1655325..1655636 (-) 312 WP_000472256.1 competence type IV pilus major pilin ComGC Machinery gene
  PYH57_RS08130 (PYH57_08120) comGB 1655650..1656720 (-) 1071 WP_000776417.1 competence type IV pilus assembly protein ComGB Machinery gene
  PYH57_RS08135 (PYH57_08125) comGA 1656692..1657666 (-) 975 WP_250426016.1 competence type IV pilus ATPase ComGA Machinery gene
  PYH57_RS08140 (PYH57_08130) - 1657718..1658341 (-) 624 WP_001223008.1 MBL fold metallo-hydrolase -
  PYH57_RS08145 (PYH57_08135) - 1658338..1658667 (-) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  PYH57_RS08150 (PYH57_08140) - 1658667..1659653 (-) 987 WP_000161315.1 ROK family glucokinase -
  PYH57_RS08155 (PYH57_08145) - 1659650..1659853 (-) 204 WP_000087561.1 YqgQ family protein -
  PYH57_RS08160 (PYH57_08150) - 1659834..1661297 (-) 1464 WP_001017867.1 rhomboid family intramembrane serine protease -
  PYH57_RS08165 (PYH57_08155) - 1661309..1661848 (-) 540 WP_000164552.1 5-formyltetrahydrofolate cyclo-ligase -
  PYH57_RS08170 (PYH57_08160) rpmG 1662057..1662206 (-) 150 WP_001265709.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 324 a.a.        Molecular weight: 36902.97 Da        Isoelectric Point: 8.8508

>NTDB_id=795464 PYH57_RS08135 WP_250426016.1 1656692..1657666(-) (comGA) [Staphylococcus aureus strain 7062]
MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNSIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYHF
NKIYFLRISTLPLSLGQESCVIRIVPQFFQQQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKVILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGISVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSNNHSLPSSFKNLEDKLDDMTKAGVICETTM
DKYI

Nucleotide


Download         Length: 975 bp        

>NTDB_id=795464 PYH57_RS08135 WP_250426016.1 1656692..1657666(-) (comGA) [Staphylococcus aureus strain 7062]
TTGAAGATTCTATTTCAAGAAATAATTAATAAAGCGATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA
TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTATGAACAAATTGGGAATAGCATTTATCAAAAGTTAT
TAGTTTATATGAAGTTTCAAGCTGGGCTTGATGTTTCTACACAGCAAGTCGCACAGAGCGGTCGATATAGTTACCATTTC
AATAAAATATATTTTTTGAGAATATCAACTTTACCATTGTCACTTGGCCAAGAAAGTTGTGTAATCAGAATTGTACCTCA
ATTTTTTCAACAACAGAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAATAAGAAACAAGGATTACTATTGT
TTAGTGGACCTACTGGTTCAGGAAAGAGTACATTAATGTATCAAATGGTCTCATACGCGAATAAAGCCTTGAATTTAAAT
GTAATTTCTATAGAAGATCCTGTAGAGATGCAAATTCCTGGTATTGTCCAAATTAATGTGAATGATAAAGCTGGCATTAA
CTATGTAAATTCGTTTAAAGTTATTTTAAGATGTGATCCTGATGTTATTTTAATAGGTGAAATCAGAGATAAAGATGTTG
CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTTGTTCTGACTACATTGCATGCAACTGATTGTAAAGGTGCTATT
TTAAGGCTATTAGAAATGGGCATTTCTGTACAAGAATTGATACAGGCAACTAACTTAATTATAAACCAACGACTTGTAAC
TACTATTAAGCAACAGCGACAATTAGTATGTGAAATTCTATCTCAGCAACAACTCCGATATTTCTTTTCCAATAATCATT
CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAACTACAATG
GATAAATACATTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(7-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Staphylococcus aureus MW2

99.383

100

0.994
  comGA Staphylococcus aureus N315

99.383

100

0.994