Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccpA   Type   Regulator
Locus tag   PWK65_RS02240 Genome accession   NZ_CP118481
Coordinates   419545..420546 (+) Length   333 a.a.
NCBI ID   WP_002985680.1    Uniprot ID   A0A4U7H1B9
Organism   Streptococcus pyogenes strain 20185322     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 414545..425546
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PWK65_RS02215 (PWK65_02180) - 415219..415902 (-) 684 WP_002990714.1 DUF969 domain-containing protein -
  PWK65_RS02220 (PWK65_02185) - 416113..417039 (-) 927 WP_002990711.1 glycosyltransferase family 2 protein -
  PWK65_RS02225 (PWK65_02190) - 417184..417561 (-) 378 WP_002985686.1 VOC family protein -
  PWK65_RS02230 (PWK65_02195) - 417572..418237 (-) 666 WP_002985684.1 NAD(P)H-dependent oxidoreductase -
  PWK65_RS02235 (PWK65_02200) - 418286..419371 (-) 1086 WP_002990707.1 aminopeptidase P family protein -
  PWK65_RS02240 (PWK65_02205) ccpA 419545..420546 (+) 1002 WP_002985680.1 catabolite control protein A Regulator
  PWK65_RS02245 (PWK65_02210) - 420677..421675 (+) 999 WP_002990703.1 glycosyltransferase family 4 protein -
  PWK65_RS02250 (PWK65_02215) - 421677..423011 (+) 1335 WP_002990700.1 glycosyltransferase family 4 protein -
  PWK65_RS02255 (PWK65_02220) thrS 423433..425376 (+) 1944 WP_002985672.1 threonine--tRNA ligase -

Sequence

Protein


Download         Length: 333 a.a.        Molecular weight: 36713.83 Da        Isoelectric Point: 5.9985

>NTDB_id=792661 PWK65_RS02240 WP_002985680.1 419545..420546(+) (ccpA) [Streptococcus pyogenes strain 20185322]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide


Download         Length: 1002 bp        

>NTDB_id=792661 PWK65_RS02240 WP_002985680.1 419545..420546(+) (ccpA) [Streptococcus pyogenes strain 20185322]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

Periplasmic binding protein-like domain (Peripla_BP_3)

(177-332)

Bacterial regulatory proteins, lacI family (LacI)

(8-53)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4U7H1B9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccpA Streptococcus gordonii str. Challis substr. CH1

78.078

100

0.781
  ccpA Streptococcus pneumoniae D39

75.375

100

0.754
  ccpA Lactococcus lactis subsp. lactis strain DGCC12653

56.193

99.399

0.559