Detailed information NTG0795379

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: PYH68_RS04935
• Genome accession: NZ_CP118807
• Coordinates: 1072655..1073698 (+)
• Length: 347 a.a.
• NCBI ID: WP_042362410.1
• Uniprot ID: A0A5R9B245
• Organism: Staphylococcus xylosus strain 7064
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1067655..1078698

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PYH68_RS04910 (PYH68_04900)	-	1068609..1069331 (+)	723	WP_042362406.1	glutamine amidotransferase	-
PYH68_RS04915 (PYH68_04905)	-	1069534..1070520 (-)	987	WP_042362407.1	aromatic acid exporter family protein	-
PYH68_RS04920 (PYH68_04910)	map	1070697..1071449 (+)	753	WP_039069016.1	type I methionyl aminopeptidase	-
PYH68_RS04925 (PYH68_04915)	-	1071554..1071940 (+)	387	WP_042362408.1	hypothetical protein	-
PYH68_RS04930 (PYH68_04920)	liaF	1071957..1072658 (+)	702	WP_042362409.1	cell wall-active antibiotics response protein LiaF	-
PYH68_RS04935 (PYH68_04925)	vraS	1072655..1073698 (+)	1044	WP_042362410.1	sensor histidine kinase	Regulator
PYH68_RS04940 (PYH68_04930)	vraR	1073688..1074317 (+)	630	WP_017723494.1	response regulator transcription factor	Regulator
PYH68_RS04945 (PYH68_04935)	-	1074586..1075731 (-)	1146	WP_042362411.1	YihY/virulence factor BrkB family protein	-
PYH68_RS04950 (PYH68_04940)	-	1076087..1076371 (-)	285	WP_042362412.1	hypothetical protein	-
PYH68_RS04955 (PYH68_04945)	-	1076378..1076842 (-)	465	WP_042362413.1	low molecular weight protein-tyrosine-phosphatase	-
PYH68_RS04960 (PYH68_04950)	-	1076977..1077180 (+)	204	WP_017723498.1	DUF1128 family protein	-
PYH68_RS04965 (PYH68_04955)	-	1077198..1078436 (+)	1239	WP_042362414.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40037.55 Da
• Isoelectric Point: 6.4215

>NTDB_id=795379 PYH68_RS04935 WP_042362410.1 1072655..1073698(+) (vraS) [Staphylococcus xylosus strain 7064]
MNHYIRAIGSMLILVYSTFFAIFFIDKVFVNVMYFQGMFYTQIFGIPVLLFLNLMVILLCIIVGSVLAYKINQQNHWLKD
QIERSIEGQTVGINDQNIELYNETIELYQTLVPLNQEVHKLRMKTQNLTNESYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEAPLDQQIPVLEKMIQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVVDLQKKVPMKVIHDI
EEFKVPKGIEDHLFRITQEAISNTLRHSKGTKVTIELFNRDDYLLLRIQDNGKGFNVDDKVEQSYGLKNMRERALEIGAT
FHIVSLPDAGTRIEVKAPLNKEDSYAD

Nucleotide

• Length: 1044 bp

>NTDB_id=795379 PYH68_RS04935 WP_042362410.1 1072655..1073698(+) (vraS) [Staphylococcus xylosus strain 7064]
ATGAATCACTACATTAGAGCAATAGGTTCGATGTTGATATTAGTTTATAGTACATTTTTTGCTATATTTTTTATTGATAA
AGTATTTGTTAACGTAATGTACTTTCAAGGTATGTTTTATACCCAAATATTTGGTATACCCGTCTTATTATTTTTAAATT
TAATGGTTATTTTGCTCTGTATTATTGTTGGTTCTGTATTAGCTTATAAAATAAACCAACAAAATCATTGGTTAAAAGAC
CAAATAGAAAGATCAATAGAAGGGCAAACTGTAGGTATAAATGATCAAAATATAGAATTGTATAACGAAACCATTGAGTT
ATATCAAACGTTAGTCCCTTTAAATCAAGAAGTACATAAATTAAGGATGAAAACGCAAAATTTAACTAATGAATCATATA
ATATTAATGATGTAAAAGTGAAAAAAATTATTGAAGATGAACGACAAAGGCTAGCACGTGAATTACATGATTCAGTGAGT
CAGCAGTTGTTCGCAGCTAGCATGATGTTATCAGCAATAAAAGAAACAAAATTAGAGGCACCACTAGATCAGCAAATTCC
GGTACTAGAGAAAATGATTCAAGATTCTCAGCTAGAAATGAGAGCTTTATTACTACATTTAAGACCTATAGGCTTGAAAG
ATAAATCACTTGGTGAAGGTATTAAAGACTTAGTTGTAGATCTACAGAAAAAAGTACCGATGAAAGTTATACATGATATA
GAAGAATTTAAAGTACCTAAAGGTATTGAAGATCATTTATTTAGAATCACACAAGAAGCTATATCGAATACATTAAGGCA
TTCAAAAGGAACAAAAGTAACTATAGAGTTATTTAATAGAGATGATTATTTATTATTGAGAATACAAGATAATGGTAAAG
GCTTTAATGTTGATGATAAAGTAGAACAAAGTTATGGCTTAAAAAATATGCGTGAGCGTGCACTTGAGATTGGTGCAACG
TTTCATATTGTGTCACTACCTGATGCAGGTACCAGAATTGAAGTTAAAGCCCCATTAAATAAGGAGGATTCATATGCCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

3D structure

• AlphaFold DB: A0A5R9B245

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	88.473	100	0.885